VEGFR-2-IN-77
VEGFR-2-IN-77 (Compound 10) is a VEGFR-2 inhibitor with an IC50 value of 139 nM. VEGFR-2-IN-77 inhibits the PI3K/AKT/mTOR pathway. VEGFR-2-IN-77 exhibits selective cytotoxicity, being particularly sensitive to leukemia and prostate cancer cells. VEGFR-2-IN-77 causes cell cycle arrest and apoptosis, inhibiting cell migration and invasion. VEGFR-2-IN-77 can be used for the study of leukemia and prostate cancer.
For research use only. We do not sell to patients.
- CAS No.: 169205-26-9
- Formula: C19H15N5O3
- Molecular Weight:361.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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VEGFR2 139 nM (IC50) |
Chemical Information
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CAS No. 169205-26-9
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Molecular Weight 361.35
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Formula C19H15N5O3
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SMILES
O=C1C(C)=NC2=CC=CC=C2N1CC(N/N=C3C(C=CC=C4)=C4NC/3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VEGFR-2-IN-77 Related Classifications
HY-179032 Related Classifications
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