20 Results for "

alkaline hydrolysis

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "alkaline hydrolysis" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P4846
CAS No.: 292171-04-1
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and acts as a CXCR2 agonist . Ac-Pro-Gly-Pro-OH exerts bactericidal activity by generating hydrogen peroxide, inhibits pulmonary inflammation, and reduces immune cell apoptosis (apoptosis). Ac-Pro-Gly-Pro-OH promotes the production of IFN-γ and inhibits the production of TNF-α and IL-6 in leukocytes. Ac-Pro-Gly-Pro-OH increases the survival rate of mice in sepsis models, enhances the bactericidal activity of neutrophils, acts as a neutrophil chemoattractant, induces neutrophil polarization, and regulates inflammatory and repair processes. Ac-Pro-Gly-Pro-OH induces chronic inflammation and tissue remodeling through sustained action. Ac-Pro-Gly-Pro-OH is released via alkaline hydrolysis of corneal proteins in alkali-injured eyes, thereby driving the early infiltration of neutrophils into the cornea. Ac-Pro-Gly-Pro-OH is applicable to research related to sepsis, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis obliterans syndrome, severe asthma, idiopathic pulmonary fibrosis, and corneal ulcer .
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1 Cited Publications
Cat. No.: HY-P2818
CAS No.: 9001-78-9
Synonyms: Apase
Alkaline phosphatase, Bovine intestine (Apase) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Bovine intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Bovine intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Bovine intestine improves TNBS-induced colon inflammation .
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1 Cited Publications
Cat. No.: HY-P2818E
CAS No.: 9001-78-9
Synonyms: Apase, Calf intestinal
Alkaline Phosphatase (Apase), Calf intestinal is an alkaline phosphatase from Calf intestinal, and is one of the most active alkaline phosphatases. Alkaline Phosphatase, Calf intestinal is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline Phosphatase, Calf intestinal reduces myeloperoxidase activity and bacterial translocation. Alkaline Phosphatase, Calf intestinal improves survival rate of mice infected with E. coli. Alkaline Phosphatase, Calf intestinal improves TNBS-induced colon inflammation .
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1 Cited Publications
Cat. No.: HY-P2818C
CAS No.: 9001-78-9
Synonyms: Apase, microorganism
Alkaline Phosphatase (Apase), microorganism is an alkaline phosphatase from microorganism, and is one of the most active alkaline phosphatases. Alkaline phosphatase, microorganism is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, microorganism reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, microorganism improves survival rate of mice infected with E. coli. Alkaline phosphatase, microorganism improves TNBS-induced colon inflammation .
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1 Cited Publications
Cat. No.: HY-P2818A
CAS No.: 9001-78-9
Synonyms: Apase, Escherichia coli
Alkaline Phosphatase (Apase), Escherichia coli is an alkaline phosphatase from Escherichia coli, and is one of the most active alkaline phosphatases. Alkaline phosphatase, Escherichia coli is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Escherichia coli reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Escherichia coli improves survival rate of mice infected with E. coli. Alkaline phosphatase, Escherichia coli improves TNBS-induced colon inflammation .
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1 Cited Publications
Cat. No.: HY-P2818B
CAS No.: 9001-78-9
Synonyms: Apase, Chicken Intestine
Alkaline Phosphatase (Apase), Chicken Intestine is an alkaline phosphatase from Chicken Intestine, and is one of the most active alkaline phosphatases. Alkaline phosphatase, Chicken Intestine is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Chicken Intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Chicken Intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Chicken Intestine improves TNBS-induced colon inflammation .
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Cat. No.: HY-W717548
CAS No.: 1160513-60-9
Target:  

Drug Metabolite

Research Areas:  

Others

Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples .
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Cat. No.: HY-156752
CAS No.: 452919-90-3
Purity:  99.68%
Target:  

Drug Metabolite

Research Areas:  

Others

Cyclosiversioside F 16,25-diacetate (Compound 6), a glycoside, is an alkaline hydrolysis product of Acetyl Derivative (Compound 2) .
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Cat. No.: HY-D1676
CAS No.: 123359-43-3
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .
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Cat. No.: HY-W923640
CAS No.: 487-59-2
Synonyms: N-Methyltryptophan
Target:  

Drug Derivative

Research Areas:  

Others

N-Methyl-DL-tryptophan (N-Methyltryptophan) is a DL-tryptophan (HY-W012480) derivative with activity to stabilize tryptophan against degradation during acid hydrolysis of protein fibres .
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Cat. No.: HY-136898
CAS No.: 86356-77-6
Target:  

Thrombin

Research Areas:  

Others

PS-915 dihydrochloride is a peptide substrate used in a colorimetric assay for plasma antithrombin III (ATIII). PS-915 dihydrochloride is highly specific for thrombin. By enzyme hydrolysis, PS-915 dihydrochloride liberates 3-carboxy-4-hydroxyaniline (CHA), which turns blue in color due to the complex formation with added alkaline-pentacyanoammine ferroate .
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Cat. No.: HY-138111
CAS No.: 129411-62-7
Synonyms: p-Nitopheyl β-D-cellotetaoside
4-Nitrophenyl β-D-cellotetraoside (p-Nitopheyl β-D-cellotetaoside) is a small molecule cellulose mimetic consisting of a tetramer of D-glucose units linked by β-1-4 glycosidic bonds. The fragmentation pattern of 4-Nitrophenyl β-D-cellotetraoside after enzymatic hydrolysis can be analyzed by TLC or by the release of 4-nitrophenol, which has a strong absorbance at 395 nm in alkaline solutions. 4-Nitrophenyl β-D-cellotetraoside can be used in cellulose degradation studies to determine the specificity of cellulases .
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Cat. No.: HY-N21528
CAS No.: 148031-70-3
Ilexosapogenin A is a triterpenoid natural product aglycone. Ilexosapogenin A can be obtained from crataeguside via enzymatic hydrolysis or alkaline hydrolysis. Ilexosapogenin A can be used in studies on triterpenoid natural products, structural identification of triterpenoid glycosides, and glycoside hydrolysis .
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Cat. No.: HY-W121884
CAS No.: 77182-37-7
Research Areas:  

Others

Fenclofenac glucuronide is the major urinary metabolite of Fenclofenac (HY-114806) in horses. Fenclofenac glucuronide undergoes intramolecular structural rearrangement to form a β-glucuronidase-resistant isomer, and releases Fenclofenac via complete alkaline hydrolysis .
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Cat. No.: HY-P2818F
CAS No.: 9001-78-9
Synonyms: Apase, Human (HEK293)
Alkaline phosphatase (Apase), Human (HEK293) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase improves survival rate of mice infected with E. coli. Alkaline phosphatase improves TNBS-induced colon inflammation .
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Cat. No.: HY-N13110
CAS No.: 1841090-13-8
23-Aldehyde-16-O-angeloybarringtogenol C (compound 7) is a tea seed saponin, an acid hydrolysis product obtained by oxidative alkaline degradation. Tea seed saponins have potential quinine oxidoreductase inducing activity .
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Cat. No.: HY-P11734
CAS No.: 72682-75-8
Target:  

Ser/Thr Protease

Research Areas:  

Others

Suc-AAPY-pNA is an oligptide compound and protease substrate. Suc-AAPY-pNA undergoes hydrolysis by proteases at the peptide bond between tyrosine and p-nitroaniline, releasing p-nitroaniline with an absorption peak at OD410. Suc-AAPY-pNA functions as a substrate in preclinical assays for measuring activity of acidic, neutral, and alkaline proteases .
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Cat. No.: HY-W019938
CAS No.: 7785-84-4
Synonyms: Trisodium cyclo-triphosphate
Target:  

Others

Research Areas:  

Others

Sodium trimetaphosphate (Trisodium cyclo-triphosphate) is an orally active, multifunctional compound. Sodium trimetaphosphate serves as a buffer and chelating agent in cosmetics, a starch modifier in food, and can also act as a bone imaging agent. Sodium trimetaphosphate undergoes alkaline hydrolysis, with the rate-limiting first step producing sodium tripolyphosphate; the conversion rate is low when sodium carbonate or silicate is used. Sodium trimetaphosphate can be used in caries-related research .
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Cat. No.: HY-N18361
CAS No.: 162341-29-9
Synonyms: Wujiapioside B
Oplopanaxoside C (Wujiapioside B) is a lupane-triterpene glycoside found in the leaves of Acanthopanax gracilistylus .
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Cat. No.: HY-180169
CAS No.: 3106369-28-9
Research Areas:  

Cancer

Photosensitizer-8 (Compound 4), 2-anthrol derivative, is an alkaline phosphatase (ALP)-activatable photosensitizer. Photosensitizer-8 undergoes a phosphate ester hydrolysis reaction in the presence of ALP, rapidly converting into the active photosensitizer 2-anthrol. Photosensitizer-8 exhibits cytotoxicity against ALP-overexpressing cancer cells (HeLa, A549, HCT116) after light exposure, with IC50 values of 14.3 μM, 21.6 μM and 17.5 μM, respectively, while showing no significant cytotoxicity against normal lung fibroblasts (WI-38) (IC50 ≥ 30 μM). Photosensitizer-8 can be used in photodynamic therapy research for ALP-overexpression-related cancers .
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