2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. Suc-AAPY-pNA

Suc-AAPY-pNA is an oligptide compound and protease substrate. Suc-AAPY-pNA undergoes hydrolysis by proteases at the peptide bond between tyrosine and p-nitroaniline, releasing p-nitroaniline with an absorption peak at OD410. Suc-AAPY-pNA functions as a substrate in preclinical assays for measuring activity of acidic, neutral, and alkaline proteases.

For research use only. We do not sell to patients.

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Suc-AAPY-pNA

Suc-AAPY-pNA Chemical Structure

CAS No. : 72682-75-8

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Suc-AAPY-pNA Related Antibodies

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Description

Suc-AAPY-pNA is an oligptide compound and protease substrate. Suc-AAPY-pNA undergoes hydrolysis by proteases at the peptide bond between tyrosine and p-nitroaniline, releasing p-nitroaniline with an absorption peak at OD410. Suc-AAPY-pNA functions as a substrate in preclinical assays for measuring activity of acidic, neutral, and alkaline proteases[1].

In Vitro

Suc-AAPY-pNA (4 mM stock solution; 10 min at 40 °C) functions as a valid substrate for measuring the activity of multiple protease types and variants, producing measurable OD410 absorbance signals that correlate with protease activity, with standard curve R2=0.9909, and yielding quantified activities ranging from 0.2 U/mL to 97.5 U/mL across tested proteases[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Suc-AAPY-pNA Related Antibodies
Molecular Weight

640.64

Formula

C30H36N6O10
CAS No.
Sequence

Suc-Ala-Ala-Pro-Tyr-pNA
Sequence Shortening

Suc-AAPY-pNA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Suc-AAPY-pNA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Suc-AAPY-pNA72682-75-8Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesprotease substratep-nitroanilinepeptide bondneutral proteasestyrosinealkaline proteasesacidic proteasesproteasesInhibitorinhibitorinhibit

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