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Results for "

biosynthetic intermediate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Intermediate (16) Acetolactate Synthase (ALS) (1) Antibiotic (1) Biochemical Assay Reagents (2) Cytochrome P450 (2) Drug Derivative (1) Drug Isomer (1) Endogenous Metabolite (6) Fungal (2) Isotope-Labeled Compounds (1) Parasite (1) Reference Standards (3) TRP Channel (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (8) Inflammation/Immunology (1) Metabolic Disease (4)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Drug Intermediate

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1247

Protoporphyrin IX 20+ Cited Publications PPIX	Endogenous Metabolite	Others
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-116956

D-Erythrose (50% in water)	Biochemical Assay Reagents	Others
D-Erythrose is a four-carbon sugar classified as an aldose. D-Erythrose has unique chemical properties that make it an important intermediate in various metabolic pathways, especially in the biosynthesis of amino acids and nucleotides. It also plays a role in the pentose phosphate pathway, which generates reducing equivalents for biosynthetic reactions and cellular defense against oxidative damage.

HY-N3926

Garbanzol	Drug Intermediate	Others
Garbanzol is an orally active natural flavonoid compound. Garbanzol is one of the key intermediates in the flavonoid biosynthetic pathway. Garbanzol exhibits anti-mutagenic activity .

HY-137261

UDP-β-D-glucose disodium	Endogenous Metabolite	Metabolic Disease
UDP-β-D-glucose disodium acts as a glycosyl donor and biosynthetic intermediate, and is also a stereoisomer of UDP-α-D-glucose .

HY-B1247R

Protoporphyrin IX (Standard) PPIX (Standard)	Reference Standards Endogenous Metabolite	Others
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-W077634

3-Amino-5-hydroxybenzoic acid AHBA	Drug Intermediate	Infection
3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose .

HY-P3519

ACV Tripeptide	Drug Intermediate	Infection
ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics .

HY-N1356A

(R)-Reticuline	Cytochrome P450	Inflammation/Immunology
(R)-Reticuline is a key intermediate and precursor in the biosynthetic pathway of morphinan alkaloids. (R)-Reticuline plays a central role in the metabolism of opium poppy (Papaver somniferum). (R)-Reticuline can either undergo O-methylation catalyzed by PSOMT1, or be converted to (+)-Salutaridine via regioselective and stereoselective oxidative coupling under the action of salutaridine synthase (CYP719B1). (R)-Reticuline serves as a direct precursor for the synthesis of important alkaloids such as morphine, codeine and thebaine .

HY-128425A

N-Carbamoyl-L-aspartic acid 1 Publications Verification L-Ureidosuccinic acid	Fungal	Infection
N-Carbamoyl-L-aspartic acid (L-Ureidosuccinic acid) is an important pyrimidine metabolic precursor and intermediate metabolite. N-Carbamoyl-L-aspartic acid reverses the growth inhibition of Ura ⁺ strains induced by 2-thiouracil (with growth rate increasing linearly with its concentration), but fails to support the growth of uracil-requiring Ura ^- strains. N-Carbamoyl-L-aspartic acid inhibits the cell growth of Saccharomyces cerevisiae by suppressing the purine biosynthetic pathway at a pre-step of 5-aminoimidazole nucleotide synthesis. The growth inhibitory effect of N-Carbamoyl-L-aspartic acid on yeast can be alleviated by purines, and the sensitivity of strains is closely related to the activity level of dihydroorotase .

HY-B1247A

Protoporphyrin IX disodium Maximum Cited Publications 22 Publications Verification PPIX disodium	Endogenous Metabolite	Cancer
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-W579377

Pantoic acid sodium	Drug Intermediate	Others
Sodium pantoate is a biosynthetic intermediate. Sodium pantoate is generated via hydroxymethylation of α-ketoisovalerate followed by reduction. Sodium pantoate combines with β-alanine via an amide bond to form pantothenic acid. Pantothenic acid has important biological significance .

HY-164170

Photocaged DAP pm-DAP	Drug Intermediate	Others
Photocaged DAP (pm-DAP) is a protected version of 2,3-Diaminopropionic acid (DAP) (HY-W013673). Photocaged DAP can produce 2,3-Diaminopropionic acid after photodeprotection. Photocaged DAP can be used as an intermediate to capture biosynthetic acylase .

HY-W715783

Divarinic acid Divaric acid; Divarinolic acid; Varinolic acid	Biochemical Assay Reagents	Others
Divarinic acid (also known as Divaric acid, Divarinolic acid, or Varinolic acid) serves as an intermediate in the biosynthetic pathway of phytocannabinoids, and can be used to synthesize the cannabinoid precursor CBGVA .

HY-136476G

Pt(II) protoporphyrin IX	Drug Intermediate	Others
Pt(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .

HY-W740803

15-cis-Phytofluene (15Z)-Phytofluene	Drug Intermediate Drug Isomer	Others
15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis .

HY-N12196

Terretonin	Cytochrome P450	Infection
Terretonin is a fungal terpenoid isolated from Aspergillus terreus. The complete biosynthetic pathway of terretonin includes: cytochrome P450 Trt6 catalyzes the oxidation of terrenoid to obtain an unstable intermediate; then it is catalyzed by isomerase Trt14 and processed by non-heme iron-dependent dioxygenase Trt7 to complete the biosynthesis of terretonin .

HY-110271

N-Acetylpuromycin	Antibiotic	Others
N-Acetylpuromycin is a inactive form of the antibiotic puromycin. N-Acetylpuromycin is the last intermediate of the puromycin antibiotic biosynthetic pathway in Streptomyces alboniger .

HY-136476F

Cd(II) protoporphyrin IX	Drug Intermediate	Others
Cd(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .

HY-136476E

Cr(III) protoporphyrin IX	Drug Intermediate	Others
Cr(III) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .

HY-N14823

Demethylmacrocin	Drug Intermediate	Others
Demethylmacrocin is a key intermediate in the biosynthetic pathway of Tylosin (HY-B0519A). Demethylmacrocin can be efficiently converted into tylosin through specific sequential oxidation and methylation reactions .

HY-145800

Photocaged DAP TFA pm-DAP TFA	Drug Intermediate	Others
Photocaged DAP (pm-DAP) TFA is a protected version of 2,3-Diaminopropionic acid (DAP) (HY-W013673). Photocaged DAP TFA can produce 2,3-Diaminopropionic acid after photodeprotection. Photocaged DAP TFA can be used as an intermediate to capture biosynthetic acylase .

HY-P3519A

ACV Tripeptide TFA	Drug Intermediate	Infection
ACV Tripeptide TFA, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide TFA is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide TFA can be used for the biosynthesis of β-lactam antibiotics .

HY-W016628R

L-Gulono-1,4-lactone (Standard) L-Gulonolactone (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
L-Gulono-1,4-lactone (L-Gulonolactone) (Standard) is the analytical standard of L-Gulono-1,4-lactone. This product is intended for research and analytical applications. L-Gulono-1,4-lactone is a biosynthetic precursor of L-Ascorbic acid (Vitamin C) (HY-B0166). L-Gulono-1,4-lactone can be enzymatically converted to L-Ascorbic acid via the animal uronic acid pathway, while species such as humans lack the key oxidase that catalyzes this step, resulting in the disruption of this pathway and the necessity to obtain Vitamin C from diet. L-Gulono-1,4-lactone is a putative intermediate in an alternative biosynthetic pathway of L-Ascorbic acid in Arabidopsis thaliana.

HY-178299S

3-Amino-5-hydroxybenzoic acid-13C	Isotope-Labeled Compounds Drug Intermediate	Infection
3-Amino-5-hydroxybenzoic acid- ¹³C is the ¹³C-labeled 3-Amino-5-hydroxybenzoic acid (HY-W077634). 3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose .

HY-N16458

FI-3	Drug Intermediate	Infection
FI-3 is a polycyclic tetramate macrolactam biosynthetic intermediate found in Streptomyces sp. SPB78. FI-3 is promising for research of antibiotics .

HY-W014394R

Vanillyl butyl ether (Standard)	TRP Channel Reference Standards Parasite	Cardiovascular Disease
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-N13026

GA12-aldehyde	Endogenous Metabolite	Others
GA12-aldehyde is an endogenous gibberellin biosynthetic intermediate found in developing Pisum sativum (pea) seeds and is virtually inactive in most bioassays .

HY-N19393

(Rac)-Dihydrokaempferol	Drug Derivative	Others
(Rac)-Dihydrokaempferol is a flavonoid compound. (Rac)-Dihydrokaempferol can be isolated from the heartwood of Larix cajanderi Mayr. . (Rac)-Dihydrokaempferol acts as a biosynthetic intermediate .

HY-111670

α-Acetohydroxybutyric acid	Acetolactate Synthase (ALS)	Metabolic Disease
α-Acetohydroxybutyric acid is a metabolic intermediate produced under the catalysis of acetolactate synthase. α-Acetohydroxybutyric acid is generated from 2-oxobutyric acid and converted into 2,3-dihydroxy-3-methylpentanoic acid in the 2-methylbutanol biosynthetic pathway .

HY-N9464

Episterol	Drug Intermediate Fungal	Infection
Episterol is an Ergosterol (HY-N0181) biosynthetic intermediate. Episterol replaces Ergosterol as the major sterol in Saccharomyces cerevisiae Δerg3 mutants, confers resistance to combined lethal and vacuole-disruptive actions of Amphotericin B (HY-B0221) and MC12 (HY-175024) .

HY-N15457

(2R,3S)-3-Isopropylmalic acid	Drug Intermediate	Metabolic Disease
(2R,3S)-3-Isopropylmalic acid (Compound (2R,3S)-3-Isopropylmalate) is an intermediate of the leucine biosynthetic pathway. (2R,3S)-3-Isopropylmalic acid serves as the main endogenous substrate for the Saccharomyces cerevisiae Tmt1 methyltransferase.

Cat. No.	Product Name

HY-L064

Glutamine Metabolism Compound Library	1,690 compounds
Glutamine is an important metabolic fuel that helps rapidly proliferating cells meet the increased demand for ATP, biosynthetic precursors, and reducing agents. Glutamine Metabolism pathway involves the initial deamination of glutamine by glutaminase(GLS), yielding glutamate and ammonia. Glutamate is converted to the TCA cycle intermediate α-ketoglutarate (α-KG) by either glutamate dehydrogenase (GDH) or by the alanine or aspartate transaminases (TAs), to produce both ATP and anabolic carbons for the synthesis of amino acids, nucleotides and lipids. During periods of hypoxia or mitochondrial dysfunction, α-KG can be converted to citrate in a reductive carboxylation reaction catalyzed by IDH2. The newly formed citrate exits the mitochondria where it is used to synthesize fatty acids and amino acids and produce the reducing agent, NADPH. Cancer cells display an altered metabolic circuitry that is directly regulated by oncogenic mutations and loss of tumor suppressors. Mounting evidence indicates that altered glutamine metabolism in cancer cells has critical roles in supporting macromolecule biosynthesis, regulating signaling pathways, and maintaining redox homeostasis, all of which contribute to cancer cell proliferation and survival. Thus, intervention in glutamine metabolic processes could provide novel approaches to improve cancer treatment. MCE owns a unique collection of 1,690 compounds targeting the mainly proteins and enzymes involved in glutamine metabolism pathway. Glutamine Metabolism compound library is a useful tool for intervention in glutamine metabolic processes.

Glutamine Metabolism Compound Library

1,690 compounds

Glutamine is an important metabolic fuel that helps rapidly proliferating cells meet the increased demand for ATP, biosynthetic precursors, and reducing agents. Glutamine Metabolism pathway involves the initial deamination of glutamine by glutaminase(GLS), yielding glutamate and ammonia. Glutamate is converted to the TCA cycle intermediate α-ketoglutarate (α-KG) by either glutamate dehydrogenase (GDH) or by the alanine or aspartate transaminases (TAs), to produce both ATP and anabolic carbons for the synthesis of amino acids, nucleotides and lipids. During periods of hypoxia or mitochondrial dysfunction, α-KG can be converted to citrate in a reductive carboxylation reaction catalyzed by IDH2. The newly formed citrate exits the mitochondria where it is used to synthesize fatty acids and amino acids and produce the reducing agent, NADPH.

Cancer cells display an altered metabolic circuitry that is directly regulated by oncogenic mutations and loss of tumor suppressors. Mounting evidence indicates that altered glutamine metabolism in cancer cells has critical roles in supporting macromolecule biosynthesis, regulating signaling pathways, and maintaining redox homeostasis, all of which contribute to cancer cell proliferation and survival. Thus, intervention in glutamine metabolic processes could provide novel approaches to improve cancer treatment.

MCE owns a unique collection of 1,690 compounds targeting the mainly proteins and enzymes involved in glutamine metabolism pathway. Glutamine Metabolism compound library is a useful tool for intervention in glutamine metabolic processes.

D-Erythrose (50% in water)	Biochemical Assay Reagents
D-Erythrose is a four-carbon sugar classified as an aldose. D-Erythrose has unique chemical properties that make it an important intermediate in various metabolic pathways, especially in the biosynthesis of amino acids and nucleotides. It also plays a role in the pentose phosphate pathway, which generates reducing equivalents for biosynthetic reactions and cellular defense against oxidative damage.

Cat. No.	Product Name	Target	Research Area

HY-P3519

ACV Tripeptide	Drug Intermediate	Infection
ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics .

HY-P3519A

ACV Tripeptide TFA	Drug Intermediate	Infection
ACV Tripeptide TFA, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide TFA is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide TFA can be used for the biosynthesis of β-lactam antibiotics .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1247

Protoporphyrin IX 20+ Cited Publications PPIX	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-116956

D-Erythrose (50% in water)	Source Classification	Biochemical Assay Reagents
D-Erythrose is a four-carbon sugar classified as an aldose. D-Erythrose has unique chemical properties that make it an important intermediate in various metabolic pathways, especially in the biosynthesis of amino acids and nucleotides. It also plays a role in the pentose phosphate pathway, which generates reducing equivalents for biosynthetic reactions and cellular defense against oxidative damage.

HY-N3926

Garbanzol	Structural Classification Flavanonols Flavonoids Plants Toxicodendron vernicifluum (Stokes) F. A. Barkl. Anacardiaceae Source Classification	Drug Intermediate
Garbanzol is an orally active natural flavonoid compound. Garbanzol is one of the key intermediates in the flavonoid biosynthetic pathway. Garbanzol exhibits anti-mutagenic activity .

HY-B1247R

Protoporphyrin IX (Standard) PPIX (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-N1356A

(R)-Reticuline	Structural Classification Alkaloids Plants Lauraceae Isoquinoline Alkaloids Lindera aggregata (Sims) Kosterm. Source Classification	Cytochrome P450
(R)-Reticuline is a key intermediate and precursor in the biosynthetic pathway of morphinan alkaloids. (R)-Reticuline plays a central role in the metabolism of opium poppy (Papaver somniferum). (R)-Reticuline can either undergo O-methylation catalyzed by PSOMT1, or be converted to (+)-Salutaridine via regioselective and stereoselective oxidative coupling under the action of salutaridine synthase (CYP719B1). (R)-Reticuline serves as a direct precursor for the synthesis of important alkaloids such as morphine, codeine and thebaine .

HY-128425A

N-Carbamoyl-L-aspartic acid 1 Publications Verification L-Ureidosuccinic acid	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Fungal
N-Carbamoyl-L-aspartic acid (L-Ureidosuccinic acid) is an important pyrimidine metabolic precursor and intermediate metabolite. N-Carbamoyl-L-aspartic acid reverses the growth inhibition of Ura ⁺ strains induced by 2-thiouracil (with growth rate increasing linearly with its concentration), but fails to support the growth of uracil-requiring Ura ^- strains. N-Carbamoyl-L-aspartic acid inhibits the cell growth of Saccharomyces cerevisiae by suppressing the purine biosynthetic pathway at a pre-step of 5-aminoimidazole nucleotide synthesis. The growth inhibitory effect of N-Carbamoyl-L-aspartic acid on yeast can be alleviated by purines, and the sensitivity of strains is closely related to the activity level of dihydroorotase .

HY-W740803

15-cis-Phytofluene (15Z)-Phytofluene	Natural Products Rosaceae Plants Prunus armeniaca L. Source Classification	Drug Intermediate Drug Isomer
15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis .

HY-N12196

Terretonin	Other Monoterpenes Microorganisms Terpenoids Source Classification	Cytochrome P450
Terretonin is a fungal terpenoid isolated from Aspergillus terreus. The complete biosynthetic pathway of terretonin includes: cytochrome P450 Trt6 catalyzes the oxidation of terrenoid to obtain an unstable intermediate; then it is catalyzed by isomerase Trt14 and processed by non-heme iron-dependent dioxygenase Trt7 to complete the biosynthesis of terretonin .

HY-N14823

Demethylmacrocin	Microorganisms Antibiotics Other Antibiotics Source Classification	Drug Intermediate
Demethylmacrocin is a key intermediate in the biosynthetic pathway of Tylosin (HY-B0519A). Demethylmacrocin can be efficiently converted into tylosin through specific sequential oxidation and methylation reactions .

HY-W016628R

L-Gulono-1,4-lactone (Standard) L-Gulonolactone (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Saccharides Source Classification	Reference Standards Endogenous Metabolite
L-Gulono-1,4-lactone (L-Gulonolactone) (Standard) is the analytical standard of L-Gulono-1,4-lactone. This product is intended for research and analytical applications. L-Gulono-1,4-lactone is a biosynthetic precursor of L-Ascorbic acid (Vitamin C) (HY-B0166). L-Gulono-1,4-lactone can be enzymatically converted to L-Ascorbic acid via the animal uronic acid pathway, while species such as humans lack the key oxidase that catalyzes this step, resulting in the disruption of this pathway and the necessity to obtain Vitamin C from diet. L-Gulono-1,4-lactone is a putative intermediate in an alternative biosynthetic pathway of L-Ascorbic acid in Arabidopsis thaliana.

HY-N16458

FI-3	Structural Classification Natural Products Microorganisms Source Classification	Drug Intermediate
FI-3 is a polycyclic tetramate macrolactam biosynthetic intermediate found in Streptomyces sp. SPB78. FI-3 is promising for research of antibiotics .

HY-W014394R

Vanillyl butyl ether (Standard)	Structural Classification Monophenols other families Phenols Plants Source Classification	TRP Channel Reference Standards Parasite
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-N13026

GA12-aldehyde	Structural Classification Leguminosae Ketones, Aldehydes, Acids Pisum sativum Linn Plants Source Classification	Endogenous Metabolite
GA12-aldehyde is an endogenous gibberellin biosynthetic intermediate found in developing Pisum sativum (pea) seeds and is virtually inactive in most bioassays .

HY-N19393

(Rac)-Dihydrokaempferol	Structural Classification Flavonols Flavonoids Pinaceae Plants Larix gmelinii var. gmelinii Source Classification	Drug Derivative
(Rac)-Dihydrokaempferol is a flavonoid compound. (Rac)-Dihydrokaempferol can be isolated from the heartwood of Larix cajanderi Mayr. . (Rac)-Dihydrokaempferol acts as a biosynthetic intermediate .

HY-N9464

Episterol	Structural Classification Microorganisms Steroids Source Classification	Drug Intermediate Fungal
Episterol is an Ergosterol (HY-N0181) biosynthetic intermediate. Episterol replaces Ergosterol as the major sterol in Saccharomyces cerevisiae Δerg3 mutants, confers resistance to combined lethal and vacuole-disruptive actions of Amphotericin B (HY-B0221) and MC12 (HY-175024) .

HY-N15457

(2R,3S)-3-Isopropylmalic acid	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Drug Intermediate
(2R,3S)-3-Isopropylmalic acid (Compound (2R,3S)-3-Isopropylmalate) is an intermediate of the leucine biosynthetic pathway. (2R,3S)-3-Isopropylmalic acid serves as the main endogenous substrate for the Saccharomyces cerevisiae Tmt1 methyltransferase.

Cat. No.	Product Name	Chemical Structure

HY-178299S

3-Amino-5-hydroxybenzoic acid-13C

3-Amino-5-hydroxybenzoic acid- ¹³C is the ¹³C-labeled 3-Amino-5-hydroxybenzoic acid (HY-W077634). 3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose .

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biosynthetic intermediate

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