76045-71-1
76045-71-1
Chemical Structure
3-Amino-5-hydroxybenzoic acid
Synonym(s): AHBA
- CAS No.: 76045-71-1
- Formula:C7H7NO3
- Molecular Weight:153.14
IUPAC Name: 3-amino-5-hydroxybenzoic acid
InChIKey: QPEJHSFTZVMSJH-UHFFFAOYSA-N
SMILES: O=C(C1=CC(N)=CC(O)=C1)O
Biological Activity: 3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose[1][2].
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3-Amino-5-hydroxybenzoic acid | 99.83% | 3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose. | ||||||||||||||||||||
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3-Amino-5-hydroxybenzoic acid-15N | 3-Amino-5-hydroxybenzoic acid-15N is a 15N-labeled form of 3-Amino-5-hydroxybenzoic acid. | |||||||||||||||||||||
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3-Amino-5-hydroxybenzoic acid-13C | 3-Amino-5-hydroxybenzoic acid-13C is the 13C-labeled 3-Amino-5-hydroxybenzoic acid (HY-W077634). 3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose. | |||||||||||||||||||||
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References
- [1]. Mao Y, et al. Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564. Chem Biol. 1999 Apr;6(4):251-63. [Content Brief]
- [2]. Floss HG, et al. The biosynthesis of 3-amino-5-hydroxybenzoic acid (AHBA), the precursor of mC7N units in ansamycin and mitomycin antibiotics: a review. J Antibiot (Tokyo). 2011 Jan;64(1):35-44. [Content Brief]
