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Results for "

block polymers

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) ADC Antibody (1) ADC Payload (2) Akt (1) Antibiotic (4) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (13) Arp2/3 Complex (4) ATP Synthase (1) Autophagy (3) Bacterial (9) Bcl-2 Family (2) Biochemical Assay Reagents (71) Calcium Channel (1) Carbonic Anhydrase (1) Caspase (1) CD1 (1) CXCR (7) DNA/RNA Synthesis (2) Drug Derivative (1) Drug Intermediate (5) Drug-Linker Conjugates for ADC (1) Endogenous Metabolite (8) Environmental Pollutants (9) Fungal (1) HDAC (2) Herbicide (1) Histamine Receptor (6) HIV (4) Interleukin Related (1) Isotope-Labeled Compounds (8) Ligands for E3 Ligase (1) Liposome (1) MDM-2/p53 (2) Microtubule/Tubulin (17) Mitosis (1) MMP (1) P-glycoprotein (1) Parasite (2) PARP (1) Phosphoramidites (1) PI3K (1) PROTAC Linkers (1) Reactive Oxygen Species (ROS) (2) Reference Standards (5) Reverse Transcriptase (3) RUNX (1) SARS-CoV (1) STAT (2) TNF Receptor (1) Topoisomerase (1)
By Research Areas:	Cancer (37) Endocrinology (4) Infection (17) Inflammation/Immunology (12) Metabolic Disease (2) Neurological Disease (6)
Oligonucleotides:	Pegylated Lipids (1) Polymers (3) Phosphoramidites (1) Guanine (1)

126

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0479

L-Lactic acid 10+ Cited Publications (S)-2-Hydroxypropanoic acid	Environmental Pollutants Antibiotic Endogenous Metabolite Bacterial	Infection Cancer
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid has antiproliferative activity .

HY-16928

Cytochalasin B Maximum Cited Publications 45 Publications Verification Phomin	Arp2/3 Complex	Cancer
Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with K_d value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.

HY-W040233

L-Lactic acid sodium 10+ Cited Publications (S)-2-Hydroxypropanoic acid sodium	Environmental Pollutants Antibiotic Endogenous Metabolite Drug Intermediate Bacterial	Infection Cancer
L-lactate Sodium (Sodium (S)-2-hydroxypropanoate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity .

HY-16929

Latrunculin A 10+ Cited Publications LAT-A	Arp2/3 Complex	Cancer
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K_ds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .

HY-D1005A22

Poloxamer 338 (F108) PEG-PPG-PEG, 14600 (Average)	Environmental Pollutants Biochemical Assay Reagents	Others
Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats .

HY-15582

Auristatin E	Microtubule/Tubulin ADC Payload	Cancer
Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids .

HY-125527

Resolvin D1 1 Publications Verification RvD1	Endogenous Metabolite	Inflammation/Immunology
Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .

HY-B0294

Flubendazole 5+ Cited Publications	Parasite Microtubule/Tubulin STAT MDM-2/p53 Apoptosis Autophagy	Infection Cancer
Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites .

HY-D1005A2

Poloxamer 105 (L35) PEG-PPG-PEG, 1900 (Average)	Environmental Pollutants Biochemical Assay Reagents	Others
Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900 Da. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A8

Poloxamer 181 (L61) PEG-PPG-PEG, 2000 (Average)	Environmental Pollutants Biochemical Assay Reagents Bacterial P-glycoprotein	Infection Cancer
Poloxamer 181 L61 is a block polymer of polyethylene oxide and polypropylene oxide with an average molecular weight of 2000. Poloxamer has the ability to inhibit P-gp. Poloxamer 181 has antimicrobial activity and can inhibit Mycobacterium avium. Poloxamer 181 can form a thermally reversible hydrogel and is used as a food additive, and as an agent delivery carrier in cosmetics, pharmaceuticals and tissue engineering .

HY-158712

3'-ONH2-dATP sodium solution (100 mM)		Others
3'-ONH2-dATP (sodium) solution (100 mM) is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate.3'-ONH2-dATP (sodium) solution (100 mM) stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension.3'-ONH2-dATP (sodium) solution (100 mM) incorporates into an oligonucleotide chain by engineered terminal deoxynucleotidyl transferase from Zonotrichia albicollis to enable template-free, stepwise de novo enzymatic DNA synthesis .

HY-140697

m-PEG5000-OH mPEG5000-Hydroxy; Polyethylene glycol monomethyl ether 5000	Environmental Pollutants PROTAC Linkers	Cancer
m-PEG5000-OH (mPEG5000-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG1000-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .

HY-140696E

m-PEG1000-OH mPEG1000-Hydroxy; Polyethylene glycol monomethyl ether 1000	Environmental Pollutants Biochemical Assay Reagents	Cancer
m-PEG1000-OH (mPEG1000-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG1000-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .

HY-15892

CK-636 4 Publications Verification CK-0944636	Arp2/3 Complex	Inflammation/Immunology Cancer
CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC₅₀ values of 4 μM, 24 μM and 32 μM for human, fission yeast and bovine, respectively. CK636 blocks cell migration.

HY-W002105

2,5-Furandicarboxylic acid 1 Publications Verification	Endogenous Metabolite Biochemical Assay Reagents	Others
2,5-Furandicarboxylic acid, detected in human urine, is an important renewable biotechnological building block because it serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, plasticizers, fungicides, macrocyclic ligands and other products .

HY-W014410

Mucic acid	Drug Intermediate	Endocrinology
Mucic acid (Galactaric acid) is a building block for polymers. Mucic acid stimulates Runx2 mRNA expression. Mucic acid can be used in polymer synthesis and bone tissue engineering research .

HY-W105423

Methacrylic acid N-hydroxysuccinimide ester NHS-MA	Biochemical Assay Reagents	Others
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels .

HY-W013021

Norbornene	Ligands for E3 Ligase	Others
Norbornene is a cycloolefin and building block for synthesis of porous organic polymeric materials via metathesis, addition, and CANAL polymerization. Norbornene can also be used as an E3 ligase ligand for the synthesis of PROTAC, such as PROTAC HyTTD Degrader-1 (HY-181895) .

HY-B2227BS3

L-Lactic acid-13C-1 sodium (20% w/w in water) L-E-270-13C-1 sodium	Isotope-Labeled Compounds Bacterial Drug Intermediate Endogenous Metabolite	Infection Cancer
L-Lactic acid- ¹³C₁ (L-E-270- ¹³C₁) sodium (20% in water) is the ¹³C-labeled L-Lactic acid sodium (HY-W040233). L-lactate Sodium is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activityy .

HY-155902

Mal-PEG5000-OH Maleimide-PEG5000-Hydroxy	Biochemical Assay Reagents	Others
Mal-PEG5000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-128711

MAL-di-EG-Val-Cit-PAB-MMAF	Drug-Linker Conjugates for ADC	Cancer
MAL-di-EG-Val-Cit-PAB-MMAF consists the ADCs linker (MAL-di-EG-Val-Cit-PAB) and potent tubulin polymerization blocker (MMAF, Monomethyl auristatin F) .

HY-140696B

m-PEG550-OH mPEG550-Hydroxy; Polyethylene glycol monomethyl ether 550	Environmental Pollutants Biochemical Assay Reagents	Cancer
m-PEG550-OH (mPEG550-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG550-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .

HY-144012A

DPPE-PEG350 16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium	Liposome CD1	Others
DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells . DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.

HY-Y0479AS2

L-Lactate-13C sodium (20% in water) 1 Publications Verification (S)-2-Hydroxypropanoic acid-13C sodium	Isotope-Labeled Compounds Drug Intermediate Antibiotic Bacterial Endogenous Metabolite	Infection Cancer
L-Lactate- ¹³C ((S)-2-Hydroxypropanoic acid- ¹³C) sodium is the ¹³C-labeled L-Lactic acid sodium (HY-W040233). L-lactate Sodium is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity .

HY-W040233R

L-Lactic acid sodium (Standard) (S)-2-Hydroxypropanoic acid sodium (Standard)	Bacterial Reference Standards	Infection Cancer
Sodium (S)-2-hydroxypropanoate (Standard) is the analytical standard of Sodium (S)-2-hydroxypropanoate. This product is intended for research and analytical applications. L-lactate Sodium (Sodium (S)-2-hydroxypropanoate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity .

HY-N6701

Dihydrocytochalasin B	Arp2/3 Complex DNA/RNA Synthesis Calcium Channel	Inflammation/Immunology
Dihydrocytochalasin B is an Actin disruptor. Dihydrocytochalasin B disrupts actin microfilament bundles, inhibits actin polymerization, and alters intracellular actin cytoskeletal structures. Dihydrocytochalasin B blocks the initiation of DNA synthesis. Dihydrocytochalasin B inhibits Calcium transport. Dihydrocytochalasin B inhibits cytokinesis and alters cell morphology. Dihydrocytochalasin B can be used in studies related to rickets .

HY-P99705

Lifastuzumab vedotin RG-7599; DNIB-0600A; NaPi2b-ADC	Antibody-Drug Conjugates (ADCs)	Cancer
Lifastuzumab vedotin (RG-7599; DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a potent antimitotic agent, monomethyl auristatin E (MMAE), which inhibits cell division by blocking the polymerization of tubulin. Lifastuzumab vedotin has the potential for non-small cell lung cancer (NSCLC) and platinum-resistant ovarian cancer (PROC) research .

HY-140696H

m-PEG750-OH mPEG750-Hydroxy; Polyethylene glycol monomethyl ether 750	Biochemical Assay Reagents	Cancer
m-PEG750-OH (mPEG750-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG750-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .

HY-155902A

Mal-PEG2000-OH Maleimide-PEG2000-Hydroxy	Biochemical Assay Reagents	Others
Mal-PEG2000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-Y1219E

Silica gel, high-purity grade, 130-270 mesh	Biochemical Assay Reagents	Others
Silica gel, high-purity grade, 130-270 mesh is a high-purity inert additive with low density and large specific surface area, which can be used in the preparation of chromatographic column frits based on the sol-gel method. As a condensed-phase flame retardant, thermal stability enhancer and melt viscosity enhancer, Silica gel, high-purity grade, 130-270 mesh can restrict the mobility of polymer chains in polypropylene to improve its thermal stability, and increase the melt viscosity of polypropylene and polyethylene oxide. During gasification or combustion, Silica gel, high-purity grade, 130-270 mesh accumulates on the polymer surface to form a thermal insulation layer, and exerts flame retardant effects by reducing surface concentration and blocking the transport of degradation products .

HY-170505

Icafolin-methyl	Microtubule/Tubulin Herbicide	Others
Icafolin-methyl is a herbicide and plant β-tubulin (Microtubule/Tubulin) inhibitor. Icafolin-methyl binds to the β-tubulin region of the Colchicine (HY-16569) binding site, thereby blocking the polymerization of plant tubulin. As a non-selective herbicide, Icafolin-methyl exhibits post-emergence activity against weeds in both cool-season and warm-season cropping systems, including resistant ryegrass and darnel biotypes. Icafolin-methyl can be used for herbicide research .

HY-W250580

Dimethicone	Biochemical Assay Reagents	Others
Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products .

HY-D1005A7

Poloxamer 125 (L45) PEG-PPG-PEG, 2400 (Average)	Biochemical Assay Reagents	Others
Poloxamer 125 L45 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2400. Poloxamer 125 L45 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A4

Poloxamer 122 (L42) PEG-PPG-PEG, 1630 (Average)	Biochemical Assay Reagents Bacterial	Infection
Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-125527S

Resolvin D1-d5 RvD1-d₅	Isotope-Labeled Compounds Endogenous Metabolite	Inflammation/Immunology
Resolvin D1-d₅ is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .

HY-172378

Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000)	Biochemical Assay Reagents	Others
Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000) is a diblock copolymer used to prepare polymer micelles or vesicles and other encapsulation applications .

HY-147768

PI3K/AKT-IN-2	PI3K Akt Microtubule/Tubulin MMP Apoptosis	Cancer
PI3K/AKT-IN-2 (Compound 12c) is a PI3K and AKT inhibitor. PI3K/AKT-IN-2 blocks the epithelial-mesenchymal transition (EMT) and induces apoptosis. PI3K/AKT-IN-2 inhibits the polymerization of tubulin .

HY-W105639

L-Lactic acid calcium hydrate 10+ Cited Publications	Drug Intermediate	Others
L-Lactic acid calcium hydrate is the calcium salt of L-Lactic acid. L-Lactic acid calcium hydrate is a building block that can be used as a precursor for the production of bioplastic polymer polylactic acid .

HY-155902B

Mal-PEG1000-OH Maleimide-PEG1000-Hydroxy	Biochemical Assay Reagents	Others
Mal-PEG1000-OH was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-W087964

Dodecanedioyl dichloride	Biochemical Assay Reagents	Others
Dodecanedioyl dichloride, Dodecanedioyl dichloride is commonly used in organic synthesis as a general building block for the preparation of various polymers and plastics, including nylon 12 and polyester resins, it can be used to introduce acid chloride groups into other organic molecules, which can then be further reaction to form more complex compounds, moreover, it has been used in medicinal chemistry as a starting material for the synthesis of various drugs and drug candidates.

HY-175021

HDAC-IN-91	HDAC Carbonic Anhydrase Microtubule/Tubulin PARP Apoptosis Bcl-2 Family Caspase	Cancer
HDAC-IN-91 is a multiple inhibitor of HDAC (IC₅₀ = 134.22 nM for HDAC1, 66.29 nM for HDAC2), carbonic anhydrase (CA) (K_i = 72.03 nM for CA IX, 50.76 nM for XII), and tubulin polymerization ( IC₅₀ = 2.56 μM). HDAC-IN-91 inhibits PARP1 and increases the Bax/Bcl-2 ratio. HDAC-IN-91 blocks the cell cycle at the G2/M phase and induces apoptosis through a mitochondrial apoptosis activation mechanism. HDAC-IN-91 can exert potent cytotoxic activity through tubulin polymerization inhibition. HDAC-IN-91 can be used in breast, colorectal, cervical and lung cancer research .

HY-155902C

Mal-PEG3400-OH Maleimide-PEG3400-Hydroxy	Biochemical Assay Reagents	Others
Mal-PEG3400-OH (Maleimide-PEG3400-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG3400-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-161338

Tubulin polymerization-IN-61	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-61 (Compound 9a) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-61 destroys the microtubule skeleton, blocks the cell cycle in G2/M phase, induces Apoptosis, and inhibits cancer cell migration and colony formation. Tubulin polymerization-IN-61 shows antitumor activity in vivo against 4T1 xenograft model .

HY-W014410R

Mucic acid (Standard)	Reference Standards Biochemical Assay Reagents RUNX	Endocrinology
Mucic acid (Standard) is the analytical standard of Mucic acid (HY-W014410). This product is intended for research and analytical applications. Mucic acid (Galactaric acid) is a building block for polymers. Mucic acid stimulates Runx2 mRNA expression. Mucic acid can be used in polymer synthesis and bone tissue engineering research .

HY-167357

PLLA3000-PEG1000-PLLA3000	Biochemical Assay Reagents	Others
PLLA3000-PEG1000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG1000-PLLA3000 can be used in drug delivery research .

HY-167118

PLLA5000-PEG6000-PLLA5000	Biochemical Assay Reagents	Others
PLLA5000-PEG6000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG6000-PLLA5000 can be used in drug delivery research .

HY-167352

PLLA3000-PEG8000-PLLA3000	Biochemical Assay Reagents	Others
PLLA3000-PEG8000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG8000-PLLA3000 can be used in drug delivery research .

HY-167366

PLLA1000-PEG4000-PLLA1000	Biochemical Assay Reagents	Others
PLLA1000-PEG4000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG4000-PLLA1000 can be used in drug delivery research .

HY-167346

PLLA4000-PEG8000-PLLA4000	Biochemical Assay Reagents	Others
PLLA4000-PEG8000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG8000-PLLA4000 can be used in drug delivery research .

HY-167359

PLLA2000-PEG6000-PLLA2000	Biochemical Assay Reagents	Others
PLLA2000-PEG6000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG6000-PLLA2000 can be used in drug delivery research .

Cat. No.	Product Name	Type

HY-D1005A22

Poloxamer 338 (F108) PEG-PPG-PEG, 14600 (Average)	Biochemical Assay Reagents
Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats .

HY-D1005A6

Poloxamer 124 (L44)

PEG-PPG-PEG, 2200 (Average)

Biochemical Assay Reagents

Poloxamer 124 L44 is a block polymer of polyoxyethylene and polyoxypropylene and a hydrophobic surfactant. Poloxamer 124 L44 causes eye irritation and exhibits oral toxicity in albino rats with an LD₅₀ of 5 g/kg. Poloxamer 124 L44 has reversible adverse effects on triglyceride and cholesterol transport in the lymphatic system of rats. Poloxamer 124 L44 can form thermoreversible hydrogels and is used as a food additive and as a drug delivery vehicle in cosmetics, pharmaceuticals, and tissue engineering[1][2][3].

HY-D1005A2

Poloxamer 105 (L35) PEG-PPG-PEG, 1900 (Average)	Biochemical Assay Reagents
Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900 Da. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A8

Poloxamer 181 (L61)

PEG-PPG-PEG, 2000 (Average)

Biochemical Assay Reagents

Poloxamer 181 L61 is a block polymer of polyethylene oxide and polypropylene oxide with an average molecular weight of 2000. Poloxamer has the ability to inhibit P-gp. Poloxamer 181 has antimicrobial activity and can inhibit Mycobacterium avium. Poloxamer 181 can form a thermally reversible hydrogel and is used as a food additive, and as an agent delivery carrier in cosmetics, pharmaceuticals and tissue engineering .

HY-158712

3'-ONH2-dATP sodium solution (100 mM)

Biochemical Assay Reagents

3'-ONH2-dATP (sodium) solution (100 mM) is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate.3'-ONH2-dATP (sodium) solution (100 mM) stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension.3'-ONH2-dATP (sodium) solution (100 mM) incorporates into an oligonucleotide chain by engineered terminal deoxynucleotidyl transferase from Zonotrichia albicollis to enable template-free, stepwise de novo enzymatic DNA synthesis .

HY-140696E

m-PEG1000-OH mPEG1000-Hydroxy; Polyethylene glycol monomethyl ether 1000	Biochemical Assay Reagents
m-PEG1000-OH (mPEG1000-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG1000-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .

HY-W105423

Methacrylic acid N-hydroxysuccinimide ester NHS-MA	Biochemical Assay Reagents
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels .

HY-155902

Mal-PEG5000-OH Maleimide-PEG5000-Hydroxy	Biochemical Assay Reagents
Mal-PEG5000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-140696B

m-PEG550-OH mPEG550-Hydroxy; Polyethylene glycol monomethyl ether 550	Biochemical Assay Reagents
m-PEG550-OH (mPEG550-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG550-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .

HY-144012A

DPPE-PEG350 16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium	Biochemical Assay Reagents
DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells . DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.

HY-140696H

m-PEG750-OH mPEG750-Hydroxy; Polyethylene glycol monomethyl ether 750	Biochemical Assay Reagents
m-PEG750-OH (mPEG750-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG750-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery .

HY-155902A

Mal-PEG2000-OH Maleimide-PEG2000-Hydroxy	Biochemical Assay Reagents
Mal-PEG2000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-Y1219E

Silica gel, high-purity grade, 130-270 mesh

Biochemical Assay Reagents

Silica gel, high-purity grade, 130-270 mesh is a high-purity inert additive with low density and large specific surface area, which can be used in the preparation of chromatographic column frits based on the sol-gel method. As a condensed-phase flame retardant, thermal stability enhancer and melt viscosity enhancer, Silica gel, high-purity grade, 130-270 mesh can restrict the mobility of polymer chains in polypropylene to improve its thermal stability, and increase the melt viscosity of polypropylene and polyethylene oxide. During gasification or combustion, Silica gel, high-purity grade, 130-270 mesh accumulates on the polymer surface to form a thermal insulation layer, and exerts flame retardant effects by reducing surface concentration and blocking the transport of degradation products .

HY-D1005A7

Poloxamer 125 (L45) PEG-PPG-PEG, 2400 (Average)	Biochemical Assay Reagents
Poloxamer 125 L45 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2400. Poloxamer 125 L45 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A4

Poloxamer 122 (L42)

PEG-PPG-PEG, 1630 (Average)

Biochemical Assay Reagents

Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-116282W

Dextran sulfate sodium salt (MW 6500-10000)

DSS (MW 6500-10000); DXS (MW 6500-10000)

Biochemical Assay Reagents

Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 ^⁺ T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .

HY-172378

Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000)	Biochemical Assay Reagents
Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000) is a diblock copolymer used to prepare polymer micelles or vesicles and other encapsulation applications .

HY-155902B

Mal-PEG1000-OH Maleimide-PEG1000-Hydroxy	Biochemical Assay Reagents
Mal-PEG1000-OH was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-W087964

Dodecanedioyl dichloride

Biochemical Assay Reagents

Dodecanedioyl dichloride, Dodecanedioyl dichloride is commonly used in organic synthesis as a general building block for the preparation of various polymers and plastics, including nylon 12 and polyester resins, it can be used to introduce acid chloride groups into other organic molecules, which can then be further reaction to form more complex compounds, moreover, it has been used in medicinal chemistry as a starting material for the synthesis of various drugs and drug candidates.

HY-155902C

Mal-PEG3400-OH Maleimide-PEG3400-Hydroxy	Biochemical Assay Reagents
Mal-PEG3400-OH (Maleimide-PEG3400-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG3400-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-167357

PLLA3000-PEG1000-PLLA3000	Biochemical Assay Reagents
PLLA3000-PEG1000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG1000-PLLA3000 can be used in drug delivery research .

HY-167118

PLLA5000-PEG6000-PLLA5000	Biochemical Assay Reagents
PLLA5000-PEG6000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG6000-PLLA5000 can be used in drug delivery research .

HY-167352

PLLA3000-PEG8000-PLLA3000	Biochemical Assay Reagents
PLLA3000-PEG8000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG8000-PLLA3000 can be used in drug delivery research .

HY-167366

PLLA1000-PEG4000-PLLA1000	Biochemical Assay Reagents
PLLA1000-PEG4000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG4000-PLLA1000 can be used in drug delivery research .

HY-167346

PLLA4000-PEG8000-PLLA4000	Biochemical Assay Reagents
PLLA4000-PEG8000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG8000-PLLA4000 can be used in drug delivery research .

HY-167359

PLLA2000-PEG6000-PLLA2000	Biochemical Assay Reagents
PLLA2000-PEG6000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG6000-PLLA2000 can be used in drug delivery research .

HY-167351

PLLA4000-PEG1000-PLLA4000	Biochemical Assay Reagents
PLLA4000-PEG1000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG1000-PLLA4000 can be used in drug delivery research .

HY-167347

PLLA4000-PEG6000-PLLA4000	Biochemical Assay Reagents
PLLA4000-PEG6000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG6000-PLLA4000 can be used in drug delivery research .

HY-172378A

Poly(styrene)-block-poly(acrylic acid) (PS:PAA 3,000:5,000,DDMAT terminated)	Biochemical Assay Reagents
Poly(styrene)-block-poly(acrylic acid) (PS:PAA 3,000:5,000,DDMAT terminated) is a diblock copolymer used to prepare polymer micelles or vesicles and other encapsulation applications .

HY-155902D

Mal-PEG10000-OH Maleimide-PEG10000-Hydroxy	Biochemical Assay Reagents
Mal-PEG10000-OH (Maleimide-PEG10000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG10000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .

HY-182662

Polymer blocking agent CA2000	Biochemical Assay Reagents
Polymer blocking agent CA2000 is a polymer blocking agent composed of long PEG chains and terminal short amino groups. Polymer blocking agent CA2000 effectively reduces non-specific adsorption, significantly improving the accuracy and reliability of detection.

HY-182662A

Polymer blocking agent CA4000	Biochemical Assay Reagents
Polymer blocking agent CA4000 is a polymer blocking agent composed of long PEG chains and terminal short amino groups. Polymer blocking agent CA4000 effectively reduces non-specific adsorption, significantly improving the accuracy and reliability of detection.

HY-167343

PLLA5000-PEG3000-PLLA5000	Biochemical Assay Reagents
PLLA5000-PEG3000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG3000-PLLA5000 can be used in drug delivery research .

HY-167363

PLLA2000-PEG1000-PLLA2000	Biochemical Assay Reagents
PLLA2000-PEG1000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG1000-PLLA2000 can be used in drug delivery research .

HY-167137

PLLA6000-PEG6000-PLLA6000	Biochemical Assay Reagents
PLLA6000-PEG6000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG6000-PLLA6000 can be used in drug delivery research .

HY-167128

PLLA8000-PEG8000-PLLA8000	Biochemical Assay Reagents
PLLA8000-PEG8000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG8000-PLLA8000 can be used in drug delivery research .

HY-167132

PLLA6000-PEG4000-PLLA6000	Biochemical Assay Reagents
PLLA6000-PEG4000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG4000-PLLA6000 can be used in drug delivery research .

HY-167356

PLLA3000-PEG2000-PLLA3000	Biochemical Assay Reagents
PLLA3000-PEG2000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG2000-PLLA3000 can be used in drug delivery research .

HY-167139

PLLA8000-PEG1000-PLLA8000	Biochemical Assay Reagents
PLLA8000-PEG1000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG1000-PLLA8000 can be used in drug delivery research .

HY-167360

PLLA2000-PEG4000-PLLA2000	Biochemical Assay Reagents
PLLA2000-PEG4000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG4000-PLLA2000 can be used in drug delivery research .

HY-167126

PLLA6000-PEG3000-PLLA6000	Biochemical Assay Reagents
PLLA6000-PEG3000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG3000-PLLA6000 can be used in drug delivery research .

HY-167365

PLLA1000-PEG6000-PLLA1000	Biochemical Assay Reagents
PLLA1000-PEG6000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG6000-PLLA1000 can be used in drug delivery research .

HY-167345

PLLA5000-PEG1000-PLLA5000	Biochemical Assay Reagents
PLLA5000-PEG1000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG1000-PLLA5000 can be used in drug delivery research .

HY-167353

PLLA3000-PEG6000-PLLA3000	Biochemical Assay Reagents
PLLA3000-PEG6000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG6000-PLLA3000 can be used in drug delivery research .

HY-167350

PLLA4000-PEG2000-PLLA4000	Biochemical Assay Reagents
PLLA4000-PEG2000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG2000-PLLA4000 can be used in drug delivery research .

HY-167134

PLLA8000-PEG4000-PLLA8000	Biochemical Assay Reagents
PLLA8000-PEG4000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG4000-PLLA8000 can be used in drug delivery research .

HY-167120

PLLA6000-PEG1000-PLLA6000	Biochemical Assay Reagents
PLLA6000-PEG1000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG1000-PLLA6000 can be used in drug delivery research .

HY-167358

PLLA2000-PEG8000-PLLA2000	Biochemical Assay Reagents
PLLA2000-PEG8000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG8000-PLLA2000 can be used in drug delivery research .

HY-167367

PLLA1000-PEG3000-PLLA1000	Biochemical Assay Reagents
PLLA1000-PEG3000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG3000-PLLA1000 can be used in drug delivery research .

HY-167344

PLLA5000-PEG2000-PLLA5000	Biochemical Assay Reagents
PLLA5000-PEG2000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG2000-PLLA5000 can be used in drug delivery research .

Cat. No.	Product Name	Target	Research Area

HY-116073

L-Penicillamine	Acyltransferase	Infection Cancer
L-Penicillamine is an orally active serine palmitoyltransferase (SPT) inhibitor. L-Penicillamine inactivates the PLP cofactor by forming adducts, thereby inhibiting SPT activity and reducing sphingolipid biosynthesis. L-Penicillamine not only blocks tumor access to vitamin B6, but also stabilizes the human papillomavirus 16 E6 oncoprotein monomer and inhibits its polymerization, exhibiting a unique anticancer mechanism. L-Penicillamine effectively delays the growth of Sarcoma-180, induces tumor necrosis and prolongs survival (though long-term use may lead to Pyridoxine (HY-B1328) deficiency and weight loss) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P9980

Belantamab 2 Publications Verification GSK2857914	ADC Antibody TNF Receptor	Cancer
Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma .

HY-P992439

PF-06747143	CXCR	Cancer
PF-06747143 is recombinant anti-human antibody targeting CXCR4. PF-06747143 blocks CXCL12-induced calcium flux, F-actin polymerization, chemotaxis, cell migration, and leukemic cell bone marrow homing. PF-06747143 reduces tumor burden and improves survival in mouse models of hematologic malignancies. PF-06747143 can be used for the research of chronic lymphocytic leukemia, acute myeloid leukemia, and hematologic malignancies .

HY-P992382

IC 100	Interleukin Related	Neurological Disease Inflammation/Immunology
IC 100 is a humanized IgG4κ monoclonal antibody targeting apoptosis-associated speck-like protein (ASC) with blood-brain barrier permeability. IC 100 specifically inhibits ASC after being endocytosed via its Fc segment, blocks ASC polymerization and inflammasome activation, suppresses IL-1β release, forms complexes with ASC and TRIM21, and evades TRIM21-mediated proteasomal degradation. IC 100 alleviates symptoms associated with autoimmune encephalomyelitis, reduces immune cell infiltration and microglial activation in the mouse EAE model. IC 100 is suitable for research on neuroinflammatory and inflammasome-related diseases such as multiple sclerosis. Isotype comparison: HY-P99003 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0479

L-Lactic acid 10+ Cited Publications (S)-2-Hydroxypropanoic acid	Structural Classification Classification of Application Fields Endocrine diseases Endogenous metabolite Infection Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder Source Classification	Environmental Pollutants Antibiotic Endogenous Metabolite Bacterial
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid has antiproliferative activity .

HY-16928

Cytochalasin B Maximum Cited Publications 45 Publications Verification Phomin	Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification Cancer	Arp2/3 Complex
Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with K_d value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.

HY-16929

Latrunculin A 10+ Cited Publications LAT-A	Macrolide Antibiotics Animals Classification of Application Fields Antibiotics Marine natural products Other Diseases Sponge Disease Research Anticancer Disease Research Fields Source Classification	Arp2/3 Complex
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K_ds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .

HY-125527

Resolvin D1 1 Publications Verification RvD1	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology Source Classification	Endogenous Metabolite
Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .

HY-W002105

2,5-Furandicarboxylic acid 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Biochemical Assay Reagents
2,5-Furandicarboxylic acid, detected in human urine, is an important renewable biotechnological building block because it serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, plasticizers, fungicides, macrocyclic ligands and other products .

HY-W014410

Mucic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Drug Intermediate
Mucic acid (Galactaric acid) is a building block for polymers. Mucic acid stimulates Runx2 mRNA expression. Mucic acid can be used in polymer synthesis and bone tissue engineering research .

HY-W013021

Norbornene	Structural Classification Natural Products Mangifera pajang Kosterm. Plants Anacardiaceae Source Classification	Ligands for E3 Ligase
Norbornene is a cycloolefin and building block for synthesis of porous organic polymeric materials via metathesis, addition, and CANAL polymerization. Norbornene can also be used as an E3 ligase ligand for the synthesis of PROTAC, such as PROTAC HyTTD Degrader-1 (HY-181895) .

HY-B0426A

Olopatadine hydrochloride ALO4943A; KW4679	Structural Classification Alkaloids Classification of Application Fields Ketones, Aldehydes, Acids Other Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Histamine Receptor CXCR
Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-W062109

Olopatadine	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Histamine Receptor CXCR
Olopatadine (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-B0426AR

Olopatadine hydrochloride (Standard) ALO4943A (Standard); KW4679 (Standard)	Structural Classification Alkaloids Ketones, Aldehydes, Acids Other Alkaloids Endogenous metabolite Source Classification	Reference Standards Histamine Receptor CXCR
Olopatadine (hydrochloride) (Standard) is the analytical standard of Olopatadine (hydrochloride). This product is intended for research and analytical applications. Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-W014410R

Mucic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Biochemical Assay Reagents RUNX
Mucic acid (Standard) is the analytical standard of Mucic acid (HY-W014410). This product is intended for research and analytical applications. Mucic acid (Galactaric acid) is a building block for polymers. Mucic acid stimulates Runx2 mRNA expression. Mucic acid can be used in polymer synthesis and bone tissue engineering research .

HY-N14734

Disorazol A	Natural Products Microorganisms Source Classification	Apoptosis Fungal Microtubule/Tubulin Mitosis
Disorazol A1 is an tubulin inhibitor with antifungal activity. Disorazol A1 functions by inhibiting tubulin polymerization, interfering with microtubule formation, blocking mitosis, thus arresting the cell cycle at the G₂/M phase and inducing apoptosis. Disorazol A1 also exhibits an inhibitory effect against L929 mouse fibroblasts with an IC₅₀ value of 3 pM. Disorazol A1 causes the accumulation of p53 protein in the cell nucleus. Disorazol A1 is promising for research of cancers .

HY-154871

α-D-Glucosamine 1-phosphate	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Drug Derivative Biochemical Assay Reagents
α-D-Glucosamine 1-phosphate is a glycosyl donor analog of Glc-1-P. α-D-Glucosamine 1-phosphate acts as a glycosyl donor to produce α(1→4)-linked glucosamine chains in the enzyme-catalyzed polymerization reaction mediated by thermostable α-glucan phosphorylase. α-D-Glucosamine 1-phosphate serves as a glycosyl donor analog to generate a pentasaccharide with a glucosamine residue at the non-reducing end in the maltotetraose glucosamination reaction catalyzed by potato α-glucan phosphorylase. α-D-Glucosamine 1-phosphate is used for the synthesis of amphiphilic block polysaccharides with pH-responsive assembly/disassembly properties .

Cat. No.	Product Name	Chemical Structure

HY-B2227BS3

L-Lactic acid-13C-1 sodium (20% w/w in water)
L-Lactic acid- ¹³C₁ (L-E-270- ¹³C₁) sodium (20% in water) is the ¹³C-labeled L-Lactic acid sodium (HY-W040233). L-lactate Sodium is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activityy .

HY-Y0479AS2

L-Lactate-13C sodium (20% in water) 1 Publications Verification
L-Lactate- ¹³C ((S)-2-Hydroxypropanoic acid- ¹³C) sodium is the ¹³C-labeled L-Lactic acid sodium (HY-W040233). L-lactate Sodium is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity .

HY-15582S

Auristatin E-d8

Auristatin E-d₈ is the deuterium labeled Auristatin E (HY-15582). Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids .

HY-125527S

Resolvin D1-d5

Resolvin D1-d₅ is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .

HY-W062109S

Olopatadine-d6

Olopatadine-d₆ is the deuterium labeled Olopatadine. Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-B0426AS

Olopatadine-d3 hydrochloride

Olopatadine-d₃ hydrochloride (ALO4943A-d₃) is the deuterium labeled Olopatadine hydrochloride. Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-Y0479S3

L-Lactic acid-2-13C1
L-Lactic acid-2- ¹³C₁ is the ¹³C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid .

HY-B0426AS2

Olopatadine-d6 hydrochloride

Olopatadine-d₆ (ALO4943A-d₆; KW4679-d₆) hydrochloride is deuterium-labeled Olopatadine (hydrochloride) (HY-B0426A). Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

Cat. No.	Product Name		Classification

HY-155902

Mal-PEG5000-OH Maleimide-PEG5000-Hydroxy		Polymers
Mal-PEG5000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-144012A

DPPE-PEG350 16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium		Pegylated Lipids
DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells . DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.

HY-155902A

Mal-PEG2000-OH Maleimide-PEG2000-Hydroxy		Polymers
Mal-PEG2000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-W250580

Dimethicone		Others
Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products .

HY-155902B

Mal-PEG1000-OH Maleimide-PEG1000-Hydroxy		Polymers
Mal-PEG1000-OH was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-W800446

LNA-Guanosine 3'-CE phosphoramidite Lna-g amidite		Phosphoramidites Guanine
LNA-Guanosine 3'-CE phosphoramidite (Lna-g amidite) is an essential building block to Locked Nucleic Acid (LNA) oligonucleotide synthesis, which includes a ribonucleoside linked by a methylene unit between the 2’-oxygen and 4’-carbon atoms, paralleling DNA polymer assembly.

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block polymers

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