442632-72-6
Chemical Structure
CK-636
Synonym(s): CK-0944636
- CAS No.: 442632-72-6
- Formula:C16H16N2OS
- Molecular Weight:284.38
IUPAC Name: N-(2-(2-methyl-1H-indol-3-yl)ethyl)thiophene-2-carboxamide
InChIKey: ACAKNPKRLPMONU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CS1)NCCC2=C(C)NC3=C2C=CC=C3
Biological Activity: CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC50 values of 4 μM, 24 μM and 32 μM for human, fission yeast and bovine, respectively. CK636 blocks cell migration.
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CK-636 | 99.94% | CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC50 values of 4 μM, 24 μM and 32 μM for human, fission yeast and bovine, respectively. CK636 blocks cell migration. | ||||||||||||||||||||
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Keywords