Methacrylic acid N-hydroxysuccinimide ester
Based on 1 Customer Validation
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels.
For research use only. We do not sell to patients.
- Purity: 99.99%
- CAS No.: 38862-25-8
- Formula: C8H9NO4
- Molecular Weight:183.16
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Methacrylic acid N-hydroxysuccinimide ester is a polymer that serves as a monomer to prepare biodegradable amphiphilic block copolymer microparticles via RAFT polymerization for pH-triggered drug delivery under acidic conditions, and can also be used for nanogel synthesis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 38862-25-8
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Appearance Solid
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Molecular Weight 183.16
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Formula C8H9NO4
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Color Off-white to light yellow
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SMILES
C=C(C)C(=O)ON1C(=O)CCC1=O
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Synonyms
NHS-MA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (545.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.4597 mL | 27.2985 mL | 54.5971 mL | 136.4927 mL |
| 5 mM | 1.0919 mL | 5.4597 mL | 10.9194 mL | 27.2985 mL | |
| 10 mM | 0.5460 mL | 2.7299 mL | 5.4597 mL | 13.6493 mL | |
| 15 mM | 0.3640 mL | 1.8199 mL | 3.6398 mL | 9.0995 mL | |
| 20 mM | 0.2730 mL | 1.3649 mL | 2.7299 mL | 6.8246 mL | |
| 25 mM | 0.2184 mL | 1.0919 mL | 2.1839 mL | 5.4597 mL | |
| 30 mM | 0.1820 mL | 0.9100 mL | 1.8199 mL | 4.5498 mL | |
| 40 mM | 0.1365 mL | 0.6825 mL | 1.3649 mL | 3.4123 mL | |
| 50 mM | 0.1092 mL | 0.5460 mL | 1.0919 mL | 2.7299 mL | |
| 60 mM | 0.0910 mL | 0.4550 mL | 0.9100 mL | 2.2749 mL | |
| 80 mM | 0.0682 mL | 0.3412 mL | 0.6825 mL | 1.7062 mL | |
| 100 mM | 0.0546 mL | 0.2730 mL | 0.5460 mL | 1.3649 mL |