38 Results for "

confocal

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "confocal" in MCE Product Catalog:

81
81 Publications Verification
Cat. No.: HY-116215
CAS No.: 186689-07-6
Purity:  99.74%
2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
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21
21 Cited Publications
Cat. No.: HY-D0090
CAS No.: 162558-52-3
MQAE is a chloride ion (Cl -) fluorescent probe that can be used to measure chloride concentrations. The fluorescence intensity of MQAE decreases proportionally as Cl - ions increase. MQAE has high cell permeability and is suitable for fluorescence detection such as confocal microscopy and flow cytometry (Ex/Em=350/460 nm) .
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3
3 Cited Publications
Cat. No.: HY-D0333
CAS No.: 2610-10-8
Synonyms: Sirius Red
Direct Red 80 (Sirius Red) is a polyazo dye used principally in staining methods for collagen and amyloid. Direct Red 80 does not release benzidine upon degradation and is safer than many traditional direct dyes .
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1
1 Cited Publications
Cat. No.: HY-D1540
CAS No.: 2097714-45-7
Synonyms: Cy 5.5 amine; Lumiprobe Cy 5.5 amine
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
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1
1 Cited Publications
Cat. No.: HY-NP163C
Synonyms: WGA-AF555
Wheat germ agglutinin-AF555 (WGA-AF555) is a membrane-staining lectin conjugate that combines wheat germ agglutinin with the Alexa Fluor 555 fluorescent dye. Wheat germ agglutinin-AF555 is used for precise staining and contour delineation of cell membranes. Wheat germ agglutinin-AF555 also effectively distinguishes between surface vimentin and intracellular vimentin in cells .
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1
1 Cited Publications
Cat. No.: HY-146245F
Purity:  98.03%
Research Areas:  

Inflammation/Immunology Cancer

FAM-labeled ODN 1826 sodium, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. FAM-labeled ODN 1826 sodium can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy or flow cytometry.
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Cat. No.: HY-D0996
CAS No.: 181885-68-7
Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 has a high affinity for DNA and fluorescence is enhanced after binding, but the maximum emission wavelength is 670nm. Lds-751 and Thiazole orange can be used for the differentiation of red blood cells, platelets, reticulocytes, and nucleated cells and can be stimulated at 488nm. Studies have shown that LDS-751 binds almost exclusively to mitochondria when incubated with nucleated living cells. After nucleated Acridine Orange (HY-101879) staining and LDS-751 treatment of cells, confocal microscopy revealed almost no co-location of the cells. Staining with Rhodamine 123 (HY-D0816), a dye known to bind polarized mitochondria, was almost identical to the pattern observed with LDS-751 .
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Cat. No.: HY-D0154
CAS No.: 80724-20-5
Synonyms: Tetramethylrhodamine-6-isothiocyanate
6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells .
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Cat. No.: HY-DY1019
CAS No.: 186689-07-6
2-NBDG (solution) is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
Solvent and Concentration: Sterile PBS: 5 mM
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Cat. No.: HY-D1459
CAS No.: 164106-16-5
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven llipid peroxidation (Ex/Em=665/676 nm) .
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Cat. No.: HY-W923198
CAS No.: 480439-15-4
Synonyms: Methacryloyloxy fluorescein
Fluorescein O-methacrylate (Methacryloyloxy fluorescein) is a pH-responsive fluorescent monomeric dye. Fluorescein O-methacrylate exhibits pH-responsive fluorescence properties: its fluorescence is activated under alkaline conditions and quenched under neutral or acidic conditions; reversible switching of fluorescence is achievable by adjusting the pH of the solution. Fluorescein O-methacrylate can be used as a monomer for the synthesis of amphiphilic fluorescein polymers. These polymers can self-assemble into stable polymer nanoparticles with enhanced aqueous-phase fluorescence, and also enable the conjugation of nanoparticles with amine-containing biomolecules to support sensitive optical detection of biomarkers (Ex/Em = 490/520 nm) .
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Cat. No.: HY-NP163A
Synonyms: WGA-AF488
Wheat germ agglutinin-AF488 (WGA-AF488) is a cell membrane-specific staining agent prepared by conjugating wheat germ agglutinin with the Alexa Fluor 488 (HY-D1304) fluorescent dye, and it binds to cell surface glycoproteins with high affinity. Wheat germ agglutinin-AF488 is applied in fluorescence microscopy and confocal imaging techniques, and it can clearly label the membrane structures of various cells including breast cancer cells, enabling high-resolution visual observation. Wheat germ agglutinin-AF488 is used in studies of breast cancer and triple-negative breast cancer to observe cell morphology and membrane dynamic changes .
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Cat. No.: HY-D1991
CAS No.: 906664-68-4
ATTO 647 is a carborhodamine fluorophore and imaging tracer with photostable properties. ATTO 647 serves as a fluorescent probe to investigate cell membrane structure and diffusion characteristics. When conjugated with wheat germ agglutinin, ATTO 647 specifically binds to N-acetyl-β-D-glucosamine and sialic acid residues on membrane glycoproteins, enabling single-molecule tracing of glycoprotein diffusion. ATTO 647 exhibits highly stable fluorescence properties with significantly reduced blinking in mounting media such as ROXS (AA/MV) and ROXS (TX/TQ), whereas its brightness properties vary in Ibidi-MM and Vectashield. ATTO 647 can also be used to label histone H2B-GFP in fixed cells for confocal microscopy photobleaching experiments .
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Cat. No.: HY-150724B
Purity:  98.71%
Research Areas:  

Inflammation/Immunology

FITC-labeled ODN 1018 (sodium),an oligodeoxynucleotide, is a TLR-9 agonist. FITC-labeled ODN 1018 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
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Cat. No.: HY-150743B
Purity:  98.89%
Research Areas:  

Inflammation/Immunology

FITC-labeled ODN 2395 (sodium), a C class oligodeoxynucleotide, is a TLR9 agonist. FITC-labeled ODN 2395 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
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Cat. No.: HY-76779
CAS No.: 25392-41-0
Target:  

Drug Derivative

Research Areas:  

Cancer

4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .
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Cat. No.: HY-150741B
Purity:  97.34%
FITC-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. FITC-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
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Cat. No.: HY-150175
CAS No.: 1786411-17-3
Target:  

Fluorescent Dye

Research Areas:  

Inflammation/Immunology

HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O2 •−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O2 •−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O2 •− roles in inflammation, mitochondrial stress, and other physiological processes .
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Cat. No.: HY-D2994
CAS No.: 2434651-49-5
Synonyms: SNAP-MaP555
SPY555-BG (SNAP-MaP555) is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .
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Cat. No.: HY-D2341
CAS No.: 3055969-34-8
6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .
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