Wheat germ agglutinin-AF488
Based on 1 Customer Validation
Wheat germ agglutinin-AF488 (WGA-AF488) is a cell membrane-specific staining agent prepared by conjugating wheat germ agglutinin with the Alexa Fluor 488 (HY-D1304) fluorescent dye, and it binds to cell surface glycoproteins with high affinity. Wheat germ agglutinin-AF488 is applied in fluorescence microscopy and confocal imaging techniques, and it can clearly label the membrane structures of various cells including breast cancer cells, enabling high-resolution visual observation. Wheat germ agglutinin-AF488 is used in studies of breast cancer and triple-negative breast cancer to observe cell morphology and membrane dynamic changes.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Wheat germ agglutinin-AF488 (1 μg/mL; 5 min) effectively stains the surface of HEK293 cells, allowing clear visualization of cell boundaries in fluorescence microscopy[1].
Wheat germ agglutinin-AF488 (5 μg/mL; 5 min at 37 °C) labels the membranes of human breast cancer cell lines HCC-1954, MDA-MB-231, and SKBR3 for visualization via confocal fluorescence microscopy[2].
Wheat germ agglutinin-AF488 (5 μg/mL; 5 min at 37 °C) labels the membranes of human breast cancer cell line HCC-1954 for visualization and cell boundary identification via confocal fluorescence microscopy[2].
Wheat germ agglutinin-AF488 (5 μg/mL) stains the cell membrane of MDA-MB-468 cells, enabling membrane visualization in confocal fluorescence imaging[3].
Wheat germ agglutinin-AF488 (5 μg/mL) stains the cell membrane of MDA-MB-468 cells, enabling visualization of membrane structure during time-dependent cellular uptake studies of targeted DNA origami[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Color Yellow to orange
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SMILES
[Wheat germ agglutinin-AF488]
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Synonyms
WGA-AF488
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. FitzGerald LI, et al. A molecular sensor to quantify the localization of proteins, DNA and nanoparticles in cells. Nat Commun. 2020;11(1):4482. Published 2020 Sep 8. [Content Brief]
[2]. Boide-Trujillo VJ, et al. Functionalization of lipid nanoemulsions with humanized antibodies using plug-and-play cholesterol anchor for targeting cancer cells. Nanoscale Adv. 2025;7(22):7226-7238. Published 2025 Sep 23. [Content Brief]
[3]. Pal S, et al. Folate-Functionalized DNA Origami for Targeted Delivery of Doxorubicin to Triple-Negative Breast Cancer. Front Chem. 2021;9:721105. Published 2021 Aug 16. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Wheat germ agglutinin-AF488 Related Classifications
HY-NP163A Related Classifications
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