Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
diaminopyrimidine
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "diaminopyrimidine" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P2336A
Target:
Research Areas:
1
1 Cited Publications
Category:
Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer
Target:
1
1 Cited Publications
Research Areas:
KRCA-0008 is a selective ALK/Ack1 inhibitor with IC50s of 12 and 4 nM for ALK and Ack1, respectively. KRCA-0008 can be used for the research of cancer .
Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:
Research Areas:
Target:
Research Areas:
Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT . Metoprine is an antifolate and antitumor agent .
Cat. No.: HY-P5362
Research Areas:
Target:
Research Areas:
Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively .
Cat. No.: HY-P10341
CAS No.: 1345835-12-2
Target:
Research Areas:
Cat. No.: HY-18030A
CAS No.: 2070009-30-0
Target:
Research Areas:
CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally active ALK inhibitor with an IC50 value of 1.9 nM. CEP-28122 mesylate salt has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity. CEP-28122 mesylate salt can be used for the study of ALK-positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroblastoma cells .
Cat. No.: HY-18030
CAS No.: 1022958-60-6
Target:
Research Areas:
CEP-28122, a diaminopyrimidine derivative, is a potent, selective, and orally active ALK inhibitor with an IC50 value of 1.9 nM. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 has good pharmacodynamic and pharmacokinetic activity. CEP-28122 can be used for the study of ALK-positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroblastoma cells .
Cat. No.: HY-19506
CAS No.: 663214-64-0
Target:
Research Areas:
AR-709 is a diaminopyrimidine antibiotic. AR-709 exhibits potent antibacterial activity against Streptococcus pneumoniae (MIC = 0.03 mg/L). AR-709 can be used for research on bacterial infections .
Cat. No.: HY-P11004
Target:
Research Areas:
Cat. No.: HY-P10472
CAS No.: 134457-28-6
Target:
Research Areas:
Cat. No.: HY-P4757
CAS No.: 108081-77-2
Cat. No.: HY-P11243
Target:
Research Areas:
Cat. No.: HY-P2434
CAS No.: 846569-60-6
Target:
Research Areas:
Cat. No.: HY-W751832
Synonyms: 5,6-Diaminouracil hydrochloride-13C3
Cat. No.: HY-P5362A
Research Areas:
Cat. No.: HY-105168
CAS No.: 157380-72-8
Target:
Research Areas:
Cat. No.: HY-129441R
CAS No.: 7761-45-7
Synonyms: BW 197U (Standard)
Research Areas:
Metoprine (Standard) is the analytical standard of Metoprine. This product is intended for research and analytical applications. Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT . Metoprine is an antifolate and antitumor agent .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
