1. Autophagy
  2. Autophagy
  3. Aumitin

Aumitin 

Cat. No.: HY-124726
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Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively.

For research use only. We do not sell to patients.

Aumitin Chemical Structure

Aumitin Chemical Structure

CAS No. : 946293-78-3

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Description

Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1].

Molecular Weight

429.90

Formula

C₂₄H₂₀ClN₅O

CAS No.

946293-78-3

SMILES

O=C(NC1=CC=C(NC2=NC(NC3=CC=CC=C3)=CC(C)=N2)C=C1)C4=CC=CC=C4Cl

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Aumitin
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