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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
fluorescent probe substrate
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "fluorescent probe substrate" in MCE Product Catalog:
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2 Cited Publications
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7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H2S). In the presence of H2S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H2S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .
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2 Cited Publications
Cat. No.: HY-D1341
CAS No.: 878019-47-7
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Coumberone is a metabolic fluorogenic probe, and isoform-selective substrate for all AKR1C isoforms. Coumberone can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone can be used for the research of AKR1C .
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1 Cited Publications
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FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation .
Synonyms: BODIPY FL,SE
Cat. No.: HY-150145A
Purity: 99.26%
Cat. No.: HY-D1078
CAS No.: 127770-45-0
Cat. No.: HY-160250
CAS No.: 2097024-37-6
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UGT1A1-IN-1 is a UGT1A1 inhibitor and fluorescent probe (Ex=370 nm, Em=520 nm), with an IC50 of 1.33 μM and a Ki of 5.02 μM. UGT1A1-IN-1 is selectively glucuronidated by UGT1A1 at the bilirubin homologous binding site, and its PET effect is blocked along with this reaction, triggering fluorescence changes. UGT1A1-IN-1 can serve as a substitute for bilirubin to detect UGT1A1 activity and perform high-throughput screening of UGT1A1 modulators .
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Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase .
Cat. No.: HY-150145
Cat. No.: HY-D1685
CAS No.: 254451-46-2
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BZiPAR is a fluorescent probe. BZiPAR also is a substrate of trypsin that becomes fluorescent after cleavage by the protease .
Cat. No.: HY-D1021
CAS No.: 936327-10-5
Synonyms: Aminoallyl-dUTP sodium
Cat. No.: HY-110334
CAS No.: 1883548-88-6
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FFN 206 dihydrochloride, a fluorescent probe, is used as an excellent Vesicular Monoamine Transporter 2 (VMAT2) substrate with an apparent Km of 1.16 μM. FFN 206 dihydrochloride is capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles .
Cat. No.: HY-D1460
CAS No.: 134869-04-8
Cat. No.: HY-P3791
CAS No.: 133525-12-9
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Cat. No.: HY-W800701
CAS No.: 2762752-63-4
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Kynuramine is an endogenous amine that serves as a fluorescent substrate and probe for plasma amine oxidase .
Cat. No.: HY-D1609
CAS No.: 216571-88-9
Cat. No.: HY-W354821
CAS No.: 66185-70-4
Synonyms: 4-MUD
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
