FFN246
Based on 1 publication(s) in Google Scholar
FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation.
For research use only. We do not sell to patients.
- Purity: 99.59%
- CAS No.: 2210244-83-8
- Formula: C15H13FN2O
- Molecular Weight:256.27
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) FFN246
MoreAll 5-HT Receptor Isoforms
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Biological Activity
FFN246 (20 μM, 30 mins) effectively traces serotonin uptake and packaging in the soma of serotonergic neurons[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2210244-83-8
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Appearance Solid
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Molecular Weight 256.27
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Formula C15H13FN2O
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Color Light yellow to yellow
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SMILES
O=C1C2=CC(CCN)=CC=C2NC3=C1C(F)=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Rep
2026 Jun 23;45(6):117387. PMID: 42250222
Solvent & Solubility
DMSO : 16.67 mg/mL (65.05 mM; ultrasonic and warming and adjust pH to 1 with 1 M HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9021 mL | 19.5107 mL | 39.0213 mL | 97.5534 mL |
| 5 mM | 0.7804 mL | 3.9021 mL | 7.8043 mL | 19.5107 mL | |
| 10 mM | 0.3902 mL | 1.9511 mL | 3.9021 mL | 9.7553 mL | |
| 15 mM | 0.2601 mL | 1.3007 mL | 2.6014 mL | 6.5036 mL | |
| 20 mM | 0.1951 mL | 0.9755 mL | 1.9511 mL | 4.8777 mL | |
| 25 mM | 0.1561 mL | 0.7804 mL | 1.5609 mL | 3.9021 mL | |
| 30 mM | 0.1301 mL | 0.6504 mL | 1.3007 mL | 3.2518 mL | |
| 40 mM | 0.0976 mL | 0.4878 mL | 0.9755 mL | 2.4388 mL | |
| 50 mM | 0.0780 mL | 0.3902 mL | 0.7804 mL | 1.9511 mL | |
| 60 mM | 0.0650 mL | 0.3252 mL | 0.6504 mL | 1.6259 mL |
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