Fluorescein Di-β-D-Glucuronide
Based on 1 Customer Validation
Fluorescein Di-β-D-Glucuronide is an orally active fluorescent probe substrate and an indicator of β-glucuronidase (βG) activity in intestinal bacteria. Fluorescein Di-β-D-Glucuronide can be used for non-invasive time-lapse optical imaging of βG activity in intestinal bacteria in nude mice. Fluorescein Di-β-D-Glucuronide supports the quantitative analysis of bacterial βG enzyme activity and inhibition.
For research use only. We do not sell to patients.
- Purity: 96.58%
- CAS No.: 134869-04-8
- Formula: C32H28O17
- Molecular Weight:684.55
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Balb/c nude (7-week-old)[1]
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Dosage:7.3 μmol/kg
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Administration:p.o.; single dose
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Result:Detected a significant abdominal fluorescent signal, reaching a maximum total flux of 9.4 × 109 photons/second at 3 hours post-gavage, which was 13.3-fold higher than that in fluorescein-treated mice.
Showed a fluorescent signal in the large intestines that was 9.4-fold stronger than that in fluorescein-treated mice.
Detected slight, non-significant signals in the liver, stomach, kidney, and small intestines, which were at least 50-fold weaker than the large intestine signal.
Reduced the abdominal fluorescent signal.
Reduced the fluorescent signal in excised large intestine.
Chemical Information
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CAS No. 134869-04-8
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Appearance Solid
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Molecular Weight 684.55
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Formula C32H28O17
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Color Light yellow to yellow
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SMILES
O=C1OC2(C3=CC=C(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)C=C3OC5=CC(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=CC=C52)C7=CC=CC=C71
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (146.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4608 mL | 7.3041 mL | 14.6081 mL | 36.5203 mL |
| 5 mM | 0.2922 mL | 1.4608 mL | 2.9216 mL | 7.3041 mL | |
| 10 mM | 0.1461 mL | 0.7304 mL | 1.4608 mL | 3.6520 mL | |
| 15 mM | 0.0974 mL | 0.4869 mL | 0.9739 mL | 2.4347 mL | |
| 20 mM | 0.0730 mL | 0.3652 mL | 0.7304 mL | 1.8260 mL | |
| 25 mM | 0.0584 mL | 0.2922 mL | 0.5843 mL | 1.4608 mL | |
| 30 mM | 0.0487 mL | 0.2435 mL | 0.4869 mL | 1.2173 mL | |
| 40 mM | 0.0365 mL | 0.1826 mL | 0.3652 mL | 0.9130 mL | |
| 50 mM | 0.0292 mL | 0.1461 mL | 0.2922 mL | 0.7304 mL | |
| 60 mM | 0.0243 mL | 0.1217 mL | 0.2435 mL | 0.6087 mL | |
| 80 mM | 0.0183 mL | 0.0913 mL | 0.1826 mL | 0.4565 mL | |
| 100 mM | 0.0146 mL | 0.0730 mL | 0.1461 mL | 0.3652 mL |
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