29 Results for "

glutaric

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "glutaric" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-W014125
CAS No.: 1852-04-6
Undecanedioic acid is an oral activie nndogenous metabolite. Undecanedioic acid is associated with intercellular matrix macromolecules and specifically with elastin .
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1
1 Cited Publications
Cat. No.: HY-W008820S
CAS No.: 154184-99-3
Glutaric acid-d6 is the deuterium labeled Glutaric acid. Glutaric acid is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I .
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Cat. No.: HY-113038B
CAS No.: 2889-31-8
Purity:  ≥98.0%
Synonyms: 2-Hydroxyglutarate; 2-Hydroxyglutaric acid; 2-Hydroxypentanedioic acid
α-Hydroxyglutaric acid (2-Hydroxyglutarate) is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
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Cat. No.: HY-W008820
CAS No.: 110-94-1
Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I .
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Cat. No.: HY-113005
CAS No.: 102636-82-8
Purity:  95.03%
Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
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Cat. No.: HY-113038A
CAS No.: 40951-21-1
Purity:  ≥98.0%
Synonyms: 2-Hydroxyglutarate disodium; 2-Hydroxyglutaric acid disodium; 2-Hydroxypentanedioic acid disodium
α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
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Cat. No.: HY-113038AS
CAS No.: 2482467-23-0
Purity:  99.80%
Synonyms: 2-Hydroxyglutarate-13C5 disodium; 2-Hydroxyglutaric acid-13C5 disodium; 2-Hydroxypentanedioic acid-13C5 disodium
α-Hydroxyglutaric acid- 13C5 (sodium) is the 13C labeled α-Hydroxyglutaric acid sodium . α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
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Cat. No.: HY-159681
Target:  

Others

Research Areas:  

Metabolic Disease

AASS-IN-1 is a 2-aminoadipic semialdehyde synthase (AASS) inhibitor with a human IC50 of 142 µM. AASS-IN-1 inhibits AASS activity by binding to the LOR domain of AASS. AASS-IN-1 can be used for the research of glutaric aciduria type 1 .
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Cat. No.: HY-W073501
CAS No.: 628-48-8
Synonyms: trans-2-Pentenedioic acid
trans-Glutaconic acid (trans-2-Pentenedioic acid) is the trans isomer of Glutaconic acid (HY-W073501A). trans-Glutaconic acid is a neurotoxic metabolite. trans-Glutaconic acid induces weak neurotoxicity in cultured cerebral neocortical neurons. trans-Glutaconic acid elicits significant electrophysiological responses in rat neocortical wedge preparations at high concentrations. trans-Glutaconic acid can be used in studies related to glutaric acidemia type 1 .
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Cat. No.: HY-CE02028
CAS No.: 167357-83-7
Synonyms: Glutaconyl-coenzyme A
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Glutaconyl-CoA (Glutaconyl-coenzyme A) is a key metabolic intermediate in the mitochondrial catabolic pathways of lysine, hydroxylysine and tryptophan. Glutaconyl-CoA competitively inhibits wild-type glutaryl-CoA dehydrogenase (GCDH) with a Ki value of 1.1 µM. Glutaconyl-CoA is generated via the oxidative decarboxylation of glutaryl-CoA catalyzed by GCDH, and is subsequently further metabolized. Glutaconyl-CoA can be used in the research of type I glutaric aciduria .
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Cat. No.: HY-113411S
CAS No.: 1219805-72-7
Purity:  99.42%
3-Hydroxyglutaric acid-d5 is the deuterium labeled 3-Hydroxyglutaric acid. 3-Hydroxyglutaric acid is a glutaric acid derivative .
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Cat. No.: HY-113038AS1
CAS No.: 2483831-91-8
Purity:  95.9%
Synonyms: 2-Hydroxyglutarate-d4 disodium; 2-Hydroxyglutaric acid-d4 disodium; 2-Hydroxypentanedioic acid-d4 disodium
α-Hydroxyglutaric acid-d4 (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium . α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
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Cat. No.: HY-W008820R
CAS No.: 110-94-1
Glutaric acid (Standard) is the analytical standard of Glutaric acid. This product is intended for research and analytical applications. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I . In Vitro: Glutaric acid (GA) at concentrations of 1 and 2 mM is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM .
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Cat. No.: HY-113005A
Purity:  ≥99.0%
Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes .
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Cat. No.: HY-139070A
CAS No.: 109175-64-6
Purity:  ≥99.0%
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

D-Glyceric acid sodium is the sodium form of D-Glyceric acid (HY-139070A). D-Glyceric acid is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2 .
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Cat. No.: HY-W008820S1
CAS No.: 19136-99-3
Glutaric acid-d4 is the deuterium labeled Glutaric acid. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I .
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Cat. No.: HY-139070
CAS No.: 6000-40-4
D-Glyceric acid is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2 .
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Cat. No.: HY-138653
CAS No.: 195833-46-6
Synonyms: DGGR; 1,2-o-Dilauryl-rac-glycero-3-glutaric acid (6′-methylresorufin) ester
Target:  

Lipase

Research Areas:  

Metabolic Disease

Lipase Substrate is a chromogenic substrate of lipase to detect activity . It is used in colorimetric methods to measure lipase activity. It produces a red-purple compound, methylresorufin, upon digestion by the lipase enzyme.
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Cat. No.: HY-113005S
Purity:  ≥95.0%
Glutarylcarnitine-d9 (chloride) is the deuterium labeled Glutarylcarnitine chloride. Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
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