2889-31-8

α-Hydroxyglutaric acid Chemical Structure
2889-31-8

Chemical Structure

α-Hydroxyglutaric acid

Synonym(s): 2-Hydroxyglutarate; 2-Hydroxyglutaric acid; 2-Hydroxypentanedioic acid

  • CAS No.: 2889-31-8
  • Formula:C5H8O5
  • Molecular Weight:148.11

IUPAC Name: 2-hydroxypentanedioic acid

InChIKey: HWXBTNAVRSUOJR-UHFFFAOYSA-N

SMILES: O=C(O)C(O)CCC(O)=O

Biological Activity: α-Hydroxyglutaric acid (2-Hydroxyglutarate) is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[1].
The product specifications provided below refer solely to the active content of α-Hydroxyglutaric acid.

Cat. No. Product Name Purity Description Pricing
HY-113038B 		α-Hydroxyglutaric acid 99.56% α-Hydroxyglutaric acid (2-Hydroxyglutarate) is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases.
The product specifications provided below refer solely to the active content of α-Hydroxyglutaric acid.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

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