Glutarylcarnitine
Based on 1 Customer Validation
Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 102636-82-8
- Formula: C12H21NO6
- Molecular Weight:275.30
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Malonylcarnitine and Glutarylcarnitine are important diagnostic metabolites in the screening of dried blood spots by tandem mass spectrometry[1].
The urinary excretion of glutarylcarnitine is a specific biochemical marker of glutaric acidemia type I (GA-1). The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 102636-82-8
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Appearance Solid-Liquid Mixture
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Molecular Weight 275.30
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Formula C12H21NO6
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Color Colorless to light yellow
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SMILES
C[N+](C)(C)C[C@H](OC(CCCC(O)=O)=O)CC([O-])=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (363.24 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Johnson DW, et al. Stability of malonylcarnitine and Glutarylcarnitine in stored blood spots. J Inherit Metab Dis. 2004;27(6):789-90. [Content Brief]
[2]. S Tortorelli, et al. The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I. Mol Genet Metab. 2005 Feb;84(2):137-43. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 3.6324 mL | 18.1620 mL | 36.3240 mL | 90.8100 mL |
| 5 mM | 0.7265 mL | 3.6324 mL | 7.2648 mL | 18.1620 mL | |
| 10 mM | 0.3632 mL | 1.8162 mL | 3.6324 mL | 9.0810 mL | |
| 15 mM | 0.2422 mL | 1.2108 mL | 2.4216 mL | 6.0540 mL | |
| 20 mM | 0.1816 mL | 0.9081 mL | 1.8162 mL | 4.5405 mL | |
| 25 mM | 0.1453 mL | 0.7265 mL | 1.4530 mL | 3.6324 mL | |
| 30 mM | 0.1211 mL | 0.6054 mL | 1.2108 mL | 3.0270 mL | |
| 40 mM | 0.0908 mL | 0.4541 mL | 0.9081 mL | 2.2703 mL | |
| 50 mM | 0.0726 mL | 0.3632 mL | 0.7265 mL | 1.8162 mL | |
| 60 mM | 0.0605 mL | 0.3027 mL | 0.6054 mL | 1.5135 mL | |
| 80 mM | 0.0454 mL | 0.2270 mL | 0.4541 mL | 1.1351 mL | |
| 100 mM | 0.0363 mL | 0.1816 mL | 0.3632 mL | 0.9081 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Glutarylcarnitine Related Classifications
HY-113005 Related Classifications
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