Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
hCE2
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "hCE2" in MCE Product Catalog:
2
Category:
Leguminosae/Fabaceae Extract Plant Monophenols Psoralea corylifolia L. Extract Phenols Disease Research Fields Cancer
Target:
1
1 Cited Publications
Art. -Nr.: HY-P76192A
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES2; Carboxylesterase 2 (Intestine, Liver); Carboxylesterase 2; Cocaine Esterase; CE-2; Intestinal Carboxylesterase; Liver Carboxylesterase-2; ICE; Carboxylic Ester Hydrolase; CES2A1; PCE-2; Methylumbelliferyl-Acetate Deacetylase 2; hCE-2
Species:
Human
Source:
HEK293
Art. -Nr.: HY-N1377
CAS. Nr.: 10176-66-6
Synonyms: Lysionotin
Art. -Nr.: HY-N3474
CAS. Nr.: 94805-83-1
Category:
Flavonols Plant Flavonoids Other Diseases Phenols Polyphenols Other Families Extract Disease Research Fields
Target:
Art. -Nr.: HY-N0855
CAS. Nr.: 155521-46-3
Synonyms: Alisol-G; 25-Anhydroalisol A
Category:
Alisma plantago-aquatica Linn. Extract Triterpenes Plant Terpenoids Other Diseases Disease Research Fields Alismataceae Extract
Target:
Art. -Nr.: HY-N3413
CAS. Nr.: 254886-77-6
Art. -Nr.: HY-N0235R
CAS. Nr.: 10309-37-2
Synonyms: (S)-(+)-Bakuchiol (Standard)
Art. -Nr.: HY-N3921
CAS. Nr.: 126716-36-7
Category:
Leguminosae/Fabaceae Extract Plant Flavonoids Glycyrrhiza uralensis Fisch. Extract Disease Research Fields Cancer Isoflavones
Target:
Art. -Nr.: HY-N1377R
CAS. Nr.: 10176-66-6
Synonyms: Lysionotin (Standard)
Art. -Nr.: HY-155228
Target:
Forschungsgebiete:
hCES2A-IN-2 (Compound 44) is an orally active human carboxylesterase 2 (hCES2A) inhibitor (IC50: 5.02 μM). hCES2A-IN-2 improves Irinotecan (HY-16562)-induced delayed diarrhea .
Art. -Nr.: HY-147915
CAS. Nr.: 2416220-53-4
Forschungsgebiete:
Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids .
Art. -Nr.: HY-176465
CAS. Nr.: 3037959-47-7
Target:
Forschungsgebiete:
CES2A-IN-3 (Compound 9d) is a potent serine-targeting covalent human carboxylesterase 2A (hCES2A) inhibitor with an IC50 value of 0.12 nM. CES2A-IN-3 is promising for research of diarrhea and ulcerative colitis .
Art. -Nr.: HY-P76193
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CES2; Carboxylesterase 2 (Intestine, Liver); Carboxylesterase 2; Cocaine Esterase; CE-2; Intestinal Carboxylesterase; Liver Carboxylesterase-2; ICE; Carboxylic Ester Hydrolase; CES2A1; PCE-2; Methylumbelliferyl-Acetate Deacetylase 2; hCE-2
Species:
Mouse
Source:
HEK293
Art. -Nr.: HY-P76192
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES2; Carboxylesterase 2 (Intestine, Liver); Carboxylesterase 2; Cocaine Esterase; CE-2; Intestinal Carboxylesterase; Liver Carboxylesterase-2; ICE; Carboxylic Ester Hydrolase; CES2A1; PCE-2; Methylumbelliferyl-Acetate Deacetylase 2; hCE-2
Species:
Human
Source:
HEK293
Art. -Nr.: HY-190794
Target:
Carboxylesterase (CES) Reactive Oxygen Species (ROS) Interleukin Related Mitochondrial Metabolism
Forschungsgebiete:
CES2A-IN-4 is an orally active, time-dependent, irreversible, and selective CES2A inhibitor (hCES2A: IC50 value of 6.87 nM after 3 min preincubation, and IC50 value of 0.052 nM after 33 min preincubation). CES2A-IN-4 attenuates Irinotecan (HY-16562)-induced inflammation by reducing IL-6 and ROS levels and maintaining mitochondrial membrane potential .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
