Kushenol X
Based on 1 Customer Validation
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 254886-77-6
- Formula: C25H28O7
- Molecular Weight:440.49
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
IC50: 2.07 μM (β-glucuronidase)[1] and 3.05 μM (Human carboxylesterase 2 (hCE2))[2]
Chemical Information
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CAS No. 254886-77-6
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Appearance Solid
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Molecular Weight 440.49
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Formula C25H28O7
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Color White to off-white
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SMILES
CC([C@H](C/C=C(C)/C)CC(C(O)=C1)=C(O[C@H](C(C=CC(O)=C2)=C2O)[C@H]3O)C(C3=O)=C1O)=C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Cheng-Peng Sun, et al. The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase. Int J Biol Macromol. 2020 Jan 15;143:349-358. [Content Brief]
[2]. Sha-Sha Song, et al. Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations. Int J Biol Macromol. 2019 Jun 15;131:201-208. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)