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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
240 Results for "
helix
" in MedChemExpress (MCE) Product Catalog:
Products (240)
240 Results for "helix" in MCE Product Catalog:
9
9 Publications Verification
Cat. No.: HY-P80704
Synonyms: HIF1A; BHLHE78; MOP1; PASD8; Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS doma
9
9 Publications Verification
Target:
Research Areas:
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8 μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis
9
9 Publications Verification
Target:
Research Areas:
BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC) . BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM .
7
5
4
4 Cited Publications
Cat. No.: HY-P74888
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HIF1A; Basic-helix-Loop-helix-PAS Protein MOP1; Hypoxia Inducible Factor 1 Subunit Alpha; HIF-1-Alpha; BHLHe78; Hypoxia Inducible Factor 1 Alpha Subunit; PASD8; Hypoxia-Inducible Factor1alpha; MOP1; Member Of PAS Superfamily 1; Class E Basic helix-Loop-helix Protein 78; ARNT Interacting Protein; Hypoxia-Inducible Factor 1-Alpha; ARNT-Interacting Protein; PAS Domain-Containing Protein 8; HIF1-ALPHA; Member Of PAS Protein 1; HIF1-Alpha; HIF-1alpha; BHLHE78; HIF1; HIF-1A; Hypoxia Inducible Factor 1, Alpha Subunit (Basic helix-Loop-helix Transcription Factor)
Species:
Human
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P80900
Synonyms: SREBF1; BHLHD1; SREBP1; Sterol regulatory element-binding protein 1; SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1
3
Research Areas:
9-Amino-6-chloro-2-methoxyacridine (ACMA) is an acridine derivative and Fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine inhibits viral replication, inhibits DNA synthesis and protein metabolism through cell cycle arrest, and induces lipid metabolism regulation, genotoxicity, mutagenicity, and cytotoxicity through DNA strand breaks. 9-Amino-6-chloro-2-methoxyacridine partially intercalates into DNA, forming three distinct complexes, stabilizes the DNA helix, and quenches fluorescence upon intercalation through electron transfer with guanine. 9-Amino-6-chloro-2-methoxyacridine monitors the generation and collapse of the proton motive force, H + pumping by F1F0-ATP synthase, and the collapse of pH gradients in inverted membrane vesicles. 9-Amino-6-chloro-2-methoxyacridine shows potent anti-BVDV activity. 9-Amino-6-chloro-2-methoxyacridine can be used for research on bovine viral diarrhea virus infection, leishmaniasis, and MRSA infection .
2
2 Cited Publications
Cat. No.: HY-P700468
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GLP1R; GLP-1-R; Glucagon Like Peptide 1 Receptor; Seven Transmembrane helix Receptor; Glucagon-Like Peptide 1 Receptor; GLP1 Receptor; GLP-1R; GLP-1; GLP-1 Receptor
Species:
Human
Source:
HEK293
1
Target:
Research Areas:
Beta-glucuronidase (helix pomatia) is a glycosyl hydrolase that hydrolyzes β-glucuronic acid and sulfate esters in urine and other biological fluids, and then releases β-glucuronate .
1
1 Cited Publications
Cat. No.: HY-P701228
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TFEB; Class E Basic helix-Loop-helix Protein 35; Transcription Factor EB; T-Cell Transcription Factor EB; BHLHe35; ALPHATFEB; TCFEB; BHLHE35
Species:
Human
Source:
E. coli
1
1
1
1 Cited Publications
Cat. No.: HY-P704066
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MYC; V-Myc Myelocytomatosis Viral Oncogene Homolog; MYC Proto-Oncogene, BHLH Transcription Factor; Class E Basic helix-Loop-helix Protein 39; BHLHe39; MRTL; Myc Proto-Oncogene Protein; V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian), Isoform CRA_b;
Species:
Human
Source:
E. coli
1
1
1 Cited Publications
Cat. No.: HY-P80155
Synonyms: bHLHb39 antibody;
C-HAIRY1 antibody;
Class B basic helix-loop-helix protein 39 antibody;
FLJ20408 antibody;
Hairy and enhancer of split 1 antibody;
Hairy homolog (Drosophila) antibody;
Hairy homolog antibody;
Hairy like antibody;
Hairy, Drosophila, homolog of antibody;
Hairy-like protein antibody;
HAIRY1 antibody;
HES-1 antibody;
HES1_HUMAN antibody;
HHL antibody;
HL antibody;
HRY antibody;
MGC129109 antibody;
OTTHUMP00000209031 antibody;
RHL antibody;
Transcription factor HES-1 antibody
1
1 Cited Publications
Cat. No.: HY-P72206
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GLP1R; GLP-1-R; Glucagon Like Peptide 1 Receptor; Seven Transmembrane helix Receptor; Glucagon-Like Peptide 1 Receptor; GLP1 Receptor; GLP-1R; GLP-1; GLP-1 Receptor
Species:
Mouse
Source:
E. coli
Target:
Research Areas:
Sulfatase, Helix pomatia is an enzyme that catalyzes the hydrolysis of sulfate esters. Sulfatase, Helix pomatia participates in the metabolism of various substances .
Cat. No.: HY-P5960
Synonyms: PTBP1 α3-helix derived peptide P6 TFA
Target:
Research Areas:
Cat. No.: HY-N0254
CAS No.: 760961-03-3
Category:
Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae Extract
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
