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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
199 Results for "
helix
" in MedChemExpress (MCE) Product Catalog:
Products (199)
199 Results for "helix" in MCE Product Catalog:
9
9 Publications Verification
Target:
Research Areas:
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8 μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis
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9 Publications Verification
Cat. No.: HY-P80704
Synonyms: HIF1A; BHLHE78; MOP1; PASD8; Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS doma
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9 Publications Verification
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BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC) . BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM .
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2
2 Cited Publications
Cat. No.: HY-P80900
Synonyms: SREBF1; BHLHD1; SREBP1; Sterol regulatory element-binding protein 1; SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1
1
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Beta-glucuronidase (helix pomatia) is a glycosyl hydrolase that hydrolyzes β-glucuronic acid and sulfate esters in urine and other biological fluids, and then releases β-glucuronate .
1
1 Cited Publications
Cat. No.: HY-N0306
CAS No.: 36284-77-2
Category:
Infection Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Terpenoids Plants Disease Research Fields Araliaceae
Target:
1
1
1
1 Cited Publications
Cat. No.: HY-P72229
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HNRNPA 1; helix destabilizing protein; helix-destabilizing protein; Heterogeneous nuclear ribonucleoprotein A1; Heterogeneous nuclear ribonucleoprotein A1B protein; Heterogeneous nuclear ribonucleoprotein B2 protein; Heterogeneous nuclear ribonucleoprotein core protein A1; hnRNP A1; hnRNP core protein A1; HNRNPA1; HNRPA1;
1
1 Cited Publications
Cat. No.: HY-P704066
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AU016757; Avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; Cellular myelocytomatosis oncogene; Class E basic helix-loop-helix protein 39; MGC105490; MRTL; Myc; Myc protein; Myc proto oncogene protein; Myc proto-oncogene protein; myc-related translation/localization regulatory factor; MYC_HUMAN; Myc2; myca; MYCC
1
1 Cited Publications
Cat. No.: HY-P80155
Synonyms: bHLHb39 antibody;
C-HAIRY1 antibody;
Class B basic helix-loop-helix protein 39 antibody;
FLJ20408 antibody;
Hairy and enhancer of split 1 antibody;
Hairy homolog (Drosophila) antibody;
Hairy homolog antibody;
Hairy like antibody;
Hairy, Drosophila, homolog of antibody;
Hairy-like protein antibody;
HAIRY1 antibody;
HES-1 antibody;
HES1_HUMAN antibody;
HHL antibody;
HL antibody;
HRY antibody;
MGC129109 antibody;
OTTHUMP00000209031 antibody;
RHL antibody;
Transcription factor HES-1 antibody
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Research Areas:
Sulfatase, Helix pomatia is an enzyme that catalyzes the hydrolysis of sulfate esters. Sulfatase, Helix pomatia participates in the metabolism of various substances .
Cat. No.: HY-P0311
CAS No.: 184776-51-0
Cat. No.: HY-P5960
Synonyms: PTBP1 α3-helix derived peptide P6 TFA
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Research Areas:
PS210 is a potent and selective PDK1 activator with a Kd of 3 μM and targets the PIF-binding pocket of PDK1. PS210 is inactive against other protein kinases, including PDK1 downstream signaling components such as S6K, PKB/Akt or GSK3. In cells, the prodrug of PS210 (PS423) acts as a substrate-selective inhibitor of PDK1, inhibiting the phosphorylation and activation of S6K .
Cat. No.: HY-N0254
CAS No.: 760961-03-3
Category:
Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae
Target:
Cat. No.: HY-P10904
CAS No.: 51486-77-2
Synonyms: ST-100
Cat. No.: HY-P0311A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
