2. Cytoskeleton
  3. Collagen
  4. Vezocolmitide

Vezocolmitide (ST-100) is a collagen mimetic peptide. Vezocolmitide can rapidly repair damaged collagen triple helix structures, thereby quickly reversing damage to the ocular surface and extracellular matrix, and restoring corneal nerve function while repairing the epithelium. Vezocolmitide can be used for research of dry eye disease (DED).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Vezocolmitide

Vezocolmitide Chemical Structure

CAS No. : 51486-77-2

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Vezocolmitide Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Vezocolmitide (ST-100) is a collagen mimetic peptide. Vezocolmitide can rapidly repair damaged collagen triple helix structures, thereby quickly reversing damage to the ocular surface and extracellular matrix, and restoring corneal nerve function while repairing the epithelium. Vezocolmitide can be used for research of dry eye disease (DED)[1].

In Vitro

Vezocolmitide improves tear production, alleviates ocular surface damage, and relieves discomfort in dry eye disease, with a favorable safety and tolerability profile[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Vezocolmitide Related Antibodies
Clinical Trial
Molecular Weight

1776.99

Formula

C84H121N21O22
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Pro-Pro-Gly-Pro-Pro-Gly-Pro-Pro-Gly-Pro-Pro-Gly-Pro-Pro-Gly-Pro-Pro-Gly-Pro-Pro-Gly
Sequence Shortening

PPGPPGPPGPPGPPGPPGPPG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (56.27 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5627 mL 2.8137 mL 5.6275 mL
5 mM 0.1125 mL 0.5627 mL 1.1255 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.5627 mL 2.8137 mL 5.6275 mL 14.0687 mL
5 mM 0.1125 mL 0.5627 mL 1.1255 mL 2.8137 mL
10 mM 0.0563 mL 0.2814 mL 0.5627 mL 1.4069 mL
15 mM 0.0375 mL 0.1876 mL 0.3752 mL 0.9379 mL
20 mM 0.0281 mL 0.1407 mL 0.2814 mL 0.7034 mL
25 mM 0.0225 mL 0.1125 mL 0.2251 mL 0.5627 mL
30 mM 0.0188 mL 0.0938 mL 0.1876 mL 0.4690 mL
40 mM 0.0141 mL 0.0703 mL 0.1407 mL 0.3517 mL
50 mM 0.0113 mL 0.0563 mL 0.1125 mL 0.2814 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Vezocolmitide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vezocolmitide51486-77-2ST-100ST100ST 100CollagencollagenpeptideDEDInhibitorinhibitorinhibit

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