11 Results for "

hepatic cell integrity

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "hepatic cell integrity" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-B0859
CAS No.: 94-74-6
MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds .
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1 Cited Publications
Cat. No.: HY-N0853A
CAS No.: 18674-16-3
Synonyms: Alisol A 24-monoacetate; Alisol A monoacetate
Alisol A 24-acetate (Alisol A monoacetate) is an orally active derivative of protostane-type tetracyclic triterpenoid. Alisol A 24-acetate upregulates the expression of adiponectin, AMPKα, CPT1, and ACOX1; downregulates the expression of SREBP-1c, ACC, FAS, Bcl-2, Bcl-xl, PPAR-γ, perilipin A, and NFATc1; inhibits the activity of PI3K/Akt/mTOR and HMGR; and activates the PKA and ERK signaling pathways. Alisol A 24-acetate regulates cell apoptosis (apoptosis), autophagy (Autophagy, hepatic lipid accumulation, inflammatory response, neuroprotection, MRSA membrane integrity, and osteoclast differentiation. Alisol A 24-acetate can be used in research related to non-alcoholic fatty liver disease, nephrotoxicity, obesity, global cerebral ischemia-reperfusion injury, bacterial infection, and osteoporosis .
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1 Cited Publications
Cat. No.: HY-B0859A
CAS No.: 3653-48-3
Research Areas:  

Metabolic Disease

MCPA sodium is an orally active phenoxyacetic acid herbicide. MCPA sodium interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA sodium increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA sodium can be used to control broadleaf weeds .
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Cat. No.: HY-W019704
CAS No.: 1115-47-5
N-Acetyl-DL-methionine is an orally active methionine analog and a glutathione (GSH) precursor that can be metabolized into cysteine in vivo. N-Acetyl-DL-methionine increases plasma methionine concentration and the molar percentage of plasma lysine in castrated sheep, and can partially meet the methionine requirement of growing rats. N-Acetyl-DL-methionine is absorbable from the lower digestive tract of sheep and undergoes ruminal microbial degradation in vivo. N-Acetyl-DL-methionine alleviates Acetaminophen (HY-66005)-induced hepatic GSH depletion in mice, maintains hepatocyte integrity, and promotes de novo synthesis of hepatic GSH. N-Acetyl-DL-methionine can be used in studies related to acetaminophen-induced liver injury .
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Cat. No.: HY-B0859S1
CAS No.: 352431-14-2
MCPA-d3 is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds .
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Cat. No.: HY-136855
CAS No.: 652968-37-1
Purity:  95.00%
MitoPBN is a AMPK/SIRT3/PGC-1α axis modulator, reactive oxygen species scavenger and mitochondrial function enhancer. MitoPBN increases the phosphorylation level of AMPK, restores SIRT3 expression and reverses the down-regulation of PGC-1α, thereby promoting mitochondrial biogenesis. MitoPBN regulates glucose metabolism, reduces blood glucose by inhibiting hepatic gluconeogenesis and increasing hepatic glucose uptake, while scavenging mitochondrial superoxide anion/hydrogen peroxide, maintaining membrane potential and increasing ATP production. MitoPBN also reduces cell apoptosis, improves sperm motility, survival rate and membrane integrity, but may induce reductive stress in cryopreserved sperm at high concentrations. MitoPBN is widely applicable to research related to diabetes and type 2 diabetes .
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Cat. No.: HY-W713900
CAS No.: 2469242-78-0
MCPA-d3-1 is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds .
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Cat. No.: HY-B0859R
CAS No.: 94-74-6
MCPA (Standard) is the analytical standard of MCPA (HY-B0859). This product is intended for research and analytical applications. MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds .
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Cat. No.: HY-B0859S
Synonyms: 4-Chloro-2-Methylphenoxyacetic acid-13C8
MCPA- 13C8 is the 13C-labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds .
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Cat. No.: HY-105885
CAS No.: 69217-67-0
Synonyms: SUR 2647
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Sumacetamol (SUR 2647) is the N-acetyl-DL-methionine ester of Paracetamol (HY-66005). Sumacetamol is orally active. Sumacetamol enhances the hepatic GSH synthesizing capacity in Bom:NMRI mice after experimental overdosage and offers protection of hepatic cell integrity, when combined with Paracetamol .
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Cat. No.: HY-N20719
CAS No.: 3162-56-9
Vulgarin is an orally active, naturally occurring eudesmane sesquiterpene with multiple biological activities including anti-inflammatory and antioxidant properties. Vulgarin targets and inhibits HMGB1, NF-κB and iNOS, while regulating key genes involved in hepatic gluconeogenesis; it also blocks inflammatory signaling pathways and inhibits the production and release of pro-inflammatory cytokines such as TNF-α and IL-1β. Vulgarin effectively alleviates pancreatic oxidative stress by reducing lipid peroxidation levels and restoring antioxidant enzyme activity. Vulgarin reverses abnormally elevated serum pancreatic enzyme levels, preserves the integrity of pancreatic acinar cells, and reduces pancreatic edema, hemorrhage and inflammatory infiltration. Vulgarin remodels the function of pancreatic endocrine cells, restores insulin content in β cells, and downregulates glucagon levels in α cells and somatostatin levels in δ cells. Vulgarin can be used in studies related to pancreatic injury and diabetes .
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