1115-47-5
Chemical Structure
N-Acetyl-DL-methionine
- CAS No.: 1115-47-5
- Formula:C7H13NO3S
- Molecular Weight:191.25
IUPAC Name: acetylmethionine
InChIKey: XUYPXLNMDZIRQH-UHFFFAOYSA-N
SMILES: OC(C(CCSC)NC(C)=O)=O
Biological Activity: N-Acetyl-DL-methionine is an orally active methionine analog and a glutathione (GSH) precursor that can be metabolized into cysteine in vivo. N-Acetyl-DL-methionine increases plasma methionine concentration and the molar percentage of plasma lysine in castrated sheep, and can partially meet the methionine requirement of growing rats. N-Acetyl-DL-methionine is absorbable from the lower digestive tract of sheep and undergoes ruminal microbial degradation in vivo. N-Acetyl-DL-methionine alleviates Acetaminophen (HY-66005)-induced hepatic GSH depletion in mice, maintains hepatocyte integrity, and promotes de novo synthesis of hepatic GSH. N-Acetyl-DL-methionine can be used in studies related to acetaminophen-induced liver injury[1][2].
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N-Acetyl-DL-methionine | 98.40% | N-Acetyl-DL-methionine is an orally active methionine analog and a glutathione (GSH) precursor that can be metabolized into cysteine in vivo. N-Acetyl-DL-methionine increases plasma methionine concentration and the molar percentage of plasma lysine in castrated sheep, and can partially meet the methionine requirement of growing rats. N-Acetyl-DL-methionine is absorbable from the lower digestive tract of sheep and undergoes ruminal microbial degradation in vivo. N-Acetyl-DL-methionine alleviates Acetaminophen (HY-66005)-induced hepatic GSH depletion in mice, maintains hepatocyte integrity, and promotes de novo synthesis of hepatic GSH. N-Acetyl-DL-methionine can be used in studies related to acetaminophen-induced liver injury. | ||||||||||||||||||||
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N-Acetyl-DL-methionine (Standard) | ≥98% | N-Acetyl-DL-methionine (Standard) is the analytical standard of N-Acetyl-DL-methionine (HY-W019704). This product is intended for research and analytical applications. N-Acetyl-DL-methionine is an orally active methionine analog and a glutathione (GSH) precursor that can be metabolized into cysteine in vivo. N-Acetyl-DL-methionine increases plasma methionine concentration and the molar percentage of plasma lysine in castrated sheep, and can partially meet the methionine requirement of growing rats. N-Acetyl-DL-methionine is absorbable from the lower digestive tract of sheep and undergoes ruminal microbial degradation in vivo. N-Acetyl-DL-methionine alleviates Acetaminophen (HY-66005)-induced hepatic GSH depletion in mice, maintains hepatocyte integrity, and promotes de novo synthesis of hepatic GSH. N-Acetyl-DL-methionine can be used in studies related to acetaminophen-induced liver injury. | ||||||||||||||||||||
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Similarity Score 1.00
HY-W012497N-Acetyl-D-methionine -
Similarity Score 1.00
HY-W012499RN-Acetyl-L-methionine (Standard) -
Similarity Score 0.84
HY-113080N-Acetylornithine -
Similarity Score 0.83
HY-W016647RFor-Met-OH (Standard) -
Similarity Score 0.81
HY-W048838Acetyl-L-lysine -
Similarity Score 0.81
HY-W015240RN-Acetyl-L-glutamic acid (Standard) -
Similarity Score 0.81
HY-W015241Ac-D-Glu-OH -
Similarity Score 0.81
HY-183648N-Acetyl-S-(3-hydroxy-1-methylpropyl)-L-cysteine -
Similarity Score 0.81
HY-114976S-Allylmercapturic acid -
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References
- [1]. Amos HE, et al. Methionine, DL-Homocysteine Thiolactone and N-Acetyl-DL-Methionine for Ruminants. Journal of Animal Science. 1974;39(3):612-617.
- [2]. Skoglund LA, et al. Efficacy of paracetamol-esterified methionine versus cysteine or methionine on paracetamol-induced hepatic GSH depletion and plasma ALAT level in mice. Biochemical pharmacology. 1986 Sep 15;35(18):3071-5. [Content Brief]
