2. Metabolic Enzyme/Protease
  3. Herbicide Cytochrome P450
  4. MCPA sodium

MCPA sodium is an orally active phenoxyacetic acid herbicide. MCPA sodium interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA sodium increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA sodium can be used to control broadleaf weeds.

For research use only. We do not sell to patients.

MCPA sodium

MCPA sodium Chemical Structure

CAS No. : 3653-48-3

Size Price Stock Quantity
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of MCPA sodium:

MCPA sodium Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE MCPA sodium

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A CYP3A4 CYP17A1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MCPA sodium is an orally active phenoxyacetic acid herbicide. MCPA sodium interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA sodium increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA sodium can be used to control broadleaf weeds[1][2][3][4][5].

In Vitro

MCPA (50 μM) sodium is taken up by Caco-2 cells mainly via monocarboxylic acid transporters shared with benzoic acid and partially via L-lactic acid[1].
MCPA (20-120 μM; 4 weeks) sodium inhibits growth of non-green potato tuber calli, disrupts membrane integrity, reduces energy charge, and affects redox state and antioxidant enzyme activities[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MCPA sodium Related Antibodies
In Vivo

MCPA (200 mg/kg/day; p.o.; 2 weeks) sodium increases hepatic cytochrome P-450 level and activities of aniline hydroxylase and 7-ethoxycoumarin O-deethylase in male rats[4].
MCPA (14C-MCPA; 5-100 mg/kg; p.o.; single or multiple doses) sodium is rapidly absorbed and excreted mainly in urine in rats, with limited metabolism to HMCPA and glycine conjugate[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

222.60

Formula

C9H8ClNaO3
CAS No.
Appearance

Solid

SMILES

O=C(COC1=CC=C(C=C1C)Cl)O[Na]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (449.24 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4924 mL 22.4618 mL 44.9236 mL
5 mM 0.8985 mL 4.4924 mL 8.9847 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.4924 mL 22.4618 mL 44.9236 mL 112.3091 mL
5 mM 0.8985 mL 4.4924 mL 8.9847 mL 22.4618 mL
10 mM 0.4492 mL 2.2462 mL 4.4924 mL 11.2309 mL
15 mM 0.2995 mL 1.4975 mL 2.9949 mL 7.4873 mL
20 mM 0.2246 mL 1.1231 mL 2.2462 mL 5.6155 mL
25 mM 0.1797 mL 0.8985 mL 1.7969 mL 4.4924 mL
30 mM 0.1497 mL 0.7487 mL 1.4975 mL 3.7436 mL
40 mM 0.1123 mL 0.5615 mL 1.1231 mL 2.8077 mL
50 mM 0.0898 mL 0.4492 mL 0.8985 mL 2.2462 mL
60 mM 0.0749 mL 0.3744 mL 0.7487 mL 1.8718 mL
80 mM 0.0562 mL 0.2808 mL 0.5615 mL 1.4039 mL
100 mM 0.0449 mL 0.2246 mL 0.4492 mL 1.1231 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

MCPA sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MCPA3653-48-3HerbicideCytochrome P450CYPsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
MCPA sodium
Cat. No.:
HY-B0859A
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.