MCPA sodium
Based on 1 publication(s) in Google Scholar
MCPA sodium is an orally active phenoxyacetic acid herbicide. MCPA sodium interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA sodium increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA sodium can be used to control broadleaf weeds.
For research use only. We do not sell to patients.
- CAS No.: 3653-48-3
- Formula: C9H8ClNaO3
- Molecular Weight:222.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) MCPA sodium
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Biological Activity
MCPA (50 μM) sodium is taken up by Caco-2 cells mainly via monocarboxylic acid transporters shared with benzoic acid and partially via L-lactic acid[1].
MCPA (20-120 μM; 4 weeks) sodium inhibits growth of non-green potato tuber calli, disrupts membrane integrity, reduces energy charge, and affects redox state and antioxidant enzyme activities[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MCPA (14C-MCPA; 5-100 mg/kg; p.o.; single or multiple doses) sodium is rapidly absorbed and excreted mainly in urine in rats, with limited metabolism to HMCPA and glycine conjugate[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3653-48-3
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Appearance Solid
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Molecular Weight 222.60
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Formula C9H8ClNaO3
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SMILES
O=C(COC1=CC=C(C=C1C)Cl)O[Na]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Solvent & Solubility
H2O : 100 mg/mL (449.24 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Kimura O, et al. Uptake of 4-chloro-2-methylphenoxyacetic acid (MCPA) from the apical membrane of Caco-2 cells by the monocarboxylic acid transporter. Toxicol Appl Pharmacol. 2008 Mar 15;227(3):325-30. [Content Brief]
[4]. Inomata N, et al. Effects of MCPA and other phenoxyacid compounds on hepatic xenobiotic metabolism in rats. Tohoku J Exp Med. 1991 Nov;165(3):171-82. [Content Brief]
[5]. van Ravenzwaay B, et al. Absorption, distribution, metabolism and excretion of 4-chloro-2-methylphenoxyacetic acid (MCPA) in rats. Food Chem Toxicol. 2004 Jan;42(1):115-25. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.4924 mL | 22.4618 mL | 44.9236 mL | 112.3091 mL |
| 5 mM | 0.8985 mL | 4.4924 mL | 8.9847 mL | 22.4618 mL | |
| 10 mM | 0.4492 mL | 2.2462 mL | 4.4924 mL | 11.2309 mL | |
| 15 mM | 0.2995 mL | 1.4975 mL | 2.9949 mL | 7.4873 mL | |
| 20 mM | 0.2246 mL | 1.1231 mL | 2.2462 mL | 5.6155 mL | |
| 25 mM | 0.1797 mL | 0.8985 mL | 1.7969 mL | 4.4924 mL | |
| 30 mM | 0.1497 mL | 0.7487 mL | 1.4975 mL | 3.7436 mL | |
| 40 mM | 0.1123 mL | 0.5615 mL | 1.1231 mL | 2.8077 mL | |
| 50 mM | 0.0898 mL | 0.4492 mL | 0.8985 mL | 2.2462 mL | |
| 60 mM | 0.0749 mL | 0.3744 mL | 0.7487 mL | 1.8718 mL | |
| 80 mM | 0.0562 mL | 0.2808 mL | 0.5615 mL | 1.4039 mL | |
| 100 mM | 0.0449 mL | 0.2246 mL | 0.4492 mL | 1.1231 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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