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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
human fragment D
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "human fragment D" in MCE Product Catalog:
3
Target:
Research Areas:
1
1
Synonyms: GLP-1-Gly8; GLP-1 (7-36) analog
Target:
Research Areas:
Cat. No.: HY-P4767
CAS No.: 198328-30-2
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Cat. No.: HY-P3602
CAS No.: 99027-06-2
Cat. No.: HY-P4817
CAS No.: 157938-23-3
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Cat. No.: HY-108795A
Purity: 99.12%
Synonyms: GLP-1-Gly8 TFA; GLP-1 (7-36) analog TFA
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Research Areas:
Cat. No.: HY-108795R
CAS No.: 224638-84-0
Synonyms: GLP-1-Gly8 (Standard); GLP-1 (7-36) analog (Standard)
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Cat. No.: HY-P70862
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: METAP1D; Peptidase M 1D; Methionyl Aminopeptidase Type 1D, Mitochondrial; MetAP 1D; MAP1D; MAP 1D; Metap1l; CDS Of MetAP-3 Within PCR fragment; Methionine Aminopeptidase 1D, Mitochondrial; Methionine Aminopeptidase 1D
Species:
Human
Source:
E. coli
Cat. No.: HY-P705528
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: METAP1D; Peptidase M 1D; Methionyl Aminopeptidase Type 1D, Mitochondrial; MetAP 1D; MAP1D; MAP 1D; Metap1l; CDS Of MetAP-3 Within PCR fragment; Methionine Aminopeptidase 1D, Mitochondrial; Methionine Aminopeptidase 1D
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-181168
Target:
Research Areas:
Lb54 is a caspase-3 and caspase-7 activator with an EC50 of 660.9 nM for human procaspase-3. Lb54 activates caspase-3/7, which cleaves Gasdermin D (GSDMD) at aspartic acid residue 87 to generate a p10 fragment, preventing formation of the pore-forming p30 fragment of GSDMD. Lb54 suppresses GSDMD-mediated pyroptosis through caspase-3/7 activation, thereby attenuating inflammatory responses and conferring protection against sepsis. Lb54 alleviates acute lung injury, and inhibited systemic inflammation by restraining the maturation of monocyte-derived dendritic cells. Lb54 can be used for the research of sepsis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
