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hydrolysing

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin-converting Enzyme (ACE) (5) Apoptosis (2) Bacterial (2) Biochemical Assay Reagents (17) COX (1) Dipeptidyl Peptidase (1) Drug Intermediate (2) Drug Metabolite (1) Endogenous Metabolite (10) Fluorescent Dye (4) Glycosidase (2) Isotope-Labeled Compounds (2) Parasite (2) Phosphatase (1) Proteasome (1) Reactive Oxygen Species (ROS) (2) Reference Standards (4)
By Research Areas:	Cardiovascular Disease (8) Inflammation/Immunology (2) Metabolic Disease (14) Neurological Disease (3)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1787

Dimethyl malonate 5+ Cited Publications	Apoptosis	Neurological Disease
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-123053

Z-Leu-Leu-Glu-AMC 3 Publications Verification Z-LLE-AMC	Proteasome	Neurological Disease
Z-Leu-Leu-Glu-AMC (Z-LLE-AMC) is a peptide-AMC linked substrate used to measure the postacidic-like hydrolysing activity of proteasome. Z-Leu-Leu-Glu-AMC can be used for the research of parkinson's disease .

HY-B0592

Trandolapril RU44570	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-15927

4-Nitrophenyl β-D-glucopyranoside 1 Publications Verification	Biochemical Assay Reagents	Metabolic Disease
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .

HY-B0757A

(±)-α-Tocopherol nicotinate rel-Vitamin E Nicotinate	Reactive Oxygen Species (ROS) Endogenous Metabolite	Cardiovascular Disease
(±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases .

HY-131131

5-CFDA-AM	Fluorescent Dye	Others
5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein, which contains an additional negative charge and can be better retained in the cell. 5-CFDA-AM can be used to detect cell viability .

HY-P3261

Inulinase	Biochemical Assay Reagents	Others
Inulinase is expressed in various microorganisms, including yeasts, fungi, mesophilic bacteria. Inulinase can be used to produce inulooligosaccharides from inulin and inulin-containing materials. Inulinase produced by yeast has hydrolysing capability towards sucrose, inulin, levan type fructans exo-wise .

HY-E70397A

Dipeptidyl Peptidase IV, Porcine Kidney DPP-IV, Porcine Kidney	Dipeptidyl Peptidase	Metabolic Disease
Dipeptidyl Peptidase IV, Porcine Kidney (DPP-IV, Porcine Kidney) is a serine aminopeptidase with multiple physiological roles. Dipeptidyl Peptidase IV, Porcine Kidney hydrolyses gastric inhibitory peptide (GIP) and glucagon-like peptide 1 (GLP-1), the most important insulin-releasing hormones (incretins) of the enteroinsular axis .

HY-W209628

Methyl 2-acetoxybenzoate Methyl acetylsalicylate	Drug Intermediate	Inflammation/Immunology
Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) is a safe and simple anti-inflammatory aspirin prodrug. Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) can be chemical or enzymatically hydrolysed to methyl 2-hydroxy benzoate. Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) can be used as analgesic agent in liniments and also inflammatory diseases research .

HY-N2093

Vicine 2 Publications Verification	Drug Metabolite	Cardiovascular Disease Metabolic Disease
Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food .

HY-D1699

PFB-FDG	Fluorescent Dye	Others
PFB-FDG is a non-fluorescent galactosidase substrate that can be hydrolysed to green fluorescent PFB-F (Ex=485 nm, Em=535 nm). PFB-FDG can be used for the determination of β-galactosidase activity .

HY-121657

Ornidazole diol Ro 11-2616	Parasite Bacterial	Others
Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.

HY-Y1787R

Dimethyl malonate (Standard)	Reference Standards Apoptosis	Neurological Disease
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-137103

BTC-AM	Fluorescent Dye	Others
BTC-AM is a low affinity calcium indicator. BTC-AM has substantial calcium-independent fluorescence at all excitation wavelengths. BTC-AM is readily loaded into neurons and is rapidly hydrolysed .

HY-P4427

Z-VAN-AMC	Fluorescent Dye	Others
Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity .

HY-124178

(R)-Levrazoxane (R)-ICRF 186	Drug Intermediate	Metabolic Disease
(R)-Levrazoxane ((R)-ICRF 186) is enzymatically hydrolysed to one-ring open intermediates by dihydropyrimidine amidohydrolase (DPHase), which is present in the liver and kidney. The radiosensitizing efficiency of (R)-Levrazoxane towards EMT6 mouse mammary tumour cells is greater than that of Dexrazoxane (HY-B0581). (R)-Levrazoxane is promising for research of liver and kidney related diseases .

HY-121657R

Ornidazole diol (Standard) Ro 11-2616 (Standard)	Parasite Bacterial Reference Standards	Others
Ornidazole diol (Standard) is an analytical standard for Ornidazole diol. This product is used for research and analytical applications. Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.

HY-121322

Neoagarobiose	Others	Others
Neoagarobiose has both a moisturizing effect on skin and a whitening effect on melanoma cells. RagaA11 is an endo-type beta-agarase hydrolysing not only agarose, but also neoagarotetraose, to yield neoagarobiose as the final main product .

HY-B0592A

Trandolapril hydrochloride RU44570 hydrochloride	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Trandolapril (RU44570) hydrochloride is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolapril hydrochlorideat. Trandolapril hydrochloride is an orally active angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-19675

Naproxen etemesil LT-NS 001; MX 1094	COX	Inflammation/Immunology
Naproxen etemesil is a lipophilic, non-acidic, inactive proagent of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC₅₀s of 8.72 and 5.15 μM, respectively in cell assay.

HY-B0592R

Trandolapril (Standard) RU44570 (Standard)	Reference Standards Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Trandolapril (Standard) is the analytical standard of Trandolapril. This product is intended for research and analytical applications. Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-W744298

Trandolapril-d3	Isotope-Labeled Compounds Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Trandolapril-d₃ is the deuterium labeled Trandolapril (HY-B0592). Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-B0592S2

rac-Trandolapril-d5 rac-RU44570-d₅	Isotope-Labeled Compounds Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
rac-Trandolapril-d₅ (rac-RU44570-d₅) is deuterium labeled Trandolapril. Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-B0757AR

(±)-α-Tocopherol nicotinate (Standard) rel-Vitamin E Nicotinate (Standard)	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite	Cardiovascular Disease
(±)-α-Tocopherol nicotinate (Standard) is the analytical standard of (±)-α-Tocopherol nicotinate. This product is intended for research and analytical applications. (±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases[1][2].

HY-E71307

β-L-Rhamnosidase	Glycosidase	Others
β-L-Rhamnosidase (EC 3.2.1.43) belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O-and S-glycosyl compounds.

HY-E71276

β-Aspartyl-N-acetylglucosaminidase	Biochemical Assay Reagents	Others
β-Aspartyl-N-acetylglucosaminidase (EC 3.2.2.11) belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds.

HY-E70914

Phosphatase, Escherichia coli	Phosphatase	Metabolic Disease
Phosphatase, Escherichia coli (EC 3.1.3.-) is an enzyme that removes a phosphate group from its substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group.

HY-E71169

1,6-α-L-Fucosidase	Glycosidase	Others
1,6-α-L-Fucosidase (EC 3.2.1.127) belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds.

HY-E71286

β-D-Fucosidase	Biochemical Assay Reagents	Others
β-D-Fucosidase (EC 3.2.1.38) hydrolyse β-D-galactosides and/or β-D-glucosides and/or α-L-arabinosides.

HY-P2871I

α-Galactosidase, Green coffee beans	Biochemical Assay Reagents	Metabolic Disease
α-Galactosidase, Green coffee beans (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins.

HY-B2193H

α-Amylase, Porcine	Endogenous Metabolite	Metabolic Disease
α-Amylase, Porcine (EC 3.2.1.1) is a protein enzyme that hydrolyses alpha bonds of large, alpha-linked polysaccharides, such as starch and glycogen, yielding glucose and maltose.

HY-B2193E

α-Amylase, Bacteroides fragilis	Endogenous Metabolite	Metabolic Disease
α-Amylase, Bacteroides fragilis (EC 3.2.1.1) is a protein enzyme that hydrolyses alpha bonds of large, alpha-linked polysaccharides, such as starch and glycogen, yielding glucose and maltose.

HY-E71204

α,α-Phosphotrehalase	Biochemical Assay Reagents	Others
α,α-Phosphotrehalase (EC 3.2.1.93) belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O-and S-glycosyl compounds. This enzyme participates in starch and sucrose metabolism.

HY-B2193D

α-Amylase, Escherichia coli	Endogenous Metabolite	Metabolic Disease
α-Amylase, Escherichia coli (EC 3.2.1.1) is a protein enzyme that hydrolyses alpha bonds of large, alpha-linked polysaccharides, such as starch and glycogen, yielding glucose and maltose.

HY-E71324

β-Primeverosidase	Biochemical Assay Reagents	Others
β-Primeverosidase (EC 3.2.1.149) is responsible for the formation of the alcoholic aroma in oolong and black tea. In addition to β-primeverosides [i.e. 6-O-(β-D-xylopyranosyl)-β-D-glucopyranosides], it also hydrolyses 6-O-(β-D-apiofuranosyl)-β-D-glucopyranosides and, less rapidly, β-vicianosides and 6-O-(α-L-arabinofuranosyl)-β-D-glucopyranosides, but not β-glucosides. Geranyl-, linaloyl-, benzyl-and p-nitrophenol glycosides are all hydrolysed.

HY-P2871E

α-Galactosidase, Cellvibrio mixtus	Endogenous Metabolite	Metabolic Disease
α-Galactosidase, Cellvibrio mixtus (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. Two recombinant forms of α-Galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN).

HY-P2871D

α-Galactosidase, Clostridium cellulolyticum	Endogenous Metabolite	Metabolic Disease
α-Galactosidase, Clostridium cellulolyticum (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. Two recombinant forms of α-Galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN).

HY-P2871H

α-Galactosidase, Thermus brockianus	Endogenous Metabolite	Metabolic Disease
α-Galactosidase, Thermus brockianus (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. Two recombinant forms of α-Galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN).

HY-P2871C

α-Galactosidase, positionally specific, Escherichia coli	Endogenous Metabolite	Metabolic Disease
α-Galactosidase, positionally specific, Escherichia coli (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. Two recombinant forms of α-Galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN).

HY-E71229A

α-Galactosidase 110A, Bacteroides thetaiotaomicron	Biochemical Assay Reagents	Others
α-Galactosidase 110A, Bacteroides thetaiotaomicron (EC 3.2.1.-) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN) .

HY-E71229

α-Galactosidase 110A, Bacteroides fragilis	Biochemical Assay Reagents	Others
α-Galactosidase 110A, Bacteroides fragilis (EC 3.2.1.-) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN) .

HY-E71231

α-Galactosidase 4A, Bacillus halodurans	Biochemical Assay Reagents	Others
α-Galactosidase 4A, Bacillus halodurans (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN) .

HY-E71230

α-Galactosidase 27A, Clostridium cellulolyticum	Biochemical Assay Reagents	Others
α-Galactosidase 27A, Clostridium cellulolyticum (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN) .

HY-E71233

α-Galactosidase 97A, Bacteroides thetaiotaomicron	Biochemical Assay Reagents	Others
α-Galactosidase 97A, Bacteroides thetaiotaomicron (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN) .

HY-E71232

α-Galactosidase 95A, Bacteroides ovatus	Biochemical Assay Reagents	Others
α-Galactosidase 95A, Bacteroides ovatus (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN) .

HY-E71234

α-Galactosidase 97B, Bacteroides thetaiotaomicron	Biochemical Assay Reagents	Others
α-Galactosidase 97B, Bacteroides thetaiotaomicron (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN) .

HY-E71159

1,4-Lactonase	Biochemical Assay Reagents	Others
1,4-Lactonase (EC 3.1.1.25) is specific for 1,4-lactones with 4-8 carbon atoms. It does not hydrolyse simple aliphatic esters, acetylcholine, sugar lactones or substituted aliphatic lactones, e.g. 3-hydroxy-4-butyrolactone; requires Ca2+.

HY-E71288

β-D-Glucopyranosyl abscisate β-glucosidase	Biochemical Assay Reagents	Others
β-D-Glucopyranosyl abscisate β-glucosidase (EC 3.2.1.175) hydrolzes the biologically inactive β-D-Glucopyranosyl ester of abscisic acid to produce active abscisate. Abscisate is a phytohormone critical for plant growth, development and adaption to various stress conditions. The enzyme does not hydrolyse β-D-Glucopyranosyl zeatin.

HY-E71022

Trypsin Acetylated, Bovine	Endogenous Metabolite	Metabolic Disease
Trypsin Acetylated, Bovine (EC 3.4.21.4) is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyses proteins. Trypsin is produced in the pancreas as the inactive protease trypsinogen. Trypsin cleaves peptide chains mainly at the carboxyl side of the amino acids lysine or arginine, except when either is followed by proline.

HY-E71239A

α-Glucuronidase 4A, Thermotoga maritima	Biochemical Assay Reagents	Others
α-Glucuronidase 4A, Thermotoga maritima (EC 3.2.1.139) is an enzyme that catalyzes the chemical reaction: an alpha-D-glucuronoside + H2O ? an alcohol + D-glucuronate. Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate. α-Glucuronidase 4A, Thermotoga maritima (EC 3.2.1.139) belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O-and S-glycosyl compounds.

Cat. No.	Product Name	Type

HY-131131

5-CFDA-AM

Fluorescent Dye

5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein, which contains an additional negative charge and can be better retained in the cell. 5-CFDA-AM can be used to detect cell viability .

HY-D1699

PFB-FDG	Fluorescent Dye
PFB-FDG is a non-fluorescent galactosidase substrate that can be hydrolysed to green fluorescent PFB-F (Ex=485 nm, Em=535 nm). PFB-FDG can be used for the determination of β-galactosidase activity .

HY-137103

BTC-AM	Fluorescent Dye
BTC-AM is a low affinity calcium indicator. BTC-AM has substantial calcium-independent fluorescence at all excitation wavelengths. BTC-AM is readily loaded into neurons and is rapidly hydrolysed .

Cat. No.	Product Name	Type

HY-15927

4-Nitrophenyl β-D-glucopyranoside

1 Publications Verification

Biochemical Assay Reagents

4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .

HY-B0757A

(±)-α-Tocopherol nicotinate rel-Vitamin E Nicotinate	Biochemical Assay Reagents
(±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases .

HY-E70180

α-Galactosidase A EC:3.2.1.22; GLA	Biochemical Assay Reagents
alpha-Galactosidase A is a lysosomal exoglycosidase and hydrolyses the terminal α-galactosyl moieties of glycoconjugates .

HY-B0757AR

(±)-α-Tocopherol nicotinate (Standard)

rel-Vitamin E Nicotinate (Standard)

Biochemical Assay Reagents

(±)-α-Tocopherol nicotinate (Standard) is the analytical standard of (±)-α-Tocopherol nicotinate. This product is intended for research and analytical applications. (±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases[1][2].

Cat. No.	Product Name	Target	Research Area

HY-123053

Z-Leu-Leu-Glu-AMC 3 Publications Verification Z-LLE-AMC	Proteasome	Neurological Disease
Z-Leu-Leu-Glu-AMC (Z-LLE-AMC) is a peptide-AMC linked substrate used to measure the postacidic-like hydrolysing activity of proteasome. Z-Leu-Leu-Glu-AMC can be used for the research of parkinson's disease .

HY-P4427

Z-VAN-AMC	Fluorescent Dye	Others
Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y1787

Dimethyl malonate 5+ Cited Publications	Structural Classification Natural Products Melia azedarach L. Plants Meliaceae Source Classification	Apoptosis
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-B0757A

(±)-α-Tocopherol nicotinate rel-Vitamin E Nicotinate	Cardiovascular Disease Alkaloids Classification of Application Fields Pyridine Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Reactive Oxygen Species (ROS) Endogenous Metabolite
(±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases .

HY-N2093

Vicine 2 Publications Verification	Alkaloids Classification of Application Fields Leguminosae Other Alkaloids Metabolic Disease Plants Vicia faba L. Disease Research Fields Source Classification	Drug Metabolite
Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food .

HY-Y1787R

Dimethyl malonate (Standard)	Structural Classification Natural Products Melia azedarach L. Plants Meliaceae Source Classification	Reference Standards Apoptosis
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-121322

Neoagarobiose	Structural Classification Natural Products Microorganisms Source Classification	Others
Neoagarobiose has both a moisturizing effect on skin and a whitening effect on melanoma cells. RagaA11 is an endo-type beta-agarase hydrolysing not only agarose, but also neoagarotetraose, to yield neoagarobiose as the final main product .

HY-B0757AR

(±)-α-Tocopherol nicotinate (Standard) rel-Vitamin E Nicotinate (Standard)	Alkaloids Pyridine Alkaloids Endogenous metabolite Source Classification	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite
(±)-α-Tocopherol nicotinate (Standard) is the analytical standard of (±)-α-Tocopherol nicotinate. This product is intended for research and analytical applications. (±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases[1][2].

Cat. No.	Product Name	Chemical Structure

HY-W744298

Trandolapril-d3
Trandolapril-d₃ is the deuterium labeled Trandolapril (HY-B0592). Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

HY-B0592S2

rac-Trandolapril-d5

rac-Trandolapril-d₅ (rac-RU44570-d₅) is deuterium labeled Trandolapril. Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) .

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hydrolysing

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products