152-93-2
152-93-2
Chemical Structure
Vicine
- CAS No.: 152-93-2
- Formula:C10H16N4O7
- Molecular Weight:304.26
IUPAC Name: 2,6-diamino-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pyrimidin-4(1H)-one
InChIKey: KGNGTSCIQCLKEH-SYCVNHKBSA-N
SMILES: O=C1N=C(N)NC(N)=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O
Biological Activity: Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Vicine | 99.79% | Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food. | ||||||||||||||||||||
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Vicine (Standard) | ≥98% | Vicine (Standard) is the analytical standard of Vicine. This product is intended for research and analytical applications. Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals and may cause haemolytic anaemia. | ||||||||||||||||||||
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Convicine | 95.19% | Convicine is a pyrimidine glycoside. Convicine, as well as Vicine, is the precursor of the aglycones Divicine and Isouramil. Convicine is the main factors of favism, which is a genetic condition leading to severe hemolysis after faba bean ingestion. Convicine can be isolated from the faba bean. | ||||||||||||||||||||
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Orcinol glucoside (Standard) | ≥98% | Orcinol glucoside (Standard) is the analytical standard of Orcinol glucoside. This product is intended for research and analytical applications. Orcinol glucoside (OG) is an active constituent isolated from Curculigo orchioides, with antidepressant effects. Orcinol glucoside facilitates the shift of MSC fate to osteoblast and prevents adipogenesis via Wnt/β-catenin signaling pathway. | ||||||||||||||||||||
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Arbutin | 99.76% | Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties. | ||||||||||||||||||||
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Erigeroside | Erigeroside is as a derivatives of -glucose extracted from Satureja khuzistanica Jamzad. Erigeroside has good ability of anti-oxidation and scavenging oxidation free radical. | |||||||||||||||||||||
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α-Arbutin (Standard) | 99.65% | α-Arbutin (Standard) is the analytical standard of α-Arbutin. This product is intended for research and analytical applications. α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is emerging as popular and effective skin whiteners, acting as tyrosinase inhibitor. | ||||||||||||||||||||
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Phlorin | 98% | Phlorin (Phloroglucinol β-D-glucoside) is a phloroglucinol (PG) glucoside. | ||||||||||||||||||||
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4-Aminophenyl-β-D-galactopyranoside, 98% | 99.98% | 4-Aminophenyl-β-D-galactopyranoside, 98% is a highly efficient substrate for β-galactosidase. It is specifically hydrolyzed by this enzyme to release galactose and electroactive p-aminophenol. 4-Aminophenyl-β-D-galactopyranoside, 98% is widely used in colorimetric and electrochemical assays for detecting β-galactosidase activity and determining enzyme kinetics, such as in biosensing fields including cellular senescence, pathogen and contaminant detection. In addition, since β-galactosidase is often overexpressed in primary ovarian cancer, 4-Aminophenyl-β-D-galactopyranoside, 98% can also be applied to related research on primary ovarian cancer. | ||||||||||||||||||||
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4-Aminophenyl-α-D-mannopyranoside, 98% | 98.0% | 4-Aminophenyl-α-D-mannopyranoside, 98% is a mannopyranoside. 4-Aminophenyl-α-D-mannopyranoside, 98%, after conjugation to the surface of liposomes, can enhance delivery to the mouse brain via GLUT1- and GLUT3-mediated transport. 4-Aminophenyl-α-D-mannopyranoside, 98% can be detected as a characteristic glycoside in the metabolomics of fermented foods and is considered a potential health-related metabolic marker. 4-Aminophenyl-α-D-mannopyranoside, 98% can be used in studies of glycosylation processes and enzyme-substrate interactions. | ||||||||||||||||||||
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4-Aminophenyl β-D-glucopyranoside | 98.93% | 4-Aminophenyl β-D-glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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p-Aminophenyl α-D-glucopyranoside | p-Aminophenyl α-D-glucopyranoside can be used in glycobiology research. | |||||||||||||||||||||
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References
- [1]. Farran MT, et al. Vicine and convicine in common vetch (Vicia sativa) seeds enhance beta-cyanoalanine toxicity in male broiler chicks. Int J Toxicol. 2002 May-Jun;21(3):201-9. [Content Brief]
- [2]. Lattanzio V, et al. Variability of amino acids, protein, vicine and convicine in Vicia faba (L) cultivars[J]. Journal of Food Science, 1983, 48(3): 992-993.
- [3]. Liener IE. Toxic constituents of plant foodstuffs. Proc Nutr Soc. 1970 May;29(1):56-7. [Content Brief]
- [4]. Khazaei H, et al. Eliminating vicine and convicine, the main anti-nutritional factors restricting faba bean usage[J]. Trends in Food Science & Technology, 2019, 91: 549-556.
