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Results for "

hydroxycoumarin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	17β-HSD (1) ADC Payload (1) Apoptosis (4) ATF6 (1) Bacterial (7) Biochemical Assay Reagents (3) Cytochrome P450 (2) DNA Stain (1) DNA/RNA Synthesis (1) Drug Derivative (3) Drug Intermediate (3) Drug Metabolite (1) Endogenous Metabolite (2) Fluorescent Dye (6) Fungal (5) Isotope-Labeled Compounds (4) Lipoxygenase (2) NADPH Oxidase (1) Parasite (2) Phosphodiesterase (PDE) (1) Phospholipase (1) Reference Standards (6) Somatostatin Receptor (1) Thrombin (1) Tyrosinase (1)
By Research Areas:	Cancer (17) Cardiovascular Disease (2) Endocrinology (2) Infection (8) Inflammation/Immunology (11) Metabolic Disease (4) Neurological Disease (4)

By Targets:

17β-HSD (1)

ADC Payload (1)

Apoptosis (4)

ATF6 (1)

Bacterial (7)

Biochemical Assay Reagents (3)

Cytochrome P450 (2)

DNA Stain (1)

DNA/RNA Synthesis (1)

Drug Derivative (3)

Drug Intermediate (3)

Drug Metabolite (1)

Endogenous Metabolite (2)

Fluorescent Dye (6)

Fungal (5)

Isotope-Labeled Compounds (4)

Lipoxygenase (2)

NADPH Oxidase (1)

Parasite (2)

Phosphodiesterase (PDE) (1)

Phospholipase (1)

Reference Standards (6)

Somatostatin Receptor (1)

Thrombin (1)

Tyrosinase (1)

By Research Areas:

Cancer (17)

Cardiovascular Disease (2)

Endocrinology (2)

Infection (8)

Inflammation/Immunology (11)

Metabolic Disease (4)

Neurological Disease (4)

Inhibitors & Agonists

Fluorescent Dyes

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17365

Octreotide acetate 15+ Cited Publications SMS 201-995 acetate	Somatostatin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.

HY-N0573

Umbelliferone 5 Publications Verification 7-hydroxycoumarin; Hydrangin; NSC 19790	Apoptosis Fluorescent Dye	Neurological Disease Inflammation/Immunology Cancer
Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-125586

β-Amanitin	DNA/RNA Synthesis ADC Payload	Cancer
β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .

HY-N6856

4-Hydroxycoumarin	Bacterial Endogenous Metabolite	Infection Cancer
4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-127170

3-Hydroxycoumarin	Lipoxygenase Tyrosinase	Metabolic Disease Inflammation/Immunology
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase with an IC₅₀ for recombinant human tyrosinase (rHT) of 26 μM, and a K_i of 3.39 μM; its IC₅₀ for LOX is 9.5 μM. 3-Hydroxycoumarin has DPPH free radical scavenging activity (IC₅₀ = 31.2 μM). 3-Hydroxycoumarin has photoprotective effects on sea urchin zygotes and embryos .

HY-W540978

3-Azido-7-hydroxycoumarin	Biochemical Assay Reagents	Others
3-Azido-7-hydroxycoumarin is a click chemistry reagent containing an azido group. Under Cu (II) catalysis, it undergoes azide-alkyne cycloaddition (CuAAC) click reaction with 3-butyn-1-ol and emits a fluorescent signal .

HY-133091

7-Ethoxycoumarin 7-O-Ethylumbelliferone	Cytochrome P450	Metabolic Disease
7-Ethoxycoumarin is a substrate of cytochrome P450 (CYP450). 7-Ethoxycoumarin has been used for the functional characterization of various CYPs and for the generation of 7-hydroxycoumarin (HY-N0573) .

HY-N6656

6-Hydroxycoumarin	Fungal Bacterial	Inflammation/Immunology Cancer
6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity .

HY-76779

4-(Chloromethyl)-7-hydroxycoumarin	Drug Derivative	Cancer
4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .

HY-P10447

Plipastatin A1 Fengycin IX; SNA-60-367-3	Phospholipase Fungal	Infection
Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold ^[1][2].

HY-N0573R

Umbelliferone (Standard) 7-hydroxycoumarin (Standard); Hydrangin (Standard); NSC 19790 (Standard)	Reference Standards Apoptosis Fluorescent Dye	Neurological Disease Inflammation/Immunology Cancer
Umbelliferone (Standard) (7-Hydroxycoumarin (Standard)) is the analytical standard of Umbelliferone (HY-N0573). This product is intended for research and analytical applications. Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats.

HY-N0573S

Umbelliferone-d5 7-hydroxycoumarin-d₅; Hydrangin-d₅; NSC 19790-d₅	Isotope-Labeled Compounds Apoptosis Fluorescent Dye	Neurological Disease Inflammation/Immunology Cancer
Umbelliferone-d₅ (7-Hydroxycoumarin-d₅) is the deuterium labeled Umbelliferone (HY-N0573 ). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-N6856R

*4-Hydroxycoumarin* (Standard)**	Reference Standards Bacterial Endogenous Metabolite	Infection Cancer
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-W023023

3-Carboxy-6-hydroxycoumarin	Drug Intermediate	Others
3-Carboxy-6-hydroxycoumarin is an intermediate in organic syntheses .

HY-D0112

*7-Hydroxycoumarin-4-acetic acid*	Fluorescent Dye	Others
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λ_max=326 nm) .

HY-127170R

*3-Hydroxycoumarin* (Standard)**	Lipoxygenase Reference Standards	Others
3-Hydroxycoumarin (Standard) is the analytical standard of 3-Hydroxycoumarin. This product is intended for research and analytical applications. 3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage .

HY-152084

Anticancer agent 93	Drug Derivative	Cancer
Anticancer agent 93 is a 4-Hydroxycoumarin derivative. Anticancer agent 93 can inhibit invasion and migration of lung cancer cells by modulating expression of epithelial-mesenchymal transition (EMT) effectors .

HY-21509

8-Hydroxycoumarin 1 Publications Verification	NADPH Oxidase	Others
8-Hydroxycoumarin is an intermediate in the microbial transformation of quinolone .

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

HY-D0115

*7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester*	DNA Stain	Others
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids .

HY-D0114

3-Carboxy-7-Hydroxycoumarin	Fluorescent Dye	Others
3-Carboxy-7-Hydroxycoumarin is a UV-light excitable fluorescent dye .

HY-133091R

7-Ethoxycoumarin (Standard) 7-O-Ethylumbelliferone (Standard)	Cytochrome P450 Reference Standards	Metabolic Disease
7-Ethoxycoumarin (Standard) is the analytical standard of 7-Ethoxycoumarin. This product is intended for research and analytical applications. 7-Ethoxycoumarin is a substrate of cytochrome P450 (CYP450). 7-Ethoxycoumarin has been used for the functional characterization of various CYPs and for the generation of 7-hydroxycoumarin (HY-N0573) .

HY-158104

LPPM-8	ATF6	Others
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

HY-143935S

*7-Hydroxycoumarin* sulfate-d5**	Isotope-Labeled Compounds	Others
7-Hydroxycoumarin sulfate-d₅ is the deuterium labeled 7-Hydroxycoumarin sulfate .

HY-W267205

3-Acetyl-7-Hydroxycoumarin	17β-HSD	Endocrinology Cancer
3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis .

HY-138145

8-Acetyl-7-hydroxycoumarin	Fungal Bacterial	Infection
8-Acetyl-7-hydroxycoumarin is a coumarin-like compound found in Mexican patchouli (Tagetes lucida) that has anti-bacterial and anti-fungal activities .

HY-150662S

*2-(7-Hydroxycoumarin-4-yl)-propanoic acid methyl ester-d3*	Isotope-Labeled Compounds	Others
2-(7-Hydroxycoumarin-4-yl)-propanoic acid methyl ester-d₃ is the deuterium labeled 2-(7-Hydroxycoumarin-4-yl)-propanoic acid methyl ester .

HY-W777393

Umbelliferone-13C6 7-hydroxycoumarin-¹³C₆; Hydrangin-¹³C₆; NSC 19790-¹³C₆	Isotope-Labeled Compounds Apoptosis Fluorescent Dye	Neurological Disease Inflammation/Immunology Cancer
Umbelliferone- ¹³C₆ (7-Hydroxycoumarin- ¹³C₆) is the ¹³C-labeled Umbelliferone (HY-N0573). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-N3373R

Loganetin (Standard)	Reference Standards Bacterial	Infection
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-N7650

Dihydroseselin	Biochemical Assay Reagents	Others
Dihydroseselin is a derivative of 7-hydroxycoumarin (HY-N0573). 7-hydroxycoumarin, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent

HY-161364

Antibacterial agent 200	Bacterial	Inflammation/Immunology
Antibacterial agent 200 (pyridyl HH 7), a unique hydrazyl hydroxycoumarin (HH), has strong antibacterial efficacy and broad antibacterial spectrum with MIC values ranging from 0.5 to 32 μg/mL for Gram-positive and Gram-negative bacteria. Antibacterial agent 200 exhibits a good inhibition against Pseudomonas aeruginosa 27853 with a low MIC value of 0.5 μg/mL. Antibacterial agent 200 can eradicate the integrity of bacterial membrane, result in the leakage of intracellular proteins, and interact with bacterial DNA gyrase via non-covalent binding .

HY-152085

Anticancer agent 94	Drug Derivative	Cancer
Anticancer agent 94 is a 4-Hydroxycoumarin derivative. Anticancer agent 94 can inhibit invasion and migration of lung cancer cells by modulating expression of epithelial-mesenchymal transition (EMT) effectors .

HY-N9440

*7-Hydroxycoumarin* glucuronide**	Drug Metabolite	Inflammation/Immunology Cancer
7-Hydroxycoumarin glucuronide is a transport substrate and main human coumarin metabolite. ^[1]7-Hydroxycoumarin glucuronide undergoes ATP-dependent efflux transport via MRP3 and MRP4. ^[1]7-Hydroxycoumarin glucuronide undergoes active transport processes for urinary excretion and is primarily excreted into urine in humans.

HY-N6656R

*6-Hydroxycoumarin* (Standard)**	Fungal Reference Standards Bacterial	Inflammation/Immunology Cancer
6-Hydroxycoumarin (Standard) is the analytical standard of 6-Hydroxycoumarin (HY-N6656). This product is intended for research and analytical applications. 6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity .

HY-N18093

5-Hydroxycoumarin	Drug Intermediate	Inflammation/Immunology Cancer
5-Hydroxycoumarin is a monohydroxycoumarin compound that occurs in the stems of Alyxia lucida, a plant of the genus Alyxia (Apocynaceae) .

HY-21510

5-Methyl-8-hydroxycoumarin	Drug Intermediate	Others
5-Methyl-8-hydroxycoumarin is a drug intermediate for synthesis of various active compounds.

HY-N17623

Ainsliaeasin C	Thrombin	Cardiovascular Disease
Ainsliaeasin C, a 7-hydroxycoumarin derivative, is an orally active anticoagulant agent that can be found in Ainsliaea fragrans. Ainsliaeasin C exerts anticoagulant activity both in vitro and in vivo. Ainsliaeasin C can be used for the research on thrombotic disorders .

HY-P11783

Surfactin C2	Fungal	Infection
Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .

HY-P2209

Nummularine B Daechuine S27; N-Demethylamphibine H	Parasite Phosphodiesterase (PDE)	Infection
Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC₅₀ of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca ²⁺-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

*7-Hydroxycoumarin-4-acetic acid*	Fluorescent Dyes
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λ_max=326 nm) .

*7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester*	Fluorescent Dyes
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids .

3-Carboxy-7-Hydroxycoumarin	Fluorescent Dyes
3-Carboxy-7-Hydroxycoumarin is a UV-light excitable fluorescent dye .

Cat. No.	Product Name	Target	Research Area

HY-17365

Octreotide acetate 15+ Cited Publications SMS 201-995 acetate	Somatostatin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.

HY-125586

β-Amanitin	DNA/RNA Synthesis ADC Payload	Cancer
β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .

HY-105055

Didemnin B	Peptides	Cancer
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

HY-P10447

Plipastatin A1 Fengycin IX; SNA-60-367-3	Phospholipase Fungal	Infection
Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold ^[1][2].

HY-P4755

*N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide*	Peptides	Others
N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

HY-125357

Ternatin	Peptides	Metabolic Disease
Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC₅₀ of 0.027 μM in 3T3-L1 adipocytes .

HY-158104

LPPM-8	ATF6	Others
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

HY-P11783

Surfactin C2	Fungal	Infection
Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .

HY-P2209

Nummularine B Daechuine S27; N-Demethylamphibine H	Parasite Phosphodiesterase (PDE)	Infection
Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC₅₀ of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca ²⁺-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0573

Umbelliferone 5 Publications Verification 7-hydroxycoumarin; Hydrangin; NSC 19790	Monophenols Classification of Application Fields Coumarins Phenols Phenylpropanoids Endogenous metabolite Disease Research Fields Source Classification Cancer	Apoptosis Fluorescent Dye
Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-N6856

4-Hydroxycoumarin	Infection Classification of Application Fields Coumarins Phenylpropanoids Endogenous metabolite Disease Research Fields Source Classification	Bacterial Endogenous Metabolite
4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-127170

3-Hydroxycoumarin	Structural Classification other families Classification of Application Fields Other Diseases Coumarins Phenylpropanoids Plants Disease Research Fields Source Classification	Lipoxygenase Tyrosinase
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase with an IC₅₀ for recombinant human tyrosinase (rHT) of 26 μM, and a K_i of 3.39 μM; its IC₅₀ for LOX is 9.5 μM. 3-Hydroxycoumarin has DPPH free radical scavenging activity (IC₅₀ = 31.2 μM). 3-Hydroxycoumarin has photoprotective effects on sea urchin zygotes and embryos .

HY-105055

Didemnin B	Natural Products Animals Classification of Application Fields Marine natural products Other marine organisms Disease Research Fields Source Classification Cancer	Others
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

HY-133091

7-Ethoxycoumarin 7-O-Ethylumbelliferone	Citrus × aurantium Linnaeus Classification of Application Fields Rutaceae Other Diseases Coumarins Phenylpropanoids Plants Disease Research Fields Source Classification	Cytochrome P450
7-Ethoxycoumarin is a substrate of cytochrome P450 (CYP450). 7-Ethoxycoumarin has been used for the functional characterization of various CYPs and for the generation of 7-hydroxycoumarin (HY-N0573) .

HY-N6656

6-Hydroxycoumarin	Monophenols other families Classification of Application Fields Coumarins Phenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields Source Classification	Fungal Bacterial
6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity .

HY-N0573R

Umbelliferone (Standard) 7-hydroxycoumarin (Standard); Hydrangin (Standard); NSC 19790 (Standard)	Structural Classification Monophenols Coumarins Phenols Phenylpropanoids Endogenous metabolite Source Classification	Reference Standards Apoptosis Fluorescent Dye
Umbelliferone (Standard) (7-Hydroxycoumarin (Standard)) is the analytical standard of Umbelliferone (HY-N0573). This product is intended for research and analytical applications. Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats.

HY-N6856R

*4-Hydroxycoumarin* (Standard)**	Structural Classification Coumarins Phenylpropanoids Endogenous metabolite Source Classification	Reference Standards Bacterial Endogenous Metabolite
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-127170R

*3-Hydroxycoumarin* (Standard)**	Structural Classification other families Coumarins Phenylpropanoids Plants Source Classification	Lipoxygenase Reference Standards
3-Hydroxycoumarin (Standard) is the analytical standard of 3-Hydroxycoumarin. This product is intended for research and analytical applications. 3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage .

HY-133091R

7-Ethoxycoumarin (Standard) 7-O-Ethylumbelliferone (Standard)	Structural Classification Citrus × aurantium Linnaeus Rutaceae Coumarins Phenylpropanoids Plants Source Classification	Cytochrome P450 Reference Standards
7-Ethoxycoumarin (Standard) is the analytical standard of 7-Ethoxycoumarin. This product is intended for research and analytical applications. 7-Ethoxycoumarin is a substrate of cytochrome P450 (CYP450). 7-Ethoxycoumarin has been used for the functional characterization of various CYPs and for the generation of 7-hydroxycoumarin (HY-N0573) .

HY-138145

8-Acetyl-7-hydroxycoumarin	Coumarins Centella asiatica (L.) Urb. Phenylpropanoids Plants Compositae Source Classification	Fungal Bacterial
8-Acetyl-7-hydroxycoumarin is a coumarin-like compound found in Mexican patchouli (Tagetes lucida) that has anti-bacterial and anti-fungal activities .

HY-N3373R

Loganetin (Standard)	Structural Classification Human Gut Microbiota Metabolites Iridoids Cornaceae Cornus officinalis Sieb. et Zucc. Terpenoids Plants Endogenous metabolite Source Classification	Reference Standards Bacterial
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-N7650

Dihydroseselin	Classification of Application Fields Sunscreen Other Diseases Coumarins Phenylpropanoids Cosmetic Research Plants Umbelliferae Disease Research Fields Source Classification Carphephorus corymbosus (Nutt.) Torr. & A.Gray	Biochemical Assay Reagents
Dihydroseselin is a derivative of 7-hydroxycoumarin (HY-N0573). 7-hydroxycoumarin, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent

HY-N6656R

*6-Hydroxycoumarin* (Standard)**	Structural Classification Monophenols other families Coumarins Phenols Phenylpropanoids Plants Source Classification	Fungal Reference Standards Bacterial
6-Hydroxycoumarin (Standard) is the analytical standard of 6-Hydroxycoumarin (HY-N6656). This product is intended for research and analytical applications. 6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity .

HY-N18093

5-Hydroxycoumarin	Apocynaceae Structural Classification Ilex brevicuspis Reissek Coumarins Phenylpropanoids Plants Source Classification	Drug Intermediate
5-Hydroxycoumarin is a monohydroxycoumarin compound that occurs in the stems of Alyxia lucida, a plant of the genus Alyxia (Apocynaceae) .

HY-N17623

Ainsliaeasin C	Structural Classification Leibnitzia anandria (L.) Turcz. Asteraceae Coumarins Ainsliaea fragrans Champ. Phenylpropanoids Plants Compositae Source Classification	Thrombin
Ainsliaeasin C, a 7-hydroxycoumarin derivative, is an orally active anticoagulant agent that can be found in Ainsliaea fragrans. Ainsliaeasin C exerts anticoagulant activity both in vitro and in vivo. Ainsliaeasin C can be used for the research on thrombotic disorders .

HY-P2209

Nummularine B Daechuine S27; N-Demethylamphibine H	Structural Classification Alkaloids Other Alkaloids Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Rhamnaceae Source Classification	Parasite Phosphodiesterase (PDE)
Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC₅₀ of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca ²⁺-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .

Cat. No.	Product Name	Chemical Structure

HY-N0573S

Umbelliferone-d5

Umbelliferone-d₅ (7-Hydroxycoumarin-d₅) is the deuterium labeled Umbelliferone (HY-N0573 ). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

HY-143935S

*7-Hydroxycoumarin* sulfate-d5**
7-Hydroxycoumarin sulfate-d₅ is the deuterium labeled 7-Hydroxycoumarin sulfate .

HY-150662S

*2-(7-Hydroxycoumarin-4-yl)-propanoic acid methyl ester-d3*
2-(7-Hydroxycoumarin-4-yl)-propanoic acid methyl ester-d₃ is the deuterium labeled 2-(7-Hydroxycoumarin-4-yl)-propanoic acid methyl ester .

HY-W777393

Umbelliferone-13C6

Umbelliferone- ¹³C₆ (7-Hydroxycoumarin- ¹³C₆) is the ¹³C-labeled Umbelliferone (HY-N0573). Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats .

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