100 Results for "

hydroxylated

" in MedChemExpress (MCE) Product Catalog:
Products (100)

100 Results for "hydroxylated" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-17365
CAS No.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-32351
CAS No.: 19356-17-3
Synonyms: 25-Hydroxy Vitamin D3
Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-32351A
CAS No.: 63283-36-3
Synonyms: 25-hydroxy Vitamin D3 monohydrate
Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-114360
CAS No.: 2958-04-5
Purity:  99.73%
Taurohyodeoxycholic acid is an orally active 6 alpha-hydroxylated bile acid. Taurohyodeoxycholic acid decreases colonic MPO activity, TNF-α, lL-6 serum levels and the expression of COX-2. Taurohyodeoxycholic acid alleviates trinitrobenzene sulfonic acid induced ulcerative colitis via regulating Th1/Th2 and Th17/Treg cells balance. Taurohyodeoxycholic acid ameliorates high-fat diet-induced nonalcoholic fatty liver disease in mice. Taurohyodeoxycholic acid prevents Taurochenodeoxycholic acid (HY-N2027)-induced hepatotoxicity in bile fistula rats. Taurohyodeoxycholic acid can be used for the study of nonalcoholic fatty liver disease (NAFLD), colitis and biliary fistula .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-76801
CAS No.: 58050-55-8
Synonyms: 24,25-Dihydroxy vitamin D2
Research Areas:  

Metabolic Disease

24,25-Dihydroxy VD2 (24,25-Dihydroxy vitamin D2) is a hydroxylated metabolite and derivative of Vitamin D2 HY-76542 (HY-76542) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0169B
CAS No.: 668-49-5
Murideoxycholic acid is a 6 beta-hydroxylated bile acid .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-105055
CAS No.: 77327-05-0
Purity:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W399297
CAS No.: 566-17-6
Synonyms: 7α,12α-Dihydroxycholanoic acid
Isodeoxycholic acid (7α,12α-Dihydroxycholanoic acid) is a 3β-hydroxylated secondary bile acid. Isodeoxycholic acid is produced by epimerization of deoxycholic acid by intestinal bacteria. Isodeoxycholic acid is detectable in feces, mainly existing as saponifiable conjugates with long-chain fatty acids. Isodeoxycholic acid participates in the regulation of intestinal physiology .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-153100A
CAS No.: 89665-83-8
Purity:  98.87%
Target:  

Others

Research Areas:  

Others

(S)-mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S)-mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S)-mchm5U can be used for RNA modification synthesis .
loading...
    loading...
Cat. No.: HY-125586
CAS No.: 21150-22-1
Purity:  ≥96.0%
Research Areas:  

Cancer

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
loading...
    loading...
Cat. No.: HY-W001160
CAS No.: 1953-54-4
5-Hydroxyindole is an orally active hydroxylated indole and tryptophan metabolite. 5-Hydroxyindole activates α7 nicotinic acetylcholine receptors and acts on intestinal L-type calcium channels. 5-Hydroxyindole slows down the desensitization of 5-HT3 receptor-mediated ion currents in cells. 5-Hydroxyindole causes convulsions and loss of consciousness. 5-Hydroxyindole is used in the study of neuroblastoma, schizophrenia, and diseases related to intestinal motility disorders .
loading...
    loading...
Cat. No.: HY-32351S
CAS No.: 140710-94-7
Synonyms: 25-Hydroxy Vitamin D3-d3
Calcifediol-d3 is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .
loading...
    loading...
Cat. No.: HY-127112
CAS No.: 151333-45-8
Purity:  99.96%
Target:  

Drug Derivative

Research Areas:  

Others

Oleic acid alkyne is Oleic acid (HY-N1446) with an acetylene group. The terminal alkyne group can be used for click chemical ligation reactions. Oleic acid can be hydroxylated by a microsomal cytochrome P-450-dependent system (ω-OAH). Through click chemistry reactions, fluorescent or biotin-labeled oleic acid can be introduced to analyze its metabolism and biological activity.
loading...
    loading...
Cat. No.: HY-N7844
CAS No.: 4294-16-0
Synonyms: Benzyladenosine
N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma - .
loading...
    loading...
Cat. No.: HY-156106
CAS No.: 3033117-53-9
Purity:  99.78%
VHL-IN-1 (Compound 30) is an E3 ligase VHL inhibitor with a Kd value of 37 nM. VHL-IN-1 blocks VHL-mediated ubiquitination and degradation of HIF-1α. VHL-IN-1 stabilizes the protein levels of HIF-1α and hydroxylated HIF-1α, and induces the transcriptional activity of HIF-1α. VHL-IN-1 can be used for PROTAC development. VHL-IN-1 is applicable for cancer research .
loading...
    loading...
Cat. No.: HY-B1427
CAS No.: 924-49-2
Synonyms: Gamma-amino-beta-hydroxybutyric acid
Gamibetal (Gamma-amino-beta-hydroxybutyric acid) is γ-amino-β-hydroxybutyric acid (GABOB), a hydroxylated derivative of GABA (γ-aminobutyric acid). Gamibetal exhibits central inhibitory and anticonvulsant activities. Gamibetal can be used in research on epilepsy, neuralgia, and other conditions .
loading...
    loading...
Cat. No.: HY-N1513
CAS No.: 98665-19-1
Ganoderic acid H is a hydroxylated lanostane-type triterpenoid derived from Ganoderma lucidum with anticancer activity. Ganoderic acid H inhibits the constitutive transactivation activity of AP-1 and NF-κB; it also downregulates the secretion of uPA and the expression of CDK4, and suppresses the growth, adhesion, migration and invasion of cancer cells. Ganoderic acid H inhibits HIV-1 protease in vitro. Ganoderic acid H can be used in studies related to breast cancer and HIV infection .
loading...
    loading...
Cat. No.: HY-113058
CAS No.: 14292-27-4
Purity:  ≥98.0%
Category:  

Microorganisms

Target:  

Endogenous Metabolite

3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.
loading...
    loading...
Cat. No.: HY-W399311
CAS No.: 56806-74-7
Target:  

Drug Metabolite

Research Areas:  

Others

4-Hydroxyphenyl diphenyl phosphate is a hydroxylated metabolite of organophosphate flame retardant .
loading...
    loading...
Cat. No.: HY-N0685
CAS No.: 55954-61-5
Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity .
loading...
    loading...