21 Results for "

immunosuppressive properties

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "immunosuppressive properties" in MCE Product Catalog:

106
106 Publications Verification
Cat. No.: HY-13756
CAS No.: 104987-11-3
Purity:  99.93%
Synonyms: FK506; Fujimycin; FR900506
Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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106
106 Publications Verification
Cat. No.: HY-13756A
CAS No.: 109581-93-3
Purity:  99.67%
Synonyms: FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate
Tacrolimus (FK506) monohydrate, a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus monohydrate inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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5
5 Cited Publications
Cat. No.: HY-N0447
CAS No.: 23513-08-8
8-Gingerol can be found in the rhizome of ginger (Z. officinale) and has oral bioactivity. It activates TRPV1, with an EC50 value of 5.0 µM. 8-Gingerol inhibits COX-2 and also suppresses the growth of H. pylori in vitro. Additionally, 8-Gingerol exhibits anticancer, antioxidant, and anti-inflammatory properties by inhibiting the epidermal growth factor receptor (EGFR) and modulating its downstream STAT3/ERK pathway to suppress the proliferation, migration, and invasion of colorectal cancer cells. 8-Gingerol also exerts immunosuppressive effects by inhibiting oxidative stress, inducing cell cycle arrest, promoting apoptosis, and regulating autophagy. Furthermore, 8-Gingerol has cardioprotective effects. 8-Gingerol is promising for research in the fields of cancer, infection, immunosuppression, and cardiovascular diseases.
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3
3 Cited Publications
Cat. No.: HY-100711
CAS No.: 82-89-3
Purity:  99.89%
Synonyms: Prodigiosine; NSC47147
Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
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3
3 Cited Publications
Cat. No.: HY-119347
CAS No.: 41365-32-6
Purity:  ≥98.0%
Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4 + T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .
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3
3 Cited Publications
Cat. No.: HY-100711A
CAS No.: 56144-17-3
Purity:  98.00%
Synonyms: Prodigiosine hydrochloride
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
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1
1 Cited Publications
Cat. No.: HY-13756S
CAS No.: 1356841-89-8
Purity:  98.36%
Synonyms: FK506-13C,d2; Fujimycin-13C,d2; FR900506-13C,d2
Tacrolimus- 13C,d2 (FK506- 13C,d2) is the 13C, deuterated-labeled Tacrolimus (HY-13756). Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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1
1 Cited Publications
Cat. No.: HY-119996A
CAS No.: 2250019-94-2
Purity:  98.2%
Research Areas:  

Inflammation/Immunology

AR-C141990 hydrochloride is a potent lactate transporters (monocarboxylate transporters; MCTs) inhibitor with pKi values of 7.6, 6.6 for MCT-1 and MCT-2, respectively . AR-C141990 hydrochloride has immunosuppressive properties and inhibits graft versus host response .
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Cat. No.: HY-13756R
CAS No.: 104987-11-3
Synonyms: FK506 (Standard); Fujimycin (Standard); FR900506 (Standard)
Tacrolimus (Standard) (FK506 (Standard); Fujimycin (Standard); FR900506 (Standard)) is the analytical standard of Tacrolimus (HY-13756). This product is intended for research and analytical applications. Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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Cat. No.: HY-13751
CAS No.: 132173-07-0
Purity:  99.86%
Target:  

Sigma Receptor

Research Areas:  

Inflammation/Immunology

SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase .
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Cat. No.: HY-13756S2
Synonyms: FK506-d3; Fujimycin-d3; FR900506-d3
Tacrolimus-d3 (FK506-d3) is the deuterated-labeled Tacrolimus (HY-13756). Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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Cat. No.: HY-N8541
CAS No.: 481-70-9
Category:  

Quinones Microorganisms

Target:  

Endogenous Metabolite

Endocrocin, an anthraquinone, is a fungal secondary metabolite. Endocrocin is a potent chemotaxis inhibitor with immunosuppressive properties .
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Cat. No.: HY-W329824
CAS No.: 1158-80-1
Target:  

Others

Research Areas:  

Others

Spirazidine is a derivative of N , N -dispirotripiperazinium, with immunosuppressive properties .
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Cat. No.: HY-13751A
CAS No.: 132173-06-9
Target:  

Sigma Receptor

Research Areas:  

Inflammation/Immunology

SR-31747 free base is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase .
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Cat. No.: HY-113627
CAS No.: 52340-48-4
Undecylprodigiosin, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin shows immunosuppressive, anticancer properties and antimicrobial activities .
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Cat. No.: HY-113627A
CAS No.: 56247-02-0
Undecylprodigiosin hydrochloride, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin hydrochloride can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin hydrochloride shows immunosuppressive, anticancer properties and antimicrobial activities .
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Cat. No.: HY-114602
CAS No.: 216685-07-3
Research Areas:  

Inflammation/Immunology

AR-C117977 is a potent monocarboxylate transporter (MCT1) inhibitor. AR-C117977 prolongs the survival of skin and heart sllograft. AR-C117977 inhibits the development of transplant arteriosclerosis in aortic allografts partially, but was unable to inhibit alloantibody production after transplantation. AR-C117977 shows potent immunosuppressive properties in vivo effectively preventing acute but not chronic allograft rejection in the mouse .
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Cat. No.: HY-119347R
CAS No.: 41365-32-6
Cirsilineol (Standard) is the analytical standard of Cirsilineol. This product is intended for research and analytical applications. Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .
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Cat. No.: HY-114719
CAS No.: 117009-82-2
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

A 854777 is a homologous piperazine derivative with anti-inflammatory activity. A 854777 has non-classical immunosuppressive properties. A 854777 can be used to suppress diseases associated with inflammation .
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Cat. No.: HY-P991776

Target:  

VISTA

Research Areas:  

Inflammation/Immunology

Anti-Mouse VISTA Antibody (8G8) reacts with mouse VISTA. Anti-Mouse VISTA Antibody (8G8) is an agonistic antibody with immunosuppressive properties. Recommend Isotype Controls: Polyclonal Armenian hamster IgG, Isotype Control (HY-P990305) .
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