132173-07-0
132173-07-0
Chemical Structure
SR-31747
- CAS No.: 132173-07-0
- Formula:C23H35Cl2N
- Molecular Weight:396.44
IUPAC Name: (Z)-N-(3-(3-chloro-4-cyclohexylphenyl)allyl)-N-ethylcyclohexanamine hydrochloride
InChIKey: HKHPCMBPASXYGP-KVVVOXFISA-N
SMILES: CCN(C/C=C\C1=CC=C(C2CCCCC2)C(Cl)=C1)C3CCCCC3.Cl
Biological Activity: SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SR-31747 | 99.66% | SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-13751ASR-31747 free base -
Similarity Score 0.55
HY-101581Bucloxic acid -
Similarity Score 0.52
HY-121292Clidanac -
Similarity Score 0.49
HY-B1277Trihexyphenidyl hydrochloride -
Similarity Score 0.49
HY-146413HF50731 -
Similarity Score 0.48
HY-15997(-)-U-50488 hydrochloride -
Similarity Score 0.48
HY-15997A(+)-U-50488 hydrochloride -
Similarity Score 0.48
HY-108511APB28 -
Similarity Score 0.48
HY-1688063-Chloro PCP hydrochloride -
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References
- [1]. Derocq JM, et al. In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the sigma ligand SR 31747. J Pharmacol Exp Ther. 1995 Jan;272(1):224-30. [Content Brief]
- [2]. Silve S, et al. The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae. Mol Cell Biol. 1996 Jun;16(6):2719-27. [Content Brief]
