1. GPCR/G Protein
    Immunology/Inflammation
    Anti-infection
  2. CXCR
    HIV
  3. HF50731

HF50731 

Cat. No.: HY-146413
Handling Instructions

HF50731 (compound 21) is a potent CXCR4 antagonist. HF50731 shows strong CXCR4 binding affinity, with IC50 of 19.8 nM. HF50731 effectively inhibits calcium mobilization, cell migration, and HIV-1 infection via CXCR4 coreceptor, with IC50 values of 119.2 nM, 621.4 nM and 1.5 μM.

For research use only. We do not sell to patients.

HF50731 Chemical Structure

HF50731 Chemical Structure

CAS No. : 2484771-19-7

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Description

HF50731 (compound 21) is a potent CXCR4 antagonist. HF50731 shows strong CXCR4 binding affinity, with IC50 of 19.8 nM. HF50731 effectively inhibits calcium mobilization, cell migration, and HIV-1 infection via CXCR4 coreceptor, with IC50 values of 119.2 nM, 621.4 nM and 1.5 μM[1].

IC50 & Target

CXCR4

19.8 nM (IC50)

HIV-1

1.5 μM (IC50)

Molecular Weight

414.67

Formula

C26H46N4

CAS No.
SMILES

C1(CNCCCNC2CCCCC2)=CC=C(CNCCCNC3CCCCC3)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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HF50731
Cat. No.:
HY-146413
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