109581-93-3
Chemical Structure
Tacrolimus monohydrate
Synonym(s): FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate
- CAS No.: 109581-93-3
- Formula:C44H71NO13
- Molecular Weight:822.03
InChIKey: NWJQLQGQZSIBAF-MLAUYUEBSA-N
SMILES: O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O.O
Biological Activity: Tacrolimus (FK506) monohydrate, a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus monohydrate inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties[1][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tacrolimus monohydrate | 99.93% | Tacrolimus (FK506) monohydrate, a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus monohydrate inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. | ||||||||||||||||||||
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Keywords
