Tsukubamycin B
Based on 1 Customer Validation
Tsukubamycin B is discovered from Streptomyces tsukubaensis and exhibits immunosuppressive activity by inhibiting T-cell activation. Tsukubamycin B can be used for immune rejection reaction research.
For research use only. We do not sell to patients.
- Purity: 95.59%
- CAS No.: 104987-30-6
- Formula: C44H71NO12
- Molecular Weight:806.03
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| T-cell | IC50 |
0.93 nM
Compound: 4
|
Agonistic activity in a murine splenic T-cell proliferation assay was calculated by measurement of [3H]thymidine uptake relative to control
Agonistic activity in a murine splenic T-cell proliferation assay was calculated by measurement of [3H]thymidine uptake relative to control
|
10.1016/S0960-894X(01)81248-8 |
Chemical Information
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CAS No. 104987-30-6
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Appearance Solid
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Molecular Weight 806.03
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Formula C44H71NO12
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SMILES
CO[C@@H]1[C@]2([H])O[C@]([C@@H](C1)C)(C(C(N3[C@](CCCC3)([H])C(O[C@@H]([C@@H]([C@H](CC([C@@H](/C=C(C[C@@H](C[C@@H]2OC)C)\C)CCC)=O)O)C)/C(C)=C/[C@H]4C[C@H]([C@@H](CC4)O)OC)=O)=O)=O)O
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Structure Classification
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Initial Source
Streptomyces tsukubaensis
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (272 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)