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Results for "

importin-β

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101091
    Importazole
    15+ Cited Publications

    		 Apoptosis Cancer
    Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.
    Importazole
  • HY-13691
    MKC-1

    Ro-31-7453

    		 Apoptosis Akt mTOR Microtubule/Tubulin Mitosis Cancer
    MKC-1 (Ro-31-7453) is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin and members of the importin β family .
    MKC-1
  • HY-13691R
    MKC-1 (Standard)

    Ro-31-7453 (Standard)

    		 Apoptosis Akt mTOR Microtubule/Tubulin Mitosis Reference Standards Cancer
    MKC-1 (Standard) is the analytical standard of MKC-1. This product is intended for research and analytical applications. MKC-1 (Ro-31-7453) is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin and members of the importin β family .
    MKC-1 (Standard)
  • HY-101091R
    Importazole (Standard)

    		Apoptosis Reference Standards Cancer
    Importazole (Standard) is the analytical standard of Importazole (HY-101091). This product is intended for research and analytical applications. Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.
    Importazole (Standard)
  • HY-182566
    ITI-367

    		HIV Infection
    ITI-367 is a HIV-1 inhibitor that targets the nuclear localization signal 1 (NLS-1) of HIV-1 matrix protein and the interaction between HIV-1 pre-integration complex (PIC) and importin-β. ITI-367 inhibits HIV-1 replication at the pre-integration stage, reduces the formation of 2-LTR circles, and sequesters viral DNA in the cytoplasm. ITI-367 can be used for the research of HIV infection .
    ITI-367

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