1 Result for "

iso-WAY-260022

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "iso-WAY-260022" in MCE Product Catalog:

Cat. No.: HY-10427A
CAS No.: 1214914-38-1
Synonyms: iso-NRI-022
iso-WAY-260022 (Compound 13R) is an orally active, brain-penetrant and selective norepinephrine transporter (hNET) inhibitor with an IC50 value of 140 nM. iso-WAY-260022 also shows inhibitory effects on human serotonin (hSERT) and dopamine transporters (hDAT). iso-WAY-260022 inhibits norepinephrine reuptake and increases hypothalamic norepinephrine levels to regulate thermoregulatory center function. iso-WAY-260022 is promising for research of vasomotor symptoms, such as menopausal hot flushes, night sweats .
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