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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
71 Results for "
luminal
" in MedChemExpress (MCE) Product Catalog:
Products (71)
71 Results for "luminal" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: DCC-2036
Rebastinib (DCC-2036) is an orally active, non-ATP-competitive Bcr-Abl inhibitor, with IC50 values of 0.8 nM and 4 nM against Abl1 WT and Abl1 T315I, respectively. Rebastinib potently inhibits CYP2C8 (IC50 = 0.0533 μM) and CYP2C9 (IC50 = 2.54 μM). Rebastinib allosterically inhibits Tie2 with an IC50 of 0.63 nM. Rebastinib inhibits the transcriptional activity of FoxO1. Rebastinib inhibits SRC family kinases, KDR and FLT3 kinases. Rebastinib induces Apoptosis. Rebastinib exerts anti-tumor activity in breast cancer. Rebastinib exerts anti-angiogenic effects. Rebastinib increases myotube diameter and improves reduced contractility. Rebastinib can be used in research related to triple-negative breast cancer, luminal breast cancer, pancreatic neuroendocrine tumors, muscle atrophy, cancer cachexia, chronic myeloid leukemia, and B-lymphocytic leukemia .
10
10 Cited Publications
Synonyms: Prostaglandin F2α; PGF2α
10
10 Cited Publications
Synonyms: Prostaglandin F2α tromethamine salt; PGF2α THAM; Prostaglandin F2α THAM
5
5 Cited Publications
Cat. No.: HY-P7503
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANG; Angiogenin, Ribonuclease, RNase A Family, 5; Angiogenin; Ribonuclease A Family Member 5; RNASE5; RNase 5; Ribonuclease 5; Epididymis luminal Protein 168; HEL168; Ribonuclease A A1; RAA1; RNASE4; Homo Sapiens Epididymis luminal Protein 168; ALS9
Species:
Human
Source:
E. coli
3
3 Cited Publications
3
3 Cited Publications
Cat. No.: HY-118315
CAS No.: 143323-55-1
Target:
Research Areas:
L-012 is a luminal-based chemiluminescent probe. L-012 sodium salt can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)) .
3
3 Cited Publications
Cat. No.: HY-P73915A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HSPA8; Epididymis Secretory Sperm Binding Protein Li 72p; Prev. HSPA10; Constitutive Heat Shock Protein 70; HSC70; Epididymis luminal Protein 33; HSP73; Heat Shock Cognate Protein 54; Heat Shock Cognate 71 KDa Protein; Heat Shock 70kd Protein 10; HSC71; H
Species:
Human
Source:
E. coli
2
Target:
Research Areas:
Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .
1
1 Cited Publications
Cat. No.: HY-D1694
CAS No.: 1064123-31-4
1
1 Cited Publications
Cat. No.: HY-P73580
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TTR; Transthyretin; PALB; CTS1; HsT2651; CTS; Prealbumin, Amyloidosis Type I; ATTR; TBPA; Epididymis luminal Protein 111; Thyroxine-Binding Prealbumin; Carpal Tunnel Syndrome 1; TTR Protein; Prealbumin; AMYLD1; HEL111; TTN
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P78746
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA2; CAC; Carbonic Anhydrase 2; Epididymis Secretory Protein Li 282; Carbonic Anhydrase II; Epididymis luminal Protein 76; CA-II; Carbonic Anhydrase B; Carbonate Dehydratase II; Carbonic Dehydratase; Cyanamide Hydratase CA2; Carbonic Anhydrase; CAII; HEL-
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P703226
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSP90B1; HEL35; Prev. TRA1; Heat Shock Protein 90kDa Beta Family Member 1; Endoplasmin; Stress-Inducible Tumor Rejection Antigen Gp96; GRP94; Endothelial Cell (HBMEC) Glycoprotein; Heat Shock Protein 90 KDa Beta Member 1; Epididymis luminal Protein 35; GP
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73915
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPA8; Epididymis Secretory Sperm Binding Protein Li 72p; Prev. HSPA10; Constitutive Heat Shock Protein 70; HSC70; Epididymis luminal Protein 33; HSP73; Heat Shock Cognate Protein 54; Heat Shock Cognate 71 KDa Protein; Heat Shock 70kd Protein 10; HSC71; Heat Shock 70kD Protein 8; Lipopolysaccharide-Associated Protein 1; HSPA8 Protein; Heat Shock Protein Family A Member 8; CDNA FLJ77848; Heat Shock 70 KDa Protein 8; HEL-S-72p; Heat Shock 70kDa Protein 8; HSC54; LPS-Associated Protein 1; HSP71; HEL-33; NIP71; LAP-1; LAP1; Heat Shock Protein Family A (Hsp70) Member 8; N-Myristoyltransferase Inhibitor Protein 71
Species:
Human
Source:
E. coli
Cat. No.: HY-N16308
CAS No.: 3091879-77-2
Category:
Target:
Cat. No.: HY-12956S
CAS No.: 34210-11-2
Synonyms: Prostaglandin F2a-d4; PGF2α-d4
Diloxanide is an anti-protozoal agent and can be used for the research of asymptomatic-intestinal amebiasis caused by Entamoeba histolytica or some other protozoal infections. Diloxanide is an active luminal amebicide and hydrolyzed in the gastrointestinal tract from its proagent Diloxanide furoate (HY-B1147) .
Cat. No.: HY-N7761
CAS No.: 126979-84-8
Synonyms: Tetrahydro tanshinone I
Trijuganone B (Tetrahydro tanshinone I) is a naturally occurring covalent pan-inhibitor of gut microbial bile salt hydrolases that can be isolated from Salvia trijuga. Trijuganone B inhibits total gut microbial bile salt hydrolase activity in live microorganisms and murine gut luminal content. Trijuganone B can be used for the research of bile-acid-related metabolic disorders .
Cat. No.: HY-W018397
CAS No.: 5541-67-3
Synonyms: NSC 130828
Tiliquinol (NSC 130828) is a non-absorbed anti-amoebic luminal agent. Tiliquinol is used in combination with tibroquinol. Tiliquinol can be used for the research of amebic liver abscess .
Cat. No.: HY-W711035
CAS No.: 137641-05-5
Synonyms: AC 900001
Research Areas:
Picolinafen is a pyridine-class herbicide that acts as a phytoene desaturase (PDS) inhibitor. Picolinafen effectively controls broadleaf weeds and disrupts carotenoid biosynthesis. Picolinafen exhibits cytotoxicity to porcine trophectoderm (pTr) and luminal epithelial (pLE) cells. Picolinafen induces (ROS accumulation, calcium depletion, and activates (MAPK and PI3K signaling pathways, leading to decreased cell viability, increased apoptosis, impaired migration, and altered expression of implantation-related genes. Picolinafen has an LD50 value of 2.7 mg/kg in mammals and 7 μg/L in fish. Picolinafen exhibits toxic effects during zebrafish embryogenesis [1][2].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
