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  2. Parasite
  3. Diloxanide

Diloxanide 

Cat. No.: HY-119972
Handling Instructions

Diloxanide is an anti-protozoal agent and can be used for the research of asymptomatic-intestinal amebiasis caused by Entamoeba histolytica or some other protozoal infections. Diloxanide is an active luminal amebicide and hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate (HY-B1147).

For research use only. We do not sell to patients.

Diloxanide Chemical Structure

Diloxanide Chemical Structure

CAS No. : 579-38-4

Size Price Stock Quantity
50 mg USD 100 In-stock
Estimated Time of Arrival: December 31
100 mg USD 170 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
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Based on 1 publication(s) in Google Scholar

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Description

Diloxanide is an anti-protozoal agent and can be used for the research of asymptomatic-intestinal amebiasis caused by Entamoeba histolytica or some other protozoal infections. Diloxanide is an active luminal amebicide and hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate (HY-B1147)[1].

In Vivo

Diloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate[1].
Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats[2].

Molecular Weight

234.08

Formula

C₉H₉Cl₂NO₂

CAS No.

579-38-4

SMILES

O=C(C(Cl)Cl)N(C)C1=CC=C(C=C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

DiloxanideParasiteanti-protozoalEntamoeba histolyticainfectionluminal amebicideamoebic colitisInhibitorinhibitorinhibit

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Diloxanide
Cat. No.:
HY-119972
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