4 Results for "

lysosomal glycogen

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "lysosomal glycogen" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-E70183
Synonyms: EC:3.2.1.20; GAA
Lysosomal α-Glucosidase (EC:3.2.1.20) is a lysosomal α-Glucosidase that degrades glycogen into glucose and catalyzes the hydrolysis of α-1,4 and α-1,6 glycosidic linkages in glycogen, as well as that of natural and synthetic oligoglucosides. Deficiency of Lysosomal α-Glucosidase causes type II glycogen storage disease (Pompe disease), which is characterized by lysosomal glycogen accumulation in mammals and birds. Lysosomal α-Glucosidase can be used in research related to type II glycogen storage disease .
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Cat. No.: HY-P99803
CAS No.: 2145123-44-8
Synonyms: VAL-1221

Target:  

Glycosidase

Research Areas:  

Others

Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research .
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Cat. No.: HY-108828
CAS No.: 420784-05-0
Synonyms: rhGAA
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

Alglucosidase alfa (rhGAA) is a recombinant human acid α-glucosidase. Alglucosidase alfa is taken up by cells via the cation-independent mannose-6-phosphate receptor (CI-MPR) pathway and transported to lysosomes, where GAA degrades glycogen in the acidic lysosomal environment. Alglucosidase alfa is applicable to research related to lysosomal glycogen metabolism and glycogen storage diseases .
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Cat. No.: HY-P810401
Synonyms: 70 kDa lysosomal alpha-glucosidase, Acid alpha glucosidase, Acid maltase, Aglucosidase alfa, Alpha glucosidase, GAA, Glucosidase alpha acid (Pompe disease glycogen storage disease type II), Glucosidase alpha acid, Glucosidase alpha, LYAG

Host:  

Rabbit

Application:  

WB, IF-Tissue, IHC-P

Reactivity:  

Human

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