31 Results for "

mitochondrial imaging

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "mitochondrial imaging" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-139109
CAS No.: 115970-66-6
Purity:  99.87%
Synonyms: ADS 780WS
IR-783 (ADS 780WS) is a heptamethine cyanine dye. IR-783 induces Mitochondrial membrane potential loss, ATP depletion, mitochondrial permeability transition pore opening, Cytochrome c release and Apoptosis in breast cancer cells. IR-783 promotes the translocation of Drp1 from the cytosol to mitochondria. IR-783 increases the expression of mitochondrial fission proteins such as MFF and Fission-1. IR-783 possesses imaging, cancer-targeting and anticancer properties. IR-783 exerts anticancer effects against breast cancer. IR-783 can be used in breast cancer-related research .
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3
3 Cited Publications
Cat. No.: HY-D2346
HBmito Crimson is a deep red fluorescent probe (λex: 658 nm, λem: 678 nm) for the inner mitochondrial membrane. HBmito Crimson is a cell membrane-permeable probe with high selectivity for the mitochondrial inner membrane, suitable for specific fluorescence staining of the inner mitochondrial membrane in living cells. HBmito Crimson has high photostability and brightness, suitable for long-term dynamic fluorescence imaging.
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2
2 Cited Publications
Cat. No.: HY-D1250
CAS No.: 1859102-62-7
Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells .
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Cat. No.: HY-B0926
CAS No.: 117-96-4
Synonyms: Diatrizoate; Amidotrizoic acid
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Diatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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Cat. No.: HY-B0926A
CAS No.: 737-31-5
Synonyms: Diatrizoic acid sodium salt; Sodium amidotrizoate
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Sodium diatrizoate (Diatrizoic acid sodium salt) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Sodium diatrizoate induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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Cat. No.: HY-W094758A
CAS No.: 959-81-9
4-Di-1-ASP is a styryl dye used to stain glioma cells in living brain tissue for analysis of cell structure, viability, proliferation and endocytosis, cytokinesis and phagocytosis, as well as for observation of mitochondrial structures in living cells. 4-Di-1-ASP fluoresces green when imaged microscopically (λexem = 475/606 nm) .
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Cat. No.: HY-76573
CAS No.: 1216897-16-3
Target:  

Apoptosis

Research Areas:  

Cardiovascular Disease Cancer

ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential .
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Cat. No.: HY-128536
CAS No.: 2436544-28-2
KMG-104AM is a Mg 2+ fluorescent probe. KMG-104AM is a membrane-permeable ester-modified derivative of KMG-104, which serves as a reporter and imaging agent. KMG-104AM can track the increase in intracellular free magnesium ion concentration induced by mitochondrial uncoupling. KMG-104AM enables visualization of the three-dimensional distribution of intracellular magnesium ion concentration. KMG-104AM is applicable to research related to the functions of intracellular magnesium ions .
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Cat. No.: HY-150175
CAS No.: 1786411-17-3
Target:  

Fluorescent Dye

Research Areas:  

Inflammation/Immunology

HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O2 •−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O2 •−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O2 •− roles in inflammation, mitochondrial stress, and other physiological processes .
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Cat. No.: HY-B0926AR
CAS No.: 737-31-5
Synonyms: Diatrizoic acid sodium salt (Standard); Sodium amidotrizoate (Standard)
Research Areas:  

Inflammation/Immunology

Sodium diatrizoate (Standard) is the analytical standard of Sodium diatrizoate. This product is intended for research and analytical applications. Sodium diatrizoate (Diatrizoic acid sodium salt) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Sodium diatrizoate induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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Cat. No.: HY-B0926R
CAS No.: 117-96-4
Synonyms: Diatrizoate (Standard); Amidotrizoic acid (Standard)
Research Areas:  

Inflammation/Immunology

Diatrizoic acid (Standard) is the analytical standard of Diatrizoic acid. This product is intended for research and analytical applications. Diatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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Cat. No.: HY-D2279
NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .
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Cat. No.: HY-B0926S
CAS No.: 1189668-69-6
Synonyms: Diatrizoate-d6; Amidotrizoic acid-d6
Diatrizoic acid-d6 (Diatrizoate-d6; Amidotrizoic acid-d6) is the deuterium labeled Diatrizoic acid (HY-B0926). Diatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
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Cat. No.: HY-136675
CAS No.: 1850419-05-4
Target:  

Fluorescent Dye

Research Areas:  

Others

ASMI is a ratiometric, two-photon excited fluorescent probe, composed of a highly two-photon active and biocompatible merocyanine fluorophore and an acrylate moiety as a thiol reactive site. ASMI is able to selectively detect and monitor mitochondrial Cys with rapid responsiveness, imaging living cells and intact tissues with high contrast and brightness at a depth of 150 μm. The two-photon action cross section (Φσmax) of ASMI is 65.2 GM, corresponding to an excitation wavelength (λex) of 740 nm.
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Cat. No.: HY-D3148
CAS No.: 1804107-88-7
Target:  

Fluorescent Dye

Research Areas:  

Others

TPE-Ph-In is a mitochondria-targeted voltage-sensitive probe that can be used for mitochondrial membrane potential detection, mitochondrial imaging of animal and plant cells and tissues, mouse sperm activity indication, and detection of mitochondrial membrane potential changes associated with early apoptosis. TPE-Ph-In is non-fluorescent in solution, but emits strong fluorescence when aggregated via restriction of intramolecular rotation/movement, and its fluorescence intensity is directly correlated with local probe concentration or mitochondrial membrane potential level. TPE-Ph-In can penetrate cell membranes, target mitochondria through charge-dependent accumulation, has low cytotoxicity and high photostability, and enables super-resolution imaging of plant mitochondrial fission, fusion and cristae structures. The excitation wavelengths of TPE-Ph-In include 450 nm, 488 nm, and 489 nm, while its emission wavelengths include 551-661 nm, 660 nm, and 694 nm. TPE-Ph-In can be used for studies on mitochondrial dysfunction associated with early apoptosis .
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Cat. No.: HY-D3240
CAS No.: 2375541-43-6
Photoactive NTR probe (Compound 1) is a covalent crosslinker and Fluorescent indicator targeting Nitroreductase. The Photoactive NTR probe undergoes a sequential activation process: it is first activated via nitroreductase-mediated nitro-to-amino conversion, and then forms a fluorescent product upon photoactivation. The Photoactive NTR probe can form covalent adducts with the side chains of cysteine, tyrosine, lysine and histidine in adjacent proteins to reduce fluorophore diffusion. The Photoactive NTR probe enables super-resolution (STORM) imaging of active mitochondrial nitroreductase microdomains in living cells .
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Cat. No.: HY-D3132
CAS No.: 1616505-01-1
Target:  

Fluorescent Dye

Research Areas:  

Others

Spring Red is a fluorescent probe for mitochondrial pH detection (Ex/Em = 530/680 nm) that can be taken up by live cells and mitochondria. The detection mechanism of Spring Red depends on pH changes and mitochondrial membrane potential. Fluorescence intensity increases with elevated pH, and a significant pH-dependent fluorescent response is observed in the pH range of 5.0‑8.0. Spring Red is suitable for long-term live-cell imaging and in vivo imaging, and can be used to monitor dynamic mitochondrial pH changes .
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Cat. No.: HY-D3512
MitoLumina 780 is a mitochondria-targeting fluorescent probe used to label mitochondria in live cells. MitoLumina 780 contains a chloromethyl group that allows for covalent binding to mitochondrial thiol-containing proteins. MitoLumina 780 is primarily used for mitochondrial imaging, live-cell mitochondrial tracking, and multicolor fluorescence microscopy (Ex/Em = 778/805 nm).
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Cat. No.: HY-D3513
MitoLumina 750 is a mitochondria-targeting fluorescent probe used to label mitochondria in live cells. MitoLumina 750 contains a chloromethyl group that allows for covalent binding to mitochondrial thiol-containing proteins. MitoLumina 750 is primarily used for mitochondrial imaging, live-cell mitochondrial tracking, and multicolor fluorescence microscopy (Ex/Em = 745/775 nm).
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Cat. No.: HY-D3514
MitoLumina 680 is a mitochondria-targeting fluorescent probe used to label mitochondria in live cells. MitoLumina 680 contains a chloromethyl group that allows for covalent binding to mitochondrial thiol-containing proteins. MitoLumina 680 is primarily used for mitochondrial imaging, live-cell mitochondrial tracking, and multicolor fluorescence microscopy (Ex/Em = 678/700 nm).
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