117-96-4
Chemical Structure
Diatrizoic acid
Synonym(s): Diatrizoate; Amidotrizoic acid
- CAS No.: 117-96-4
- Formula:C11H9I3N2O4
- Molecular Weight:613.91
IUPAC Name: 3,5-diacetamido-2,4,6-triiodobenzoic acid
InChIKey: YVPYQUNUQOZFHG-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(I)C(NC(C)=O)=C(I)C(NC(C)=O)=C1I
Biological Activity: Diatrizoic acid (Diatrizoate) is an iodinated contrast agent. Diatrizoic acid induces intracellular calcium homeostasis dysregulation, activates calpain and caspase-12, and activates the executor caspase-3, inducing cell apoptosis. Diatrizoic acid induces mitophagy, oxidative stress, and TNFα secretion/inflammatory responses, while inhibiting mitochondrial respiratory function. Diatrizoic acid can be used for research on contrast-induced acute kidney injury (ci-aki)[1].
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Diatrizoic acid | 99.73% | Diatrizoic acid (Diatrizoate) is an iodinated contrast agent. Diatrizoic acid induces intracellular calcium homeostasis dysregulation, activates calpain and caspase-12, and activates the executor caspase-3, inducing cell apoptosis. Diatrizoic acid induces mitophagy, oxidative stress, and TNFα secretion/inflammatory responses, while inhibiting mitochondrial respiratory function. Diatrizoic acid can be used for research on contrast-induced acute kidney injury (ci-aki). | ||||||||||||||||||||
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Diatrizoic acid (Standard) | ≥98% | Diatrizoic acid (Standard) (Diatrizoate (Standard); Amidotrizoic acid (Standard)) is the analytical standard of Diatrizoic acid (HY-B0926). This product is intended for research and analytical applications. Diatrizoic acid (Diatrizoate) is an iodinated contrast agent. Diatrizoic acid induces intracellular calcium homeostasis dysregulation, activates calpain and caspase-12, and activates the executor caspase-3, inducing cell apoptosis. Diatrizoic acid induces mitophagy, oxidative stress, and TNFα secretion/inflammatory responses, while inhibiting mitochondrial respiratory function. Diatrizoic acid can be used for research on contrast-induced acute kidney injury (ci-aki). | ||||||||||||||||||||
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Diatrizoic acid-d6 | Diatrizoic acid-d6 (Diatrizoate-d6; Amidotrizoic acid-d6) is the deuterated-labeled Diatrizoic acid (HY-B0926). Diatrizoic acid (Diatrizoate) is an iodinated contrast agent. Diatrizoic acid induces intracellular calcium homeostasis dysregulation, activates calpain and caspase-12, and activates the executor caspase-3, inducing cell apoptosis. Diatrizoic acid induces mitophagy, oxidative stress, and TNFα secretion/inflammatory responses, while inhibiting mitochondrial respiratory function. Diatrizoic acid can be used for research on contrast-induced acute kidney injury (ci-aki). | |||||||||||||||||||||
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Similarity Score 0.88
HY-B0926ASodium diatrizoate -
Similarity Score 0.84
HY-B1699Metrizoic acid -
Similarity Score 0.83
HY-W153917Diatrizoic acid EP impurity A -
Similarity Score 0.82
HY-B1053Iotalamic acid -
Similarity Score 0.76
HY-B1406Acetrizoic acid -
Similarity Score 0.76
HY-125695Loxitalamic acid -
Similarity Score 0.74
HY-B1053BIothalamate sodium -
Similarity Score 0.72
HY-B0926BDiatrizoate meglumine -
Similarity Score 0.72
HY-B1053SIotalamic acid-d3 -
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