Diatrizoic acid-d6
Diatrizoic acid-d6 (Diatrizoate-d6; Amidotrizoic acid-d6) is the deuterated-labeled Diatrizoic acid (HY-B0926). Diatrizoic acid (Diatrizoate) is an iodinated contrast agent. Diatrizoic acid induces intracellular calcium homeostasis dysregulation, activates calpain and caspase-12, and activates the executor caspase-3, inducing cell apoptosis. Diatrizoic acid induces mitophagy, oxidative stress, and TNFα secretion/inflammatory responses, while inhibiting mitochondrial respiratory function. Diatrizoic acid can be used for research on contrast-induced acute kidney injury (ci-aki).
For research use only. We do not sell to patients.
- CAS No.: 1189668-69-6
- Formula: C11H3D6I3N2O4
- Molecular Weight:619.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
[1]|
Caspase-12 |
calpain |
Caspase-3 |
TNFα |
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1189668-69-6
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Unlabeled CAS 117-96-4
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Molecular Weight 619.95
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Formula C11H3D6I3N2O4
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SMILES
[2H]C([2H])([2H])C(NC1=C(C(C(O)=O)=C(C(NC(C([2H])([2H])[2H])=O)=C1I)I)I)=O
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Synonyms
Diatrizoate-d6; Amidotrizoic acid-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Diatrizoic acid-d6 Related Classifications
HY-B0926S Related Classifications
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Keywords
- Diatrizoic acid-d6
- 1189668-69-6
- Diatrizoate-d6
- Amidotrizoic acid-d6
- Isotope-Labeled Compounds
- Apoptosis
- Calpain
- Caspase
- Mitophagy
- TNF Receptor
- calcium-activated neutral cysteine protease
- Mitochondrial Autophagy
- Tumor Necrosis Factor Receptor
- TNFR
- apoptosis
- calpain
- caspase-12
- caspase-3
- contrast-induced acute kidney injury
- intracellular calcium dysregulation
- mitophagy
- oxidative stress
- radiographic airway imaging
- radiopaque contrast agent
- Inhibitor
- inhibitor
- inhibit