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Sodium diatrizoate (Synonyms: Diatrizoic acid sodium salt; Sodium amidotrizoate)

Cat. No.: HY-B0926A Purity: >98.0%
Handling Instructions

Sodium diatrizoate is an iodinated radiocontrast agent.

For research use only. We do not sell to patients.

Sodium diatrizoate Chemical Structure

Sodium diatrizoate Chemical Structure

CAS No. : 737-31-5

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of Sodium diatrizoate:

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  • Protocol

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  • Purity & Documentation

  • References

Description

Sodium diatrizoate is an iodinated radiocontrast agent.

In Vivo

Sodium diatrizoate is an iodinated radiocontrast agent. Histological examination of rat lung tissue shows no acute toxicity or inflammation after insufflation of Sodium diatrizoate nanoparticle agglomerates. Sodium diatrizoate nanoparticle agglomerates offers a promising radiocontrast agent for safe and effective lung visualization[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (157.26 mM; Need ultrasonic)

H2O : ≥ 50 mg/mL (78.63 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5726 mL 7.8629 mL 15.7257 mL
5 mM 0.3145 mL 1.5726 mL 3.1451 mL
10 mM 0.1573 mL 0.7863 mL 1.5726 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Animal Administration
[1]

Female Sprague-Dawley rats (200 to 250 grams) are housed in temperature and humidity controlled rooms with free access to food and water and maintained on a 12 h light/dark cycle. Rats are anesthetized by a 67.5 mg/kg ketamine, 3.5 mg/kg xylazine and 0.66 mg/kg acepromazine subcutaneous cocktail. While under anesthesia, rats are placed on a heating pad to maintain a body temperature of 37°C. Sodium diatrizoate nanoparticle agglomerates (10 mg) is administered by intratracheal insufflation using a dry powder insufflator. At the end of the experiment, the rats are euthanized by isoflurane inhalation overdose followed by harvest of major organs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

635.90

Formula

C₁₁H₈I₃N₂NaO₄

CAS No.

737-31-5

SMILES

O=C([O-])C1=C(I)C(NC(C)=O)=C(I)C(NC(C)=O)=C1I.[Na+]

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Sodium diatrizoate
Cat. No.:
HY-B0926A
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Sodium diatrizoate

Cat. No.: HY-B0926A