115970-66-6
Chemical Structure
IR-783
Synonym(s): ADS 780WS
- CAS No.: 115970-66-6
- Formula:C38H46ClN2NaO6S2
- Molecular Weight:749.35
IUPAC Name: sodium 4-((Z)-2-((E)-2-(2-chloro-3-((E)-2-(3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium-2-yl)vinyl)cyclohex-2-en-1-ylidene)ethylidene)-3,3-dimethylindolin-1-yl)butane-1-sulfonate
InChIKey: QQIQAVJARACLHE-UHFFFAOYSA-M
SMILES: O=[S](CCCCN(/C1=C\C=C(CCC2)\C(Cl)=C2/C=C/C(C3(C)C)=[N+](C4=CC=CC=C34)CCCC[S](=O)([O-])=O)C5=CC=CC=C5C1(C)C)(O[Na])=O
Biological Activity: IR-783 (ADS 780WS) is a heptamethine cyanine dye. IR-783 induces Mitochondrial membrane potential loss, ATP depletion, mitochondrial permeability transition pore opening, Cytochrome c release and Apoptosis in breast cancer cells. IR-783 promotes the translocation of Drp1 from the cytosol to mitochondria. IR-783 increases the expression of mitochondrial fission proteins such as MFF and Fission-1. IR-783 possesses imaging, cancer-targeting and anticancer properties. IR-783 exerts anticancer effects against breast cancer. IR-783 can be used in breast cancer-related research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IR-783 | 99.46% | IR-783 (ADS 780WS) is a heptamethine cyanine dye. IR-783 induces Mitochondrial membrane potential loss, ATP depletion, mitochondrial permeability transition pore opening, Cytochrome c release and Apoptosis in breast cancer cells. IR-783 promotes the translocation of Drp1 from the cytosol to mitochondria. IR-783 increases the expression of mitochondrial fission proteins such as MFF and Fission-1. IR-783 possesses imaging, cancer-targeting and anticancer properties. IR-783 exerts anticancer effects against breast cancer. IR-783 can be used in breast cancer-related research. | ||||||||||||||||||||
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