2 Results for "

murine choroidal neovascularization models

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "murine choroidal neovascularization models" in MCE Product Catalog:

Cat. No.: HY-113040B
Synonyms: (±)-17(S),18(R)-EETeTr
Target:  

Drug Isomer

Research Areas:  

Others

(±)-(17S,18R)-Epoxyeicosatetraenoic acid ((±)-17 (S),18 (R)-EETeTr) is one of the constituent enantiomers of (±) 17 (18)-EpETE. (±) 17 (18)-EpETE is an active metabolite of the ω-3 fatty acid eicosapentaenoic acid, and also an agonist of sphingosine-1-phosphate receptor 1 (S1P1) .
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Cat. No.: HY-P992151
Synonyms: LT1002
Sphingomab (LT1002) is a mouse-derived IgG1 κ monoclonal antibody and also an inhibitor targeting S1P, with high affinity for S1P and a Kd value of 0.03 ± 0.002 nM. Sphingomab blocks S1P-mediated IL-8 release in ovarian cancer cells. Sphingomab exhibits anti-angiogenic activity in a mouse model of choroidal neovascularization. Sphingomab reduces peripheral blood lymphocyte counts. Sphingomab can be used in the research of ovarian cancer and age-related macular degeneration .
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