Search Result

Results for "

phenylethanoid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldose Reductase (2) Angiotensin-converting Enzyme (ACE) (2) Apoptosis (4) Arrestin (2) Bacterial (2) Biochemical Assay Reagents (1) Calcium Channel (1) Caspase (2) CD38 (1) Drug Derivative (1) Endogenous Metabolite (2) Endothelin Receptor (1) Glycosidase (3) HIV (1) IKK (1) Interleukin Related (4) NF-κB (3) NO Synthase (1) NOD-like Receptor (NLR) (3) PKC (2) Reactive Oxygen Species (ROS) (4) Reference Standards (6) SARS-CoV (2) Sirtuin (1) SOD (2) TNF Receptor (2) Wnt (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (4) Infection (7) Inflammation/Immunology (18) Metabolic Disease (5) Neurological Disease (6)

By Targets:

Aldose Reductase (2)

Angiotensin-converting Enzyme (ACE) (2)

Apoptosis (4)

Arrestin (2)

Bacterial (2)

Biochemical Assay Reagents (1)

Calcium Channel (1)

Caspase (2)

CD38 (1)

Drug Derivative (1)

Endogenous Metabolite (2)

Endothelin Receptor (1)

Glycosidase (3)

HIV (1)

IKK (1)

Interleukin Related (4)

NF-κB (3)

NO Synthase (1)

NOD-like Receptor (NLR) (3)

PKC (2)

Reactive Oxygen Species (ROS) (4)

Reference Standards (6)

SARS-CoV (2)

Sirtuin (1)

SOD (2)

TNF Receptor (2)

Wnt (2)

By Research Areas:

Cancer (6)

Cardiovascular Disease (4)

Infection (7)

Inflammation/Immunology (18)

Metabolic Disease (5)

Neurological Disease (6)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0020

Echinacoside Maximum Cited Publications 20 Publications Verification	Wnt Reactive Oxygen Species (ROS)	Neurological Disease
Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .

HY-N0029

Forsythoside B 5+ Cited Publications	TNF Receptor NF-κB	Inflammation/Immunology
Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.

HY-N0028

Forsythiaside A 5 Publications Verification	Others	Inflammation/Immunology
Forsythiaside A is an orally active phenylethanoid glycoside isolated from the dried fruits of Forsythia suspensa. Forsythiaside A is also an inhibitor of COX-2 and has anti-inflammatory, antioxidant and neuroprotective effects. Forsythiaside A prevents neuroinflammation and apoptosis caused by Aβ_25-35 damage and may be used in Alzheimer's disease (AD) research. Forsythiaside A also activates the Nrf2/HO-1 signaling pathway and inhibits OVA-induced asthma in mice. Forsythiaside A inhibits the interaction between KLRB1 and CLEC2D .

HY-N2594

Isoforsythiaside	Bacterial	Infection
Isoforsythiaside is an antioxidant and antibacterial phenylethanoid glycoside with MICs of 40.83, 40.83, and 81.66 μg/mL for Escherichia coli(E. coli), Pseudomonas aeruginosa(PAO), and Staphylococcus aureus (SA), respectively .

HY-N2155

Tubuloside A 1 Publications Verification	Others	Metabolic Disease
Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-N5042

Forsythoside I	Interleukin Related NOD-like Receptor (NLR) Arrestin Caspase Apoptosis SOD	Inflammation/Immunology
Forsythoside I is an orally active caffeoyl phenylethanoid glycoside (CPG) that can be isolated from Forsythia suspense (Thunb.) Vahl. Forsythoside I has anti-inflammatory activity and can exert a protective effect in a mouse model of acute lung injury .

HY-N0539

Calceolarioside B	Aldose Reductase SARS-CoV Interleukin Related	Infection Inflammation/Immunology Cancer
Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC₅₀ value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer .

HY-N5063

Plantainoside D 2 Publications Verification	Angiotensin-converting Enzyme (ACE) IKK Calcium Channel PKC Reactive Oxygen Species (ROS) NF-κB Apoptosis Sirtuin NOD-like Receptor (NLR)	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Plantainoside D, a phenylethanoid glycosides, is a IKK-β inhibitor with diverse biological activities. Plantainoside D shows inhibitory activity of angiotensin-converting enzyme (ACE) with an IC₅₀ of 2.17 mM. Plantainoside D significantly reduces the release of glutamate from nerve terminals in the cerebral cortex of rats by inhibiting the voltage-dependent calcium channel (VDCCs) and protein kinase C (PKC) signaling cascade. Plantainoside D significantly alleviates cell apoptosis by inhibiting the generation of ROS and the activation of NF-κB. Plantainoside D significantly improves acute lung injury (ALI) induced by sepsis by regulating the Sirt3/NLRP3 signaling pathway. Plantainoside D can be used for the study of neuroprotection, antioxidant, anti-inflammation, antihypertension .

HY-N4220

Cistanoside F 2 Publications Verification	Others	Metabolic Disease
Cistanoside F is a phenylethanoid glycosid isolated from Cistanche deserticola, with antioxidative effect .

HY-N2173

Forsythoside E 1 Publications Verification	Others	Cardiovascular Disease Inflammation/Immunology
Forsythoside E is a phenylethanoid glycoside compound. Forsythoside E can be isolated from Shuanghuanglian. Forsythoside E does not induce vascular leakage or promote histamine release in mice. Forsythoside E does not cause pseudo-allergic reactions .

HY-N0023

Cistanoside A	NO Synthase	Inflammation/Immunology
Cistanoside A is a phenylethanoid isolated from Cistanche deserticola, reduces NO accumulation, but shows no effect on iNOS mRNA, iNOS protein levels or iNOS activity. Anti-inflammatory effect .

HY-N7637

Tubuloside B 3 Publications Verification	Apoptosis	Cancer
Tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, inhibits TNFα-induced apoptosis. Tubuloside B possesses antioxidative effects .

HY-N5043

Forsythoside H	Others	Inflammation/Immunology
Forsythoside H, a caffeoyl phenylethanoid glycoside (CPG) isolated from the fruits of Forsythia suspense (Thunb.) Vahl, may possesses anti-inflammatory activities .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-N6873

GL3	Others	Others
GL3, the major component of O. fragrans seeds, is a derivative based on both phenylethanoid and methyloleoside .

HY-N0020R

Echinacoside (Standard)	Reference Standards Wnt Reactive Oxygen Species (ROS)	Neurological Disease
Echinacoside (Standard) is the analytical standard of Echinacoside. This product is intended for research and analytical applications. Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-N3329

Magnoloside A	Others	Others
Magnoloside A (compound 4) is a main phenylethanoid glycoside in Houpo. Magnoloside A can be used in the research of functional dyspepsia (FD) .

HY-N16523

Ferruginoside C	Glycosidase	Cancer
Ferruginoside C is a phenylethanoid. Ferruginoside C can be isolated from V. leiocarpum. Ferruginoside C shows potent alpha-glucosidase inhibitory activity with an IC₅₀ of 19.93 μM. Ferruginoside C shows antioxidant activities. Ferruginoside C can be used in the research of cervical cancer, ovarian cancer, and colon cancer .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-123896

Calceolarioside A	HIV	Infection
Calceolarioside A is phenylethanoid glycoside with moderate binding affinity on HIV gp41 .

HY-N2090

Ligupurpuroside D	Others	Inflammation/Immunology
Ligupurpuroside D is a phenylethanoid glycoside that can be isolated from Ligustrum purpurascens. Ligupurpuroside D has antioxidant activity .

HY-N13188

2'-Rhamnoechinacoside Michelioside A	Glycosidase	Cancer
2'-Rhamnoechinacoside (Michelioside A), a compound of phenylethanoid glycosides, is a α-glucosidase inhibitor with anti-tumor activity, which is derived from Phlomis stewartii. 2'-Rhamnoechinacoside can be used for research of UV-absorbing and cancers .

HY-N2089

Ligupurpuroside C	Others	Inflammation/Immunology
Ligupurpuroside C is a natural phenylethanoid glycoside isolated from Kudingcha .

HY-N2155R

Tubuloside A (Standard)	Reference Standards Others	Metabolic Disease
Tubuloside A (Standard) is the analytical standard of Tubuloside A. This product is intended for research and analytical applications. Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-N8018

Leucosceptoside A	PKC Glycosidase Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease Neurological Disease Metabolic Disease
Leucosceptoside A is a phenylethanoid glycoside with anti-hyperglycemic and anti-hypertensive activities. Leucosceptoside A shows inhibitory activity against α-glucosidase and PKCα (IC₅₀ of 19.0 μM) .

HY-N12203

5-Deoxypulchelloside I	Others	Others
5-Deoxypulchelloside I is a magnoside glycoside that can be isolated from the aerial parts of the Lamiaceae plant Eremostachys laciniata .

HY-N0029R

Forsythoside B (Standard)	Reference Standards TNF Receptor NF-κB	Inflammation/Immunology
Forsythoside B (Standard) is the analytical standard of Forsythoside B. This product is intended for research and analytical applications. Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.

HY-N0028R

Forsythiaside A (Standard)	Reference Standards Others	Inflammation/Immunology
Forsythiaside A (Standard) is the analytical standard of Forsythiaside A. This product is intended for research and analytical applications. Forsythiaside A is an orally active phenylethanoid glycoside isolated from the dried fruits of Forsythia suspensa. Forsythiaside A is also an inhibitor of COX-2 and has anti-inflammatory, antioxidant and neuroprotective effects. Forsythiaside A prevents neuroinflammation and apoptosis caused by Aβ25-35 damage and may be used in Alzheimer's disease (AD) research. Forsythiaside A also activates the Nrf2/HO-1 signaling pathway and inhibits OVA-induced asthma in mice .

HY-N0539R

Calceolarioside B (Standard)	Aldose Reductase Reference Standards SARS-CoV Interleukin Related	Infection Inflammation/Immunology Cancer
Calceolarioside B (Standard) is the analytical standard of Calceolarioside B (HY-N0539). This product is intended for research and analytical applications. Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC₅₀ value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer .

HY-N0109A

(S)-Salidroside	Drug Derivative	Others
(S)-Salidroside is a tyrosine-derived phenylethanoid glycoside natural product .

HY-N17897

Tubuloside E	Endogenous Metabolite	Others
Tubuloside E is a phenylethanoid glycoside compound that can be isolated from the whole plant of Cistanche tubulosa (Schrenk) Hook. f. (Orobanchaceae) .

HY-N1871

4-(2-Hydroxy-1-methoxyethyl)-1,2-benzenediol	Others	Inflammation/Immunology
4-(2-Hydroxy-1-methoxyethyl)-1,2-benzenediol is a phenylethanoid isolated from the stem bark of Syringa reticulate (Bl.) Hara (Oleaceae) with expectorant and antiasthmatic activity .

HY-N2091

cis-Ligupurpuroside B	Others	Others
cis-Ligupurpuroside B is a phenylethanoid glycoside that can be found L. purpurascens .

HY-N17342

cis-Verbascoside cis-Acteoside; cis-Kusaginin; cis-TJC160	Others	Others
cis-Verbascoside (cis-Acteoside) is a phenylethanoid that can be found in Blepharis edulis .

HY-N17780

Picfeoside A	Endogenous Metabolite	Infection Metabolic Disease Inflammation/Immunology
Picfeoside A is a phenylethanoid glycoside compound that can be isolated from Picria felterrae Lour. Picfeoside A can be used in research related to diseases such as fever, herpes infections, cancer, and inflammation.

HY-N17823

Plantagoside A	Others	Inflammation/Immunology
Plantagoside A (Compound 3) is a phenylethanoid glycoside found in Plantago asiatica. Plantagoside A has antioxidant activity and can inhibit lipid peroxidation in rat liver microsomes induced by ADP and NADPH with an IC₅₀ of 0.54 μM .

HY-N17784

Peiioside A	Others	Infection Neurological Disease
Peiioside A is a phenylethanoid glycoside compound that can be isolated from the leaves and stems of Callicarpa longissima. Callicarpa longissima has traditional medicinal uses for treating colds, coughs, arthritis, and bleeding, and can be used in the research of anti-inflammatory and antibacterial agents, as well as in neuroprotection-related fields.

HY-N17767

Leonoside F	Others	Inflammation/Immunology
Leonoside F is a phenylethanoid glycoside compound isolated from the aerial parts of Leonurus japonicus Houtt., which protects liver cells from chemically induced damage. At a concentration of 1×10 ^-5 M, Leonoside F shows significant hepatoprotective activity against D-galactosamine-induced damage in HL-7702 liver cells, with an inhibition rate of 30.9% .

HY-N12696

Cistanoside H	Reactive Oxygen Species (ROS)	Neurological Disease
Cistanoside H is a phenylethanoid glycoside neuroprotective agent that can be isolated from the leaves and twigs of Callicarpa dichotoma. Cistanoside H can alleviate glutamate-induced oxidative stress and protect rat cortical cells from neurotoxic damage. Cistanoside H protects nerve cells against excitotoxic damage and can be applied in research related to neurodegenerative diseases (such as Alzheimer's disease and Parkinson's disease).

HY-N5042R

Forsythoside I (Standard)	Reference Standards Interleukin Related NOD-like Receptor (NLR) Arrestin Caspase Apoptosis SOD	Inflammation/Immunology
Forsythoside I (Standard) is the analytical standard of Forsythoside I (HY-N5042). This product is intended for research and analytical applications. Forsythoside I is an orally active caffeoyl phenylethanoid glycoside (CPG) that can be isolated from Forsythia suspense (Thunb.) Vahl. Forsythoside I has anti-inflammatory activity and can exert a protective effect in a mouse model of acute lung injury .

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

Cat. No.	Product Name	Target	Research Area