105471-98-5
Chemical Structure
Calceolarioside B
- CAS No.: 105471-98-5
- Formula:C23H26O11
- Molecular Weight:478.45
IUPAC Name: ((2R,3S,4S,5R,6R)-6-(3,4-dihydroxyphenethoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl (E)-3-(3,4-dihydroxyphenyl)acrylate
InChIKey: LFKQVVDFNHDYNK-FOXCETOMSA-N
SMILES: O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1COC(/C=C/C2=CC(O)=C(O)C=C2)=O)OCCC3=CC(O)=C(O)C=C3
Biological Activity: Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC50 value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer[1][2][3][4].
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Calceolarioside B | 99.72% | Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC50 value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer. | ||||||||||||||||||||
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Calceolarioside B (Standard) | ≥98% | Calceolarioside B (Standard) is the analytical standard of Calceolarioside B (HY-N0539). This product is intended for research and analytical applications. Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC50 value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer. | ||||||||||||||||||||
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- [1]. Hwang SH, et al. Inhibitory Activities of Stauntonia hexaphylla Leaf Constituents on Rat Lens Aldose Reductase and Formation of Advanced Glycation End Products and Antioxidant. Biomed Res Int. 2017;2017:4273257. [Content Brief]
- [2]. Zheng X, et al. Identification of the functional food ingredients with antithrombotic properties via virtual screen and experimental studies. Food Chem. 2021 Nov 15;362:130237. [Content Brief]
- [3]. Mulani SK, et al. A general synthetic strategy and the anti-proliferation properties on prostate cancer cell lines for natural phenylethanoid glycosides. Org Biomol Chem. 2014 May 14;12(18):2926-37. [Content Brief]
- [4]. Lin XB, et al. Calceolarioside B inhibits SARS-CoV-2 Omicron BA.2 variant cell entry and modulates immune response. Virol J. 2024 Dec 21;21(1):329. [Content Brief]
