2. Apoptosis
  3. Apoptosis
  4. Tubuloside B

Tubuloside B 

Cat. No.: HY-N7637 Purity: 98.57%
COA Handling Instructions

Tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, inhibits TNFα-induced apoptosis. Tubuloside B possesses antioxidative effects.

For research use only. We do not sell to patients.

Tubuloside B Chemical Structure

Tubuloside B Chemical Structure

CAS No. : 112516-04-8

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, inhibits TNFα-induced apoptosis. Tubuloside B possesses antioxidative effects[1][2].

In Vitro

Pretreatment with tubuloside B (1, 10, or 100 mg/L) for 2 h attenuates the TNFα-mediated apoptosis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

666.62

Appearance

Solid

Formula

C31H38O16
CAS No.
SMILES
Structure Classification
Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (15.00 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5001 mL 7.5005 mL 15.0010 mL
5 mM 0.3000 mL 1.5001 mL 3.0002 mL
10 mM 0.1500 mL 0.7501 mL 1.5001 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 1 mg/mL (1.50 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1 mg/mL (1.50 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 1 mg/mL (1.50 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Keywords:

Tubuloside B112516-04-8ApoptosisInhibitorinhibitorinhibit

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