2 Results for "

platinum-based chemotherapy

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "platinum-based chemotherapy" in MCE Product Catalog:

Cat. No.: HY-P991628
Synonyms: PF-08634404

Target:  

PD-1/PD-L1 VEGFR

Research Areas:  

Cancer

SSGJ-707 (PF-08634404) is a bispecific antibody targeting VEGF and PD-1. SSGJ-707 exerts dual anti-tumor effects by neutralizing VEGF and blocking the PD-1 signaling pathway. SSGJ-707 can be combined with platinum-based chemotherapy to inhibit advanced non-small cell lung cancer (NSCLC), and its inhibitory effect is not limited by PD-L1 expression levels. In the HARMONi-2 trial, the objective response rate of SSGJ-707 correlates with the PD-L1 tumor proportion score, and the incidence of grade ≥3 adverse events is comparable to that of Inetetamab (HY-P99969). SSGJ-707 is being extensively investigated for a variety of malignancies including advanced NSCLC, colorectal cancer and small cell lung cancer .
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Cat. No.: HY-161623
CAS No.: 3078058-57-5
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

ERCC1/XPA interaction inhibitor 1 (compound 27o) is a potent ERCC1/XPA67-80 interaction inhibitor with an EC50 value of 4.7 µM. ERCC1/XPA interaction inhibitor 1 has the potential for the research of DNA damaging agents and overcoming resistance to platinum-based chemotherapy .
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